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Imodium (loperamide) Drug Interactions

A total of 651 drugs are known to interact with Imodium (loperamide).

  • 58 major drug interactions
  • 592 moderate drug interactions
  • 1 minor drug interaction

Show all medications in the database that may interact with Imodium (loperamide).

Check for interactions

Type in a drug name to check for interactions with Imodium (loperamide).

Most frequently checked interactions

View interaction reports for Imodium (loperamide) and the medicines listed below.

  • acetaminophen (Tylenol, Paracetamol, Panadol, Mapap, Tylenol Arthritis Pain, Tylenol Extra Strength, Ofirmev, Perfalgan, Arthritis Pain Relief, Efferalgan, Dafalgan, Tempra, Children's Tylenol, Doliprane, Paracetamol Teva, Feverall, Cetafen, Altenol, Cipla Genpharm Paracetamol, Paracetamol Almus, Lemsip Max, Paracetamol Ranbaxy, Infant's Tylenol, Tactinal, Panadol ActiFast, Promax, Tylenol 8 Hour, Lemsip Original, Panadol Soluble, Aceta, Pharbetol, Calpol Paediatric, Panadol Osteo, Mapap Arthritis Pain, Panadol Gel Tabs, Tylophen, Genapap, Pain Clear Paracetamol, Setamol, Blooms the Chemist Paracetamol, Capital Chemist Paracetamol, Acephen, Panadol Childrens, Buckley's Complete, Taminol, Efferalgan Pediatrique, Paracetamol Ivax, Actamin, BF-Paradac, Paracetamol Sandoz, Paracetamol Sandoz Conseil, Tycolene, Atasol, Acetaminophen-odan, Mapap Extra Strength Rapid Burst, Disprol Soluble Paracetamol, Calpol Fastmelts, Aminofen, Hedex, Valorin, Miradol, Parmol, Orajel Maximum Strength Toothache, Paraspen, RP Scherer Paracetamol, Terry White Chemists Paracetamol, Pharmacist Advice Paracetamol, Terry White Chemists Paracetamol Colourfree Children 5-12 Years, Paracare, Tylenol Childrens Paracetamol, Conney Aspirin-Free, Priceline Paracetamol, Panadol Gel Caps, Pacimol Caplets, Pharmore Paracetamol, Basics Paracetamol, Sigma Pain Relief, Paraspen Drops, Panadol Colourfree Drops, Pharmacist Paracetamol Infant Drops, Pharmacist Paracetamol Infant Drops Colour Free, Bi-Lo Paracetamol, Pain-Eze Paracetamol Infant Drops Colour Free, Pharmaction Paracetamol, Biochemie Paracetamol, Healthsense Pain Relief Drops Children 1 Month to 2 Years, Black And Gold Paraceatmol, Pharmacist Advice Paracetamol Infant Drops, Black and Gold Paracetamol, Hexal Comfarol, Panadol Extend, Abenol, Paracetamol Soluble, Vitapap, Bristol Pharma Paracetamol, Sigma Paracetamol, Actimol Infant, ConRx Extra Strength, PediaCare Infants' Acetaminophen Fever Reducer/Pain Reliever, PediaCare Children's Acetaminophen Fever Reducer/Pain Reliever, Pharmacy Health Paracetamol Colour Free Childrens, PediaCare Smooth Melts Acetaminophen Fever Reducer/Pain Reliever, Pharmacy Health Paracetamol Colour Free Infants and Childrens Drops 1 Month-4 Years, Mapap Children's, Lemsip Cold and Flu Liquid Capsule, Children's Silapap, Febrol Solution, Pharmacy Health Own Name Paracetamol for Children, Febridol Infant Drops, Accidental Rapatabs, Chem Mart Chemadol Children 1 to 5 Years, Chem Mart Chemadol Colourfree, Chem Mart Chemadol Colourfree Children 5-12 Years, Chemists Own Chiildrens Paracetamol 5-12 Years, Lemsip Headcold, Chemists Own Childrens Paracetamol 1-5 Years, Chemists Own