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Imodium (loperamide) Drug Interactions

A total of 649 drugs are known to interact with Imodium (loperamide).

  • 58 major drug interactions
  • 590 moderate drug interactions
  • 1 minor drug interaction

Show all medications in the database that may interact with Imodium (loperamide).

Check for interactions with Imodium (loperamide)

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Common medications checked in combination with Imodium (loperamide)

  • acetaminophen (Tylenol, Paracetamol, Panadol, Mapap, Tylenol Extra Strength, Tylenol Arthritis Pain, Ofirmev, Perfalgan, Arthritis Pain Relief, Children's Tylenol, Tempra, Dafalgan, Doliprane, Paracetamol Almus, Panadol Osteo, Cipla Genpharm Paracetamol, Infant's Tylenol, Efferalgan, Cetafen, Altenol, Lemsip Original, Panadol Soluble, Feverall, Pharbetol, Liquiprin, Paracetamol Teva, Aminofen, Miradol, Panadol ActiFast, Mapap Arthritis Pain, Priceline Paracetamol, Tylophen, Genapap, Pain Clear Paracetamol, Tylenol 8 Hour, Capital Chemist Paracetamol, Pharmacy Health Own Name Paracetamol for Children, Chemists Own Paracetamol Pain & Fever 1 Month to 2 Years, Aceta, Buckley's Complete, Panamol, Taminol, Anacin Aspirin Free, Paracetamol Biogaran, Actamin, Paracetamol Ranbaxy, Paracetamol Sandoz, Q-Pap, Atasol, Perfalgan Nourrissons Et Enfants, Acetaminophen-odan, Remedol, Panamax, Paralgin, Febridol, Lemsip Childrens Cold & Flu, Orajel Maximum Strength Toothache, Paraspen, RP Scherer Paracetamol, Promax, Terry White Chemists Paracetamol, Pharmacist Advice Paracetamol, Terry White Chemists Paracetamol Colourfree Children 5-12 Years, Paracare, Tylenol Childrens Paracetamol, Conney Aspirin-Free, Panadol Gel Caps, Pacimol Caplets, Pharmore Paracetamol, Basics Paracetamol, Sigma Pain Relief, Setamol, Paraspen Drops, Panadol Colourfree Drops, Pharmacist Paracetamol Infant Drops, Pharmacist Paracetamol Infant Drops Colour Free, Bi-Lo Paracetamol, Pain-Eze Paracetamol Infant Drops Colour Free, Pharmaction Paracetamol, Biochemie Paracetamol, Healthsense Pain Relief Drops Children 1 Month to 2 Years, Black And Gold Paraceatmol, Pharmacist Advice Paracetamol Infant Drops, Black and Gold Paracetamol, Hexal Comfarol, Blooms the Chemist Paracetamol, Panadol Extend, Abenol, Paracetamol Soluble, Vitapap, Bristol Pharma Paracetamol, Sigma Paracetamol, Actimol Infant, ConRx Extra Strength, PediaCare Infants' Acetaminophen Fever Reducer/Pain Reliever, PediaCare Children's Acetaminophen Fever Reducer/Pain Reliever, Pharmacy Health Paracetamol Colour Free Childrens, PediaCare Smooth Melts Acetaminophen Fever Reducer/Pain Reliever, Pharmacy Health Paracetamol Colour Free Infants and Childrens Drops 1 Month-4 Years, Mapap Children's, Lemsip Cold and Flu Liquid Capsule, Children's Silapap, Febrol Solution, Febridol Infant Drops, Accidental Rapatabs, Chem Mart Chemadol Children 1 to 5 Years, Chem Mart Chemadol Colourfree, Chem Mart Chemadol Colourfree Children 5-12 Years, Chemists Own Chiildrens Paracetamol 5-12 Years, Lemsip