Comparing Methylphenidate vs Xywav
| Methylphenidate | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) |
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| Methylphenidate | Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) |
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Prescription only
Methylphenidate can help improve symptoms of ADHD but may cause dependence and side effects include a headache, loss of appetite, and sleeplessness. It is recommended that methylphenidate should not... View more |
Prescription only
Xywav may be used to treat idiopathic hypersomnia in adults or narcolepsy in adults and children aged 7 and older. It contains 92% less sodium than sodium oxybate (Xyrem) because it is made up of a... View more |
Related suggestions |
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| More about Methylphenidate | More about Xywav (calcium oxybate / magnesium oxybate / potassium oxybate / sodium oxybate) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Methylphenidate has an average rating of 7.2 out of 10 from a total of 1082 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 17% reported a negative effect. |
Xywav has an average rating of 8.1 out of 10 from a total of 16 ratings on Drugs.com. 81% of reviewers reported a positive effect, while 13% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Methylphenidate side effects |
View all Xywav side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Methylphenidate prices |
View all Xywav prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Aptensio XR, Concerta, Cotempla XR-ODT, Daytrana, Jornay PM, Metadate CD, Methylin, Methylin ER, QuilliChew ER, Quillivant XR, Relexxii, Ritalin, Ritalin LA View more |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4 hours |
0.66 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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High potential for abuse
Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. |
Moderate abuse potential
Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 207 drugs are known to interact with Methylphenidate:
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A total of 346 drugs are known to interact with Xywav:
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 05, 1955 |
July 21, 2020 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.