Paracetamol, Chemists Own Paracetamol Capseals, Chemists Own Paracetamol Pain & Fever 1 Month to 2 Years, Chemists Own Paracetamol Pain & Fever 1 to 5 Years, Chemists Own Paracetamol Pain and Fever 5 to 12 Years, A-Pak Laboratories Paediatric Analgesic Paracetamol, Chemplus Paracetamol, Chemworld Colourfree Childrens Paracetamol Double Strength 5-12 Years, Chemworld Colourfree Childrens Paracetamol Junior 1-5 Years, Chemworld Paracetamol, Chemworld Paracetamol Infant Colour Free, HyVee Health 8 Hour Pain Relief, Bydol, Chem Mart Chemadol, Leader 8 Hour Pain Reliever, Children's ElixSure, Little Fevers, Mapap Rapid Release Gelcaps, Benylin Sore Throat, Fawns & McAllan Paracetamol, Zee Unaspirin ES, Chem Mart Chemadol Colourfree Childrens 1-5 Years, Midol Long Lasting Relief, Childrens Panadol 1 - 5 Years Colourfree, Childrens Panadol 1 - 5 Years, Childrens Panadol 5 - 12 Years Colourfree, Childrens Panadol 5 - 12 Years, Equaline Pain Relief, Help I Have A Headache, Febridol Clear Effervescent, Herron Paracetamol Tabsules, Panadol Rapid Handipak, Paralgin Paracetamol Tabsules, Pharmacist Childrens Paracetamol Colourfree 1-5 Years, Pharmacist Childrens Paracetamol Colourfree 5-12 Years, Pharmacy Health Colour Free Childrens Paracetamol, Gold Cross Paracetamol, Tylenol Cold Sore Throat, Alpha First Aid Supplies Paracetamol, Guardian Childrens Paracetamol 5-12 Years, Guardian Paracetamol, Guardian Paracetamol Tabsules, Rex Paracetamol, Topcare Arthritis Pain Relief, Accidental First Aid Supplies Paracetamol, Panadol Jr, Flu Strength Hot Lemon Powders, Paineze Paracetamol, Health Care Chemist Paracetamol Infant Drops Colour Free, Genebs, Herron Gold Paracetamol Tabsules, Tylenol Regular Strength, Panamol, Herron Paracetamol, Tempra 2, Tempol, Herron Paracetamol Capseals, Tempra 3, Herron Paracetamol Capseals Handy Pack, Herron Paracetamol Handy Pack, Apra, Q-Nol, Claradol, Anacin Aspirin Free, Conacetol, Dolono, Doliprane Adultes, Coles Paracetamol, Genapap Extra Strength, Doliprane Sans Sucre, Dolitabs, Home Brand Paracetamol, Q-Pap Extra Strength, Dolko, ICN Paracetamol, Redutemp, Dolko Enfants, Dolotec, Vicks Formula 44 Custom Care Body Aches, James Dean Pharmacy Paracetamol, Pain-Eze, Uniserts, Efferalganodis, Silapap Childrens, Expandox, Dolono Infant, Geluprane, Paracetamol Arrow, Paracetamol Biogaran, Ed-APAP, Paracetamol EG, St. Joseph Aspirin-Free, Country Chemists Paracetamol, Paracetamol Merck, Liquiprin, Paracetamol Qualimed, Adprin B, Paracetamol RPG, DG Health Pain Reliever, Tempra Quicklets, Lloydspharmacy Paracetamol Six Plus, Q-Pap, Paracetamol Winthrop, Triaminic Fever Reducer Pain Reliever, Lloydspharmacy Paracetamol Infant, Paracetamol Zydus, Triaminic Infant Drops, Atasol Forte, Paralyoc, Tylenol Cool Caplet Extra Strength, Perfalgan Nourrissons Et Enfants, Mapap Rapid Tabs, Jr. Tylenol, Elixsure Fever/Pain, Infadrops, Calpol Infant, Disprol Paracetamol, Galpamol, Paldesic, Medinol Paediatric, Medinol Under 6, Alvedon, Infantaire Drops, Lemsip Pharmacy Non-Decongestant Formula, Calpol Six Plus, Masophen, Medinol Over 6, Nortemp Children's, Paracets, Anadin Paracetamol, UN-Aspirin Extra Strength, Mandanol, Actimol Children's, Dakota Paracetamol, Umphamol, Remedol, Panamax, Panamax 