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Comparing Imodium vs Lomotil

Imodium

loperamide

Lomotil

atropine / diphenoxylate

Prescribed for Traveler's Diarrhea, Diarrhea - Chronic, Diarrhea - Acute, Diarrhea. Imodium may also be used for purposes not listed in this medication guide.

Prescribed for Diarrhea. Lomotil may also be used for purposes not listed in this medication guide.

Prescription and OTC

Prescription only

Ratings & Reviews

Recent helpful reviews
7.8
15 Reviews

For Diarrhea Works.

9
Natkoll

For Diarrhea I get diarrhea all the time since I was 12 or 13. I take a lot of meds, and a lot of food I can no longer eat. This medicine works right away for me. I am now 67 yrs old. I only use it if the diarrhea lasts for more than two days.

10
pees
7.8
29 Reviews

For Diarrhea I have been taking Lomotil since I had surgery to repair a fistula in my intestines. I have crohn's and am 38yr old male. The Lomotil has made it somewhat bearable and I have not had as many bouts of liquid feces since taking. Not a miracle drug but does help in a tremendous way. I suggest that you try it if you have disease that I have. Cannot stress NOT MIRACLE DRUG, BUT DOES HELP TREMENDOUSLY.

8
Anon38from1978

For Diarrhea I have recently been diagnosed with C diff, which is a very bad bowel infection. I have lost 20 pounds due to severe diarrhea from the C diff. My doctor prescribed me the lomotil 3 times a day to help with the urgent bouts of diarrhea. I find taking 1-2 seems to be effective enough to not have the watery poops but enough I can live my life without urgency to go to the washroom. I've been stuck at home for over a month with worry about not finding a bathroom in time. This medicine has helped me enough to be able to enjoy some things without severe pain and diarrhea.

8
Britt306123

View all 15 reviews

View all 29 reviews

Drug Class

Side Effects

See the full Imodium side effects document.

See the full Lomotil side effects document.

Pricing and Coupons

* Prices are without insurance

We could not find an exact match for this medicine. Try searching the Price Guide directly.
Quantity 12 tablet
Dosage 0.025 mg-2.5 mg
Per Unit* $2.11
Cost* $25.37
View all Lomotil prices
View generic prices

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Generic Availability

Yes

Yes

Dosage Form(s) Available
N/A
  • Oral tablet

Brand Names
Other loperamide brands include: A-D Anti-Diarrheal, Anti-Diarrheal, Diamode, Diar-Aid, Imodium A-D, Imotil, Kao-Paverin, Kaopectate... more Other atropine / diphenoxylate brands include: Logen, Lomanate, Lomocot, Lonox, and Vi-Atro

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

10.8 hours

14 hours

CSA Schedule**

View glossary of terms.
N
Not a controlled drug

Is not subject to the Controlled Substances Act.
5
Some potential for abuse

Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.

Pregnancy Category
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.
C
Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (2)

FDA Alerts (1)

Drug Interactions

A total of 626 drugs are known to interact with Imodium:

  • 57 major drug interactions (208 brand and generic names)
  • 568 moderate drug interactions (3585 brand and generic names)
  • 1 minor drug interactions (7 brand and generic names)

A total of 745 drugs are known to interact with Lomotil:

  • 21 major drug interactions (135 brand and generic names)
  • 646 moderate drug interactions (4700 brand and generic names)
  • 78 minor drug interactions (695 brand and generic names)

Alcohol/Food/Lifestyle Interactions
  • Alcohol can increase the nervous system side effects of loperamide such as dizziness, drowsiness,... more
  • Alcohol can increase the nervous system side effects of diphenoxylate such as dizziness,... more

Disease Interactions

First Approval Date

December 28, 1976

September 15, 1960

WADA Class

View World Anti-Doping Agency classifications.

N/A

N/A

More Information

Consumer Resources

Professional Resources

Related Treatment Guide

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Disclaimer: This site is designed to offer information for general educational purposes only. The health information furnished on this site and the interactive responses are not intended to be professional advice and are not intended to replace personal consultation with a qualified physician, pharmacist, or other healthcare professional. You must always seek the advice of a professional for questions related to a disease, disease symptoms, and appropriate therapeutic treatments.

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