Headcold, Chemists Own Childrens Paracetamol 1-5 Years, Lemsip Max, Chemists Own Paracetamol, Chemists Own Paracetamol Capseals, Chemists Own Paracetamol Pain & Fever 1 to 5 Years, Chemists Own Paracetamol Pain and Fever 5 to 12 Years, A-Pak Laboratories Paediatric Analgesic Paracetamol, Chemplus Paracetamol, Chemworld Colourfree Childrens Paracetamol Double Strength 5-12 Years, Chemworld Colourfree Childrens Paracetamol Junior 1-5 Years, Chemworld Paracetamol, Chemworld Paracetamol Infant Colour Free, HyVee Health 8 Hour Pain Relief, Bydol, Chem Mart Chemadol, Leader 8 Hour Pain Reliever, Children's ElixSure, Little Fevers, Mapap Rapid Release Gelcaps, Benylin Sore Throat, Fawns & McAllan Paracetamol, Zee Unaspirin ES, Chem Mart Chemadol Colourfree Childrens 1-5 Years, Midol Long Lasting Relief, Childrens Panadol 1 - 5 Years Colourfree, Childrens Panadol 1 - 5 Years, Childrens Panadol 5 - 12 Years Colourfree, Childrens Panadol 5 - 12 Years, Equaline Pain Relief, Help I Have A Headache, Febridol Clear Effervescent, Herron Paracetamol Tabsules, Panadol Rapid Handipak, Paralgin Paracetamol Tabsules, Pharmacist Childrens Paracetamol Colourfree 1-5 Years, Pharmacist Childrens Paracetamol Colourfree 5-12 Years, Pharmacy Health Colour Free Childrens Paracetamol, Gold Cross Paracetamol, Tylenol Cold Sore Throat, Alpha First Aid Supplies Paracetamol, Guardian Childrens Paracetamol 5-12 Years, Guardian Paracetamol, Guardian Paracetamol Tabsules, Acephen, Rex Paracetamol, Topcare Arthritis Pain Relief, Accidental First Aid Supplies Paracetamol, Panadol Childrens, Panadol Jr, Flu Strength Hot Lemon Powders, Paineze Paracetamol, Health Care Chemist Paracetamol Infant Drops Colour Free, Genebs, Herron Gold Paracetamol Tabsules, Tylenol Regular Strength, Herron Paracetamol, Tempra 2, Tempol, Herron Paracetamol Capseals, Tempra 3, Herron Paracetamol Capseals Handy Pack, Herron Paracetamol Handy Pack, Apra, Q-Nol, Claradol, Conacetol, Dolono, Doliprane Adultes, Coles Paracetamol, Genapap Extra Strength, Doliprane Sans Sucre, Dolitabs, Home Brand Paracetamol, Q-Pap Extra Strength, Dolko, ICN Paracetamol, Redutemp, Dolko Enfants, Dolotec, Vicks Formula 44 Custom Care Body Aches, James Dean Pharmacy Paracetamol, Pain-Eze, Efferalgan Pediatrique, Uniserts, Efferalganodis, Silapap Childrens, Expandox, Dolono Infant, Geluprane, Paracetamol Arrow, Ed-APAP, Paracetamol EG, St. Joseph Aspirin-Free, Country Chemists Paracetamol, Paracetamol Ivax, Paracetamol Merck, Paracetamol Qualimed, Adprin B, BF-Paradac, Paracetamol RPG, DG Health Pain Reliever, Tempra Quicklets, Paracetamol Sandoz Conseil, Tycolene, Lloydspharmacy Paracetamol Six Plus, Paracetamol Winthrop, Triaminic Fever Reducer Pain Reliever, Lloydspharmacy Paracetamol Infant, Paracetamol Zydus, Triaminic Infant Drops, Atasol Forte, Paralyoc, Tylenol Cool Caplet Extra Strength, Mapap Rapid Tabs, Jr. Tylenol, Mapap Extra Strength Rapid Burst, Elixsure Fever/Pain, Infadrops, Tactinal, Disprol Soluble Paracetamol, Calpol Infant, Disprol Paracetamol, Galpamol, Paldesic, Calpol