240, Paralgin, Parahexal, Febridol, Mid West Products Numol Paracetamol, Silapap Infants, Cuprofen for Children, Mapap Infant Drops, Mandanol Infant, Cetafen Extra, Mandanol 6+, Lemsip Childrens Cold & Flu, Fennings Childrens Cooling, Duatrol SR, Aldi Hedanol Paracetamol, Under Ten Care Infant, Alphapharm Paracetamol, Amadol Paracetamol, No Frills Paracetamol, Tylenol Sore Throat Daytime, Nova Paracetamol, Mapap Meltaway, Numark Paracetamol, Amcal Childrens Paracetamol 1-5 Years, Nyal Paracetamol, Medi-Tabs, Amcal Childrens Paracetamol 5-12 Years, Amcal Paracetamol Pain Relief, Ordov Febrigesic Paracetamol, Topcare 8 Hour Pain Relief, Amcal Paracetamol Infant Drops 1 Month to 2 Years, Pain-Eze Paracetamol Infant Drops, Febridol Syrup for Children, Amcal Paracetamol Tabsules, Pharmacist Advice Colourfree Childrens Paracetamol Double Strength, Guardian Childrens Paracetamol, Pharmacist Formula Paracetamol, Pharmacist Formula Infants, RP Scherer Paracetamol Liquid-Filled Capsules, Savings Paracetamol, Signature Range Paracetamol, Dymadon, Soul Pattinson Childrens Paracetamol Elixir, Soul Pattinson Colour Free Paracetamol 1-5 Years, Soul Pattinson Colour Free Paracetamol Drops, Soul Pattinson Colourfree Childrens Paracetamol, API Healthcare Coloufree Childrens Paracetamol, Soul Pattinson Paracetamol, API Healthcare Colourfree Childrens Paracetamol Double Strength, Soul Pattinson Paracetamol Clear Effervescent, Panadol Mini Caps, API Healthcare Paracetamol, Pharmacy Health Paracetamol, Terry White Chemists Colour Free Paracetamol 1-5 Years, Pharmacist Paracetamol, Terry White Chemists Colour Free Paracetamol Infant Drops)
  • Advil (ibuprofen)
  • aspirin (Aspir 81, Ecotrin, Aspirin Low Strength, Acetylsalicylic Acid, Bayer Aspirin, Aspir-Low, Bufferin, Ascriptin, Arthritis Pain, Aspiritab, Aspergum, Fasprin, Halfprin, Easprin, Ecotrin Adult Low Strength, Empirin, Migralex, Aspi-Cor, St. Joseph 81 mg Chewable Aspirin, Bayer Children's Aspirin, Buffered Aspirin, Durlaza, Ecotrin Maximum Strength, Entercote, Bufferin Extra Strength, Ascriptin Enteric, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Bayer Aspirin Regimen, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspirtab, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Low Dose ASA, Bayer Aspirin Extra Strength Plus, Buffex, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Therapy Bayer, St. Joseph Aspirin, Stanback Analgesic, Norwich Aspirin, Acuprin 81, Ecpirin, Bayer Women's Aspirin With Calcium, Zero-Order Release, YSP Aspirin, Miniprin, Aspirin Lite Coat, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Augmentin (amoxicillin / clavulanate)
  • azithromycin (Zithromax, Azithromycin Dose Pack, Z-Pak, Zmax)
  • Benadryl (diphenhydramine)
  • Cipro (ciprofloxacin)
  • dicyclomine (Bentyl, Dicyclocot, Bentyl Syrup, Bemote, Byclomine, Di-Spaz, Dibent, Dilomine)
