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Losartan Dosage

Medically reviewed by Drugs.com. Last updated on Jun 29, 2023.

Applies to the following strengths: 25 mg; 50 mg; 100 mg

Usual Adult Dose for Diabetic Nephropathy

Initial dose: 50 mg orally once a day
Maximum dose: 100 mg orally once a day

Comments:


Uses:

Usual Adult Dose for Hypertension

Initial dose: 50 mg orally once a day
Maximum dose: 100 mg orally once a day

Comments:


Uses:

Usual Pediatric Dose for Hypertension

6 Years or Older:
Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total)

Comments:

Renal Dose Adjustments

Adult:
No adjustment recommended

Pediatric:
GFR less than 30 mL/min/1.73 m2: Not recommended

If a clinically significant decrease in renal function develops during therapy: Consider withholding or discontinuing this drug.

Liver Dose Adjustments

Mild to moderate liver dysfunction: Initial dose: 25 mg orally once a day
Severe liver dysfunction: Data not available

Dose Adjustments

Patients with possible intravascular volume depletion:

Precautions

US BOXED WARNING:


Safety and efficacy have not been established in patients younger than 6 years.

Consult WARNINGS section for additional precautions.

Dialysis

No adjustment recommended

Other Comments

Administration advice: Pediatric dose may be administered as a tablet or suspension.

Storage requirements: Prepared suspension should be refrigerated at 2 to 8C (36 to 46F) and can be stored for up to 4 weeks.

Reconstitution/preparation techniques: The manufacturer product information should be consulted.

Monitoring:


Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.