Skip to main content
Print

Levemir Alternatives Compared

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Levemir Semaglutide Metformin
View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Levemir (insulin detemir) Semaglutide Metformin
Prescription only

Levemir contains insulin detemir in a FlexTouch prefilled pen or 10mL vial. Levemir is long-acting and may be used to treat adults and children over the age of two years with diabetes. Levemir may... View more

Prescription only

Semaglutide lowers blood sugar levels by mimicking the effects of GLP-1, a naturally occurring hormone that stimulates insulin secretion and lowers glucagon secretion from the liver. It is taken... View more

Prescription only

Metformin improves how the body responds to insulin and it is effective for the treatment of type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side... View more

More about Levemir (insulin detemir) More about Semaglutide More about Metformin
Generic Status

No lower-cost generic available

No lower-cost generic available

Lower-cost generic is available
Ratings & Reviews

Levemir has an average rating of 4.7 out of 10 from a total of 67 ratings on Drugs.com. 31% of reviewers reported a positive effect, while 53% reported a negative effect.

Semaglutide has an average rating of 6.3 out of 10 from a total of 1726 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 29% reported a negative effect.

Metformin has an average rating of 6.8 out of 10 from a total of 643 ratings on Drugs.com. 55% of reviewers reported a positive effect, while 19% reported a negative effect.

View all 67 reviews

View all 1726 reviews

View all 643 reviews

Drug Class
Side Effects

Common side effects include:

  • severe hypoglycemia

See also: Levemir side effects in more detail.

See also: semaglutide side effects in more detail.

Commonly reported side effects include:

  • lactic acidosis
  • diarrhea
  • nausea
  • nausea and vomiting
  • vomiting
  • flatulence

See also: metformin side effects in more detail.
Pricing and Coupons * Prices are without insurance
Quantity 15 mL
Dosage 100 units/mL
Per Unit* $33.08
Cost* $496.21

View all Levemir prices

We could not find an exact match for this medicine. Try searching the Price Guide directly.
Quantity 100 each
Dosage 500 mg
Per Unit* $0.16 - $0.22
Cost* $16.02 - $22.18

View all metformin prices

Get free Discount Card

Get free Discount Card

Get free Discount Card

Dosage Form(s) Available
  • Subcutaneous solution

N/A
  • Oral solution
  • Oral tablet
  • Oral tablet, extended release
Brand Names

N/A

 Ozempic, Rybelsus, Wegovy Glumetza
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

7 hours

168 hours

4.5 hours
CSA Schedule ** View glossary of terms
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
Pregnancy Category
B
Category B No proven risk in humans

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.
B
Category B No proven risk in humans

See the full pregnancy warnings document.
Drug Interactions

A total of 382 drugs are known to interact with Levemir:

  • 15 major drug interactions (39 brand and generic names)
  • 346 moderate drug interactions (1835 brand and generic names)
  • 21 minor drug interactions (210 brand and generic names)

A total of 248 drugs are known to interact with semaglutide:

  • 2 major drug interactions (5 brand and generic names)
  • 245 moderate drug interactions (1404 brand and generic names)
  • 1 minor drug interactions (10 brand and generic names)

A total of 361 drugs are known to interact with metformin:

  • 20 major drug interactions (113 brand and generic names)
  • 332 moderate drug interactions (1748 brand and generic names)
  • 9 minor drug interactions (35 brand and generic names)
Alcohol/Food/Lifestyle Interactions
  • Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood... View more
  • Semaglutide may affect the absorption of other medications that you take by mouth. In some cases... View more
  • Talk to your doctor before using alcohol together with semaglutide. Alcohol may affect blood... View more
  • MetFORMIN should be taken with meals, and excessive alcohol intake (either short-term binge... View more
Disease Interactions
First Approval Date

June 16, 2005

December 05, 2017

March 03, 1995
WADA Class View World Anti-Doping Agency classifications.

N/A

N/A

N/A
More Information
Patient resources
Professional Resources
Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Compare Drugs

To view a report comparing 3 (or more) medications, please sign in or create an account.

Create an account Sign In