  • doxycycline (Vibramycin, Oracea, Monodox, Doxy 100, Doryx, Adoxa, Targadox, Morgidox, Acticlate, Vibra-Tabs, Doxy-Caps, Periostat, Doxy 200, Oraxyl, Doryx MPC, Doxy-D, Alodox, Adoxa Pak, Avidoxy, Adoxa TT, Adoxa CK, Ocudox, LymePak, Uracil, Mondoxyne NL, NicAzel Doxy, Doxy-Lemmon)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Children's Motrin, Proprinal, Advil Liqui-Gels, Ibu-8, Motrin IB, Motrin Childrens, Rufen, Childrens Ibuprofen Berry, IBU-200, Ibuprofen PMR, Advil Migraine, Ibu-Tab, Genpril, Menadol, Advil Children's, Midol Maximum Strength Cramp Formula, Motrin Migraine Pain, Addaprin, Motrin Infant Drops, NeoProfen, Caldolor, Motrin Pediatric, Haltran, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, A-G Profen, Nuprin, Advil Junior Strength, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Advil Infant's Concentrated Drops, Cap-Profen, Advil Film-Coated)
  • Lasix (furosemide)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Euthyrox, Unithroid, Levothyrox, Eutroxsig, Levo-T, Oroxine, L Thyroxine Roche, Levotabs, Novothyrox, Tirosint-Sol, Levotec, Evotrox)
  • Lexapro (escitalopram)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • Lomotil (atropine / diphenoxylate)
  • metformin (Glucophage, Glumetza, Glucophage XR, Fortamet, Riomet)
  • metoprolol (Metoprolol Tartrate, Metoprolol Succinate ER, Toprol-XL, Lopressor, Kapspargo Sprinkle)
  • multivitamin (Daflon, Metanx, Neurobion, Vitamins, Theragran, Vitamin B Complex 100, Cerefolin NAC, Cerefolin, Rena-Vite, Folbic, Foltx, Estroven, Nephro-Vite, Lipoflavonoid, Folbee, Foltanx, Thera, Super B Complex, MVI Adult, Nephrocaps, PoDiaPN, Folic Acid XTRA, Tab-A-Vite, Cod Liver Oil Mint, B Complex 100, Triphrocaps, FaBB, Nufola, Nephro-Vite Rx, Cod Liver Oil, Multi Vitamin+, Rheumate, Renal Caps, Essentiale, Berocca, Daily Vite, Rena-Vite Rx, Xyzbac, Lysiplex, Flintstones Multivitamins, Surbex, Super B-50, Fletanol, Infuvite, Infuvite Pediatric, Folcaps, Folinic-Plus, StressTabs, Reno Caps, Surbex with C, Folika-T, Apetigen, Stress Formula, B Complex 50, Cernevit, Vitamin Daily Liquid, Topfit Vitamin B Complex, Vitamin B Compound Strong, Nephronex, Folgard RX, One-A-Day Men's Health Formula, Folplex, Nephplex Rx, Metafolbic Plus, Virt-Caps, Therems, Daily Multiple Vitamins, Childrens Chewable Multivitamins, Vitacirc-B, One-A-Day Essentials, Essential Balance, Flintstones with C Multivitamins, Stress B with C, Theravite, Thera-Plus, High Potency B Complex with B12 and C, Super B-100 TD, L-methylfolate Ca, Me-Cbl NAC, Theragenerix, Apetex, Folastin, Topfit Vitamin B Complex Forte, L-Methyl-B6-B12, Jetepar, Vitamin A and D Concentrate, Centrum 8400, Foltabs 800, Menopause Relief with Lifenol, Daily-Vite Men's Formula, Biotin Forte, Vimar, B 100 Complex, Vol-Care Rx, Folbic RF, Foltanx RF, Mebolex, Mebolic, B-Plex, Vitaplex, Metafolbic, Stress-600, Thera-Tabs, Vi-Daylin, Poly-Vi-Sol, Watkins Harvest, Balanced B-100, B-Stress, B-Scorbic, Bee with C, Balanced B-50, Nat-Rul B-125, Balanced B-150, Unicap Capsule, Unicap Jr, Unicap, Optilets-500, Super Plenamins, Vitamins for Hair, Vi-Daylin Chewable, Folast, Enfolast, Sunkist Child Chewable with C, Enfolast-N, Sunkist Child Chewable, Poly-Vi-Sol Chewable, Neurpath-B, Fruity Chew, Triphro, Poly-Vit Chew, Vita-Respa, Chewable-Vite, Bugs Bunny with Extra C, Geravine, Bounty Bear Vitamins, Garfield Vitamins, Vi-Daylin Drops, Poly-Vi-Sol Drops, Baby Vitamin Drop, Vita Drop, Poly Vit Drops, MVC SDV, Glutofac, Allbee-C, Vitabee with C, High Potency B+C, Av-VITE FB, Farbee with