Comparing Losartan vs Sacubitril / Valsartan
| Losartan | Sacubitril / valsartan |
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| Losartan | Sacubitril / valsartan |
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Prescription only
Losartan works on a hormone called angiotensin II to lower blood pressure and may also improve kidney function in some people. People being initiated on losartan should be adequately rehydrated and... View more |
Prescription only
Prescribed for Heart Failure. Sacubitril / valsartan may also be used for purposes not listed in this medication guide. |
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| More about Losartan | More about Sacubitril / valsartan | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Losartan has an average rating of 4.5 out of 10 from a total of 578 ratings on Drugs.com. 26% of reviewers reported a positive effect, while 48% reported a negative effect. |
Sacubitril / valsartan has an average rating of 5.0 out of 10 from a total of 203 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 47% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Losartan side effects |
View all Sacubitril / valsartan side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Losartan prices |
View all Sacubitril / valsartan prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Arbli, Cozaar | Entresto, Entresto Sprinkle | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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4.4 hours |
11.5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 326 drugs are known to interact with Losartan:
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A total of 335 drugs are known to interact with Sacubitril / valsartan:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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April 14, 1995 |
July 07, 2015 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.