Paediatric, Medinol Paediatric, Medinol Under 6, Alvedon, Infantaire Drops, Lemsip Pharmacy Non-Decongestant Formula, Calpol Fastmelts, Calpol Six Plus, Masophen, Medinol Over 6, Nortemp Children's, Paracets, Anadin Paracetamol, Hedex, UN-Aspirin Extra Strength, Mandanol, Valorin, Actimol Children's, Dakota Paracetamol, Umphamol, Panamax 240, Parahexal, Mid West Products Numol Paracetamol, Parmol, Silapap Infants, Cuprofen for Children, Mapap Infant Drops, Mandanol Infant, Cetafen Extra, Mandanol 6+, Fennings Childrens Cooling, Duatrol SR, Aldi Hedanol Paracetamol, Under Ten Care Infant, Alphapharm Paracetamol, Amadol Paracetamol, No Frills Paracetamol, Tylenol Sore Throat Daytime, Nova Paracetamol, Mapap Meltaway, Numark Paracetamol, Amcal Childrens Paracetamol 1-5 Years, Nyal Paracetamol, Medi-Tabs, Amcal Childrens Paracetamol 5-12 Years, Amcal Paracetamol Pain Relief, Ordov Febrigesic Paracetamol, Topcare 8 Hour Pain Relief, Amcal Paracetamol Infant Drops 1 Month to 2 Years, Pain-Eze Paracetamol Infant Drops, Febridol Syrup for Children, Amcal Paracetamol Tabsules, Pharmacist Advice Colourfree Childrens Paracetamol Double Strength, Guardian Childrens Paracetamol, Pharmacist Formula Paracetamol, Pharmacist Formula Infants, RP Scherer Paracetamol Liquid-Filled Capsules, Savings Paracetamol, Signature Range Paracetamol, Dymadon, Soul Pattinson Childrens Paracetamol Elixir, Soul Pattinson Colour Free Paracetamol 1-5 Years, Soul Pattinson Colour Free Paracetamol Drops, Soul Pattinson Colourfree Childrens Paracetamol, Panadol Gel Tabs, API Healthcare Coloufree Childrens Paracetamol, Soul Pattinson Paracetamol, API Healthcare Colourfree Childrens Paracetamol Double Strength, Soul Pattinson Paracetamol Clear Effervescent, Panadol Mini Caps, API Healthcare Paracetamol, Pharmacy Health Paracetamol, Terry White Chemists Colour Free Paracetamol 1-5 Years, Pharmacist Paracetamol, Terry White Chemists Colour Free Paracetamol Infant Drops)
  • Advil (ibuprofen)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Ecotrin Adult Low Strength, Bufferin, Aspiritab, Arthritis Pain, Fasprin, Halfprin, Easprin, Durlaza, Aspirtab, St. Joseph 81 mg Chewable Aspirin, Aspergum, Low Dose ASA, Buffered Aspirin, Ecotrin Maximum Strength, Ascriptin Enteric, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Aspirin Lite Coat, Bayer Aspirin Regimen, Aspi-Cor, Empirin, Bayer Children's Aspirin, Bufferin Extra Strength, St. Joseph Aspirin, Bayer Women's Aspirin With Calcium, Miniprin, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Entercote, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Zero-Order Release, YSP Aspirin, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Augmentin (amoxicillin / clavulanate)
  • azithromycin (Zithromax, Azithromycin Dose Pack, Z-Pak, Zmax)
  • Benadryl (diphenhydramine)
  • Cipro (ciprofloxacin)
  • dicyclomine (Bentyl, Dicyclocot, Bentyl Syrup, Byclomine, Bemote, Di-Spaz, Dibent, Dilomine)