C, Mynephron, Renatabs, Tri-Vitamin, DEKAs Essential, Vitamin B-50, Vitamin B-100, D-400 international units, Vitamin B-100 T/R, Hexavitamin, Celebrate B-12, Kenwood Therapeutic, Oncovite, Glycogenics, Beminal-500, Tri-Vit Drops, Flintstones Toddler, One Tab Daily, Vitamin C, E, and Rose Hips, Scotts Emulsion, Stress Formula 600, Tri-Vit, Mega B, Apatate, T-Vites, Hylavite, High B Complex, L-methylfolate Ca, P-5-P, Me-Cbl, Prostate 2.4, MTX Support, Cardiotek, Beminal, Beminal with C Fortis, Full Spectrum B with C, Bugs Bunny Multiple Vitamins, Allbee with C, Prevital, Surbex Filmtab, Tender Age Vitamin ADC, Folgard Rx 2.2, Cernevit-12, SeroSyn, Diatx, Vitamin A, D, One-A-Day 50+, Thex Forte, Metafolbic Plus RF, Dosoquin, Protegra Cardio, Virt-Vite Plus, K2 Plus D3, Renaphro, Virt-Gard, Dialyvite Rx, L-Methyl-MC, Levomefolate Calcium-Algal Powder, VP-Vite Rx, Vesselvite, Folbee Plus, Combgen, Abidec, Unichem Multivitamin, Health Aid Multivitamin, AllanTex, One Daily Multi-Essential, Larobec, Foltrate, Cardiotek Rx, Folbalin Plus, Dialyvite 800, Folbalin, Multi-Delyn, Multi Vits with Beta Carotene, Foleve Plus, Folnate, Folnate Plus, B-Complex with B-12, Foleve, Hair, Skin, & Nails Gummies, Folamin, DexFol, Equaline One Daily Essential, Av-VITE FB Forte, Folmor, Zycose, Vigomar Forte, Allbee Plus, Triveen-CF, Nature's Bounty Hair Skin & Nails, Total B with C, Methaver, GNC Women's Hair, Skin & Nails Formula, Folbee AR, NuFol, Co-Veratrol, Methazel, Dyzbac, Mynephrocaps, Omega Q Plus, Acnepril, Super Theravite-M, Primaplex, Becomject-100, Poly-Vita Drops, MVI-12, B-Ject 100, L-Methyl-MC NAC, Therobec, Formula B, Tri-Vi-Sol, TL Gard, Vi-Daylin ADC, Lipogen, Nephrocaps QT, Virt-Vite, Lipotriad, Virt-Vite Forte, Folplex 2.2, Cholinoid, Tri-Vita Drops, Liponol, Bee-Comp with C, Cholidase, Vita-Plus G, Rovin-CF, Cota-B-Plex, 1000 BC, Neurodep, Neuroforte-Six, MVI Pediatric, B-Plex Plus, Nephrolan Rx, Ivites Rx, Zymacap, Dayalets, Sigtab, Allbee-C 800, Cefol, B-Complex SR, Protegra, Wellesse Sugar Free Childrens Multivitamin Gummies, Alz-Nac, Sesame St Vitamins with Extra C, Surbex-T, Male Formula, Superplex-T, Vi-Stress, T-BMP, Animal Shape Vitamins, B-50 Complex, Niva-Fol)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Pepto-Bismol (bismuth subsalicylate)
  • prednisone (Deltasone, Rayos, Sterapred, Prednicot, Sterapred DS, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • Prilosec (omeprazole)
  • Synthroid (levothyroxine)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, ConZip, Zydol, Tramal SR, GenRx Tramadol, Zamadol, Ryzolt, Tramedo, Larapam SR, Tramahexal SR, Tramahexal, Zydol XL, Rybix ODT, Ultram ODT)
  • Tylenol (acetaminophen)
  • Viberzi (eluxadoline)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • warfarin (Coumadin, Jantoven)
  • Xanax (alprazolam)
  • Zantac (ranitidine)
  • Zofran (ondansetron)
  • Zoloft (sertraline)
  • Zyrtec (cetirizine)

Imodium (loperamide) alcohol/food interactions

There is 1 alcohol/food interaction with Imodium (loperamide)

Imodium (loperamide) disease interactions

There is 1 disease interaction with Imodium (loperamide):

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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