Comparing Levothyroxine vs Propylthiouracil
| Levothyroxine | Propylthiouracil |
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| Levothyroxine | Propylthiouracil |
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Prescription only
Levothyroxine replaces missing thyroxine and is the preferred medicine to treat hypothyroidism. The dosage of levothyroxine needs to be tailored for each individual and there is a fine line between... View more |
Prescription only
Prescribed for Thyroid Storm, Hyperthyroidism, Alcoholic Liver Damage. Propylthiouracil may also be used for purposes not listed in this medication guide. |
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| More about Levothyroxine | More about Propylthiouracil | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Levothyroxine has an average rating of 5.2 out of 10 from a total of 873 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 46% reported a negative effect. |
Propylthiouracil has an average rating of 4.8 out of 10 from a total of 4 ratings on Drugs.com. 25% of reviewers reported a positive effect, while 50% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Levothyroxine side effects |
View all Propylthiouracil side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Levothyroxine prices |
View all Propylthiouracil prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Eltroxin, Ermeza, Euthyrox, Eutroxsig, Evotrox, Levo-T, Levolet, Levoxyl, Novothyrox, Synthroid, Thyquidity, Tirosint, Tirosint-Sol, Unithroid View more |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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240 hours |
5 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category A
Studies show no risk
See the full pregnancy warnings document. |
Category D
Positive evidence of risk
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 239 drugs are known to interact with Levothyroxine:
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A total of 66 drugs are known to interact with Propylthiouracil:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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August 21, 2000 |
July 28, 1947 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.