  • doxycycline (Vibramycin, Doxy 100, Oracea, Monodox, Adoxa, Doryx, Acticlate, Vibra-Tabs, Targadox, Doxy 200, Doxy-D, Oraxyl, Alodox, Morgidox, Adoxa Pak, Avidoxy, Uracil, Periostat, Doryx MPC, Doxy-Caps, Adoxa TT, Adoxa CK, Ocudox, LymePak, Mondoxyne NL, NicAzel Doxy, Doxy-Lemmon)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • Lasix (furosemide)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Unithroid, Levothyrox, Euthyrox, Levo-T, L Thyroxine Roche, Eutroxsig, Novothyrox, Oroxine, Tirosint-Sol, Levotabs, Levotec, Evotrox)
  • Lexapro (escitalopram)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • Lomotil (atropine / diphenoxylate)
  • metformin (Glucophage, Glucophage XR, Glumetza, Riomet, Fortamet)
  • metoprolol (Metoprolol Tartrate, Metoprolol Succinate ER, Toprol-XL, Lopressor, Kapspargo Sprinkle)
  • multivitamin (Metanx, Daflon, Theragran, Folbic, Estroven, Nephro-Vite, Neurobion, Rena-Vite, Vitamins, Cerefolin, Foltx, Folbee, Nephrocaps, Foltanx, Cod Liver Oil, Multi Vitamin+, Cerefolin NAC, Thera, Vitamin B Complex 100, B Complex 100, PoDiaPN, Super B Complex, Lipoflavonoid, Cod Liver Oil Mint, Folic Acid XTRA, Rheumate, Daily Multiple Vitamins, Daily Vite, Nephplex Rx, Infuvite, One-A-Day 50+, Renal Caps, Tab-A-Vite, Essentiale, MVI Adult, Foltrate, Xyzbac, Berocca, Reno Caps, Chewable-Vite, Flintstones Multivitamins, Triphrocaps, Fletanol, Folinic-Plus, Nephro-Vite Rx, Poly-Vi-Sol, Lysiplex, Super B-50, B Complex 50, Nephronex, FaBB, Mebolic, TL Gard, StressTabs, B-Stress, Surbex with C, Surbex, Scotts Emulsion, Hylavite, Prostate 2.4, Rena-Vite Rx, Topfit Vitamin B Complex Forte, Vitamin A and D Concentrate, Folgard RX, Folplex, Vol-Care Rx, Foltanx RF, Virt-Caps, Therems, Childrens Chewable Multivitamins, Balanced B-50, Vitacirc-B, Essential Balance, Fruity Chew, Flintstones with C Multivitamins, Poly Vit Drops, Mynephron, Celebrate B-12, Apetigen, Stress Formula, Vitamin C, E, and Rose Hips, Mega B, L-methylfolate Ca, Me-Cbl NAC, Theragenerix, Cernevit, MTX Support, Cardiotek, Bugs Bunny Multiple Vitamins, Infuvite Pediatric, Vitamin A, D, Folastin, Levomefolate Calcium-Algal Powder, Folbee Plus, Folcaps, Abidec, Topfit Vitamin B Complex, Vitamin B Compound Strong, Jetepar, Centrum 8400, Folbalin, Foltabs 800, One-A-Day Men's Health Formula, Daily-Vite Men's Formula, Biotin Forte, B 100 Complex, B-Plex, Vitaplex, Tri-Vi-Sol, Metafolbic, Metafolbic Plus, Lipogen, Virt-Vite, Virt-Vite Forte, Stress-600, 1000 BC, Neurodep, Cefol, Protegra, Watkins Harvest, Balanced B-100, B-Scorbic, Bee with C, Nat-Rul B-125, Balanced B-150, Unicap Capsule, Unicap Jr, Unicap, Optilets-500, Super Plenamins, Vitamins for Hair, One-A-Day Essentials, Vi-Daylin Chewable, Folast, Enfolast, Sunkist Child Chewable with C, Enfolast-N, Sunkist Child Chewable, Poly-Vi-Sol Chewable, Neurpath-B, Triphro, Poly-Vit Chew, Vita-Respa, Bugs Bunny with Extra C, Geravine, Bounty Bear Vitamins, Garfield Vitamins, Vi-Daylin Drops, Poly-Vi-Sol Drops, Baby Vitamin Drop, Vita Drop, MVC SDV, Glutofac, Allbee-C, Vitabee with C, Stress B with C, High Potency B+C, Av-VITE FB, Farbee with C, Renatabs, Tri-Vitamin, DEKAs Essential, Vitamin B-50, Folika-T, Vitamin B-100, D-400 international units, Vitamin B-100 T/R, Hexavitamin, Kenwood Therapeutic, Theravite, Thera-Plus, Oncovite, Glycogenics, Beminal-500, High Potency B Complex with B12 and C, Super B-100 TD, Tri-Vit Drops, Flintstones Toddler, One Tab Daily, Stress Formula 600, Tri-Vit, Apatate, T-Vites, High B Complex, L-methylfolate Ca, P-5-P, Me-Cbl, Beminal, Beminal with C Fortis, Full Spectrum B with C, Allbee with C, Prevital, Surbex Filmtab, Tender Age Vitamin ADC, Folgard Rx 2.2, Cernevit-12, SeroSyn, Diatx, Thex Forte, Metafolbic Plus RF, Dosoquin, Protegra Cardio, Virt-Vite Plus, K2 Plus D3, Vitamin Daily Liquid, Renaphro, Apetex, Virt-Gard, Dialyvite Rx, L-Methyl-MC, VP-Vite Rx, Vesselvite, Combgen, Unichem Multivitamin, L-Methyl-B6-B12, Health Aid Multivitamin, AllanTex, One Daily Multi-Essential, Larobec, Cardiotek Rx, Folbalin Plus, Dialyvite 800, Multi-Delyn, Multi Vits with Beta Carotene, Foleve Plus, Folnate, Folnate Plus, B-Complex with B-12, Foleve, Hair, Skin, & Nails Gummies, Folamin, DexFol, Equaline One Daily Essential, Menopause Relief with Lifenol, Av-VITE FB Forte, Folmor, Zycose, Vigomar Forte, Allbee Plus, Vimar, Triveen-CF, Nature's Bounty Hair Skin & Nails, Folbic RF, Total B with C, Methaver, GNC Women's Hair, Skin & Nails Formula, Folbee AR, NuFol, Co-Veratrol, Mebolex, Methazel, Dyzbac, Mynephrocaps, Nufola, Omega Q Plus, Acnepril, Super Theravite-M, Primaplex, Becomject-100, Poly-Vita Drops, MVI-12, B-Ject 100, L-Methyl-MC NAC, Therobec, Formula B, Vi-Daylin ADC, Nephrocaps QT, Lipotriad, Folplex 2.2, Cholinoid, Tri-Vita Drops, Thera-Tabs, Liponol, Bee-Comp with C, Cholidase, Vita-Plus G, Rovin-CF, Cota-B-Plex, Neuroforte-Six, MVI Pediatric, B-Plex Plus, Nephrolan Rx, Ivites Rx, Zymacap, Vi-Daylin, Dayalets, Sigtab, Allbee-C 800, B-Complex SR, Wellesse Sugar Free Childrens Multivitamin Gummies, Alz-Nac, Sesame St Vitamins with Extra C, Surbex-T, Male Formula, Superplex-T, Vi-Stress, T-BMP, Animal Shape Vitamins, B-50 Complex, Niva-Fol)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Pepto-Bismol (bismuth subsalicylate)
  • prednisone (Deltasone, Rayos, Sterapred, Sterapred DS, Prednicot, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • Prilosec (omeprazole)
  • Synthroid (levothyroxine)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Larapam SR, Tramedo, Ryzolt, GenRx Tramadol, ConZip, Zydol, Tramal SR, Tramahexal, Zamadol, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • Tylenol (acetaminophen)
  • Viberzi (eluxadoline)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • warfarin (Coumadin, Jantoven)
  • Xanax (alprazolam)
  • Zantac (ranitidine)
  • Zofran (ondansetron)
  • Zoloft (sertraline)
  • Zyrtec (cetirizine)

Imodium (loperamide) alcohol/food interactions

There is 1 alcohol/food interaction with Imodium (loperamide)

Imodium (loperamide) disease interactions

There is 1 disease interaction with Imodium (loperamide):

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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