Comparing Methotrexate vs Opdivo
Methotrexate | Opdivo |
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Methotrexate | Opdivo (nivolumab) |
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Prescription only
Methotrexate may be considered for the treatment of psoriasis or rheumatoid arthritis if other treatments have failed. It may also be used in certain cancers. Side effects can be severe and... View more |
Prescription only
Opdivo is an immune checkpoint inhibitor that may be used to treat many different cancers including melanoma, bladder cancer, liver cancer, and lung cancer. Fatigue, skin conditions, a cough, upper... View more |
Related suggestions Colorectal Cancer
Esophageal Carcinoma
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More about Methotrexate | More about Opdivo (nivolumab) | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Methotrexate has an average rating of 6.6 out of 10 from a total of 334 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 23% reported a negative effect. |
Opdivo has an average rating of 5.3 out of 10 from a total of 87 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 47% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: methotrexate side effects in more detail. |
See also: Opdivo side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
N/A |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all methotrexate prices |
View all Opdivo prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Jylamvo, Methotrexate LPF Sodium, Otrexup, Rasuvo, Trexall, Xatmep |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
15 hours |
640.8 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 694 drugs are known to interact with methotrexate:
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A total of 16 drugs are known to interact with Opdivo:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
December 07, 1953 |
December 22, 2014 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.