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Imodium (loperamide) Drug Interactions

A total of 645 drugs are known to interact with Imodium (loperamide).

  • 58 major drug interactions
  • 586 moderate drug interactions
  • 1 minor drug interaction

Show all medications in the database that may interact with Imodium (loperamide).

Check for interactions with Imodium (loperamide)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Imodium (loperamide)

  • acetaminophen (Tylenol, Paracetamol, Mapap, Panadol, Tylenol Arthritis Pain, Tylenol Extra Strength, Ofirmev, Children's Tylenol, Dafalgan, Paracetamol Almus, Perfalgan, Tempra, Doliprane, Paracetamol Teva, Panadol Osteo, Arthritis Pain Relief, Aceta, Tactinal, Cipla Genpharm Paracetamol, Alvedon, Panadol ActiFast, Tylenol 8 Hour, Panadol Extend, Efferalgan, Paracetamol Arrow, Liquiprin, Infant's Tylenol, Aminofen, Miradol, Panamax, Paracare, Priceline Paracetamol, Tylophen, Abenol, Febrol Solution, Pharmacy Health Own Name Paracetamol for Children, Little Fevers, Pharbetol, Q-Nol, Pain-Eze, Actamin, DG Health Pain Reliever, Paracetamol Sandoz, Tycolene, Perfalgan Nourrissons Et Enfants, Calpol Infant, Calpol Paediatric, Cetafen, Calpol Fastmelts, Mandanol, Valorin, Remedol, Promax, API Healthcare Paracetamol, Terry White Chemists Paracetamol, Pharmacist Advice Paracetamol, Terry White Chemists Paracetamol Colourfree Children 5-12 Years, Tylenol Childrens Paracetamol, Conney Aspirin-Free, Panadol Gel Caps, Pacimol Caplets, Pharmore Paracetamol, Basics Paracetamol, Genapap, Sigma Pain Relief, Pain Clear Paracetamol, Setamol, Paraspen Drops, Panadol Colourfree Drops, Pharmacist Paracetamol Infant Drops, Pharmacist Paracetamol Infant Drops Colour Free, Bi-Lo Paracetamol, Pain-Eze Paracetamol Infant Drops Colour Free, Pharmaction Paracetamol, Biochemie Paracetamol, Healthsense Pain Relief Drops Children 1 Month to 2 Years, Black And Gold Paraceatmol, Pharmacist Advice Paracetamol Infant Drops, Black and Gold Paracetamol, Hexal Comfarol, Blooms the Chemist Paracetamol, Paracetamol Soluble, Vitapap, Bristol Pharma Paracetamol, Sigma Paracetamol, Actimol Infant, ConRx Extra Strength, PediaCare Infants' Acetaminophen Fever Reducer/Pain Reliever, PediaCare Children's Acetaminophen Fever Reducer/Pain Reliever, Pharmacy Health Paracetamol Colour Free Childrens, PediaCare Smooth Melts Acetaminophen Fever Reducer/Pain Reliever, Pharmacy Health Paracetamol Colour Free Infants and Childrens Drops 1 Month-4 Years, Altenol, Mapap Children's, Capital Chemist Paracetamol, Lemsip Cold and Flu Liquid Capsule, Children's Silapap, Febridol Infant Drops, Accidental Rapatabs, Chem Mart Chemadol Children 1 to 5 Years, Chem Mart Chemadol Colourfree, Chem Mart Chemadol Colourfree Children 5-12 Years, Chemists Own Chiildrens Paracetamol 5-12 Years, Lemsip Headcold, Chemists Own Childrens Paracetamol 1-5 Years, Lemsip Max, Chemists Own Paracetamol, Lemsip Original, Chemists Own Paracetamol Capseals, Chemists Own Paracetamol Pain & Fever 1 Month to 2 Years, Chemists Own Paracetamol Pain & Fever 1 to 5 Years, Chemists Own Paracetamol Pain and Fever 5 to 12 Years, A-Pak Laboratories Paediatric Analgesic Paracetamol, Chemplus Paracetamol, Chemworld Colourfree Childrens Paracetamol Double Strength 5-12 Years, Chemworld Colourfree Childrens Paracetamol Junior 1-5 Years, Chemworld Paracetamol, Chemworld Paracetamol Infant Colour Free, HyVee Health 8 Hour Pain Relief, Bydol, Chem Mart Chemadol, Leader 8 Hour Pain Reliever, Children's ElixSure, Mapap Rapid Release Gelcaps, Benylin Sore Throat, Fawns & McAllan Paracetamol, Zee Unaspirin ES, Chem Mart Chemadol Colourfree Childrens 1-5 Years, Midol Long Lasting Relief, Childrens Panadol 1 - 5 Years Colourfree, Childrens Panadol 1 - 5 Years, Childrens Panadol 5 - 12 Years Colourfree, Childrens Panadol 5 - 12 Years, Equaline Pain Relief, Help I Have A Headache, Febridol Clear Effervescent, Herron Paracetamol Tabsules, Panadol Rapid Handipak, Panadol Soluble, Paralgin Paracetamol Tabsules, Pharmacist Childrens Paracetamol Colourfree 1-5 Years, Pharmacist Childrens Paracetamol Colourfree 5-12 Years, Pharmacy Health Colour Free Childrens Paracetamol, Gold Cross Paracetamol, Tylenol Cold Sore Throat, Alpha First Aid Supplies Paracetamol, Guardian Childrens Paracetamol 5-12 Years, Guardian Paracetamol, Guardian Paracetamol Tabsules, Acephen, Rex Paracetamol, Feverall, Topcare Arthritis Pain Relief, Accidental First Aid Supplies Paracetamol, Panadol Childrens, Panadol Jr, Flu Strength Hot Lemon Powders, Paineze Paracetamol, Health Care Chemist Paracetamol Infant Drops Colour Free, Genebs, Buckley's Complete, Herron Gold Paracetamol Tabsules, Tylenol Regular Strength, Panamol, Herron Paracetamol, Tempra 2, Tempol, Herron Paracetamol Capseals, Tempra 3, Taminol, Herron Paracetamol Capseals Handy Pack, Herron Paracetamol Handy Pack, Apra, Claradol, Anacin Aspirin Free, Conacetol, Dolono, Doliprane Adultes, Coles Paracetamol, Genapap Extra Strength, Doliprane Sans Sucre, Dolitabs, Home Brand Paracetamol, Q-Pap Extra Strength, Dolko, ICN Paracetamol, Redutemp, Dolko Enfants, Dolotec, Vicks Formula 44 Custom Care Body Aches, James Dean Pharmacy Paracetamol, Efferalgan Pediatrique, Uniserts, Efferalganodis, Silapap Childrens, Expandox, Dolono Infant, Geluprane, Paracetamol Biogaran, Ed-APAP, Paracetamol EG, St. Joseph Aspirin-Free, Country Chemists Paracetamol, Paracetamol Ivax, Paracetamol Merck, Paracetamol Qualimed, Paracetamol Ranbaxy, Adprin B, BF-Paradac, Paracetamol RPG, Tempra Quicklets, Paracetamol Sandoz Conseil, Lloydspharmacy Paracetamol Six Plus, Q-Pap, Paracetamol Winthrop, Triaminic Fever Reducer Pain Reliever, Lloydspharmacy Paracetamol Infant, Atasol, Paracetamol Zydus, Triaminic Infant Drops, Atasol Forte, Paralyoc, Tylenol Cool Caplet Extra Strength, Acetaminophen-odan, Mapap Rapid Tabs, Jr. Tylenol, Mapap Extra Strength Rapid Burst, Elixsure Fever/Pain, Infadrops, Disprol Soluble Paracetamol, Disprol Paracetamol, Galpamol, Paldesic, Medinol Paediatric, Medinol Under 6, Infantaire Drops, Lemsip Pharmacy Non-Decongestant Formula, Calpol Six Plus, Masophen, Medinol Over 6, Nortemp Children's, Paracets, Anadin Paracetamol, Hedex, UN-Aspirin Extra Strength, Actimol Children's, Dakota Paracetamol, Umphamol, Panamax 240, Paralgin, Parahexal, Febridol, Mid West Products Numol Paracetamol, Parmol, Silapap Infants, Cuprofen for Children, Mapap Infant Drops, Mandanol Infant, Cetafen Extra, Mandanol 6+, Lemsip Childrens Cold & Flu, Fennings Childrens Cooling, Duatrol SR, Aldi Hedanol Paracetamol, Under Ten Care Infant, Alphapharm Paracetamol, Amadol Paracetamol, No Frills Paracetamol, Tylenol Sore Throat Daytime, Nova Paracetamol, Mapap Meltaway, Numark Paracetamol, Amcal Childrens Paracetamol 1-5 Years, Nyal Paracetamol, Medi-Tabs, Amcal Childrens Paracetamol 5-12 Years, Orajel Maximum Strength Toothache, Mapap Arthritis Pain, Amcal Paracetamol Pain Relief, Ordov Febrigesic Paracetamol, Topcare 8 Hour Pain Relief, Amcal Paracetamol Infant Drops 1 Month to 2 Years, Pain-Eze Paracetamol Infant Drops, Febridol Syrup for Children, Amcal Paracetamol Tabsules, Pharmacist Advice Colourfree Childrens Paracetamol Double Strength, Guardian Childrens Paracetamol, Pharmacist Formula Paracetamol, Pharmacist Formula Infants, Paraspen, RP Scherer Paracetamol, RP Scherer Paracetamol Liquid-Filled Capsules, Savings Paracetamol, Signature Range Paracetamol, Dymadon, Soul Pattinson Childrens Paracetamol Elixir, Soul Pattinson Colour Free Paracetamol 1-5 Years, Soul Pattinson Colour Free Paracetamol Drops, Soul Pattinson Colourfree Childrens Paracetamol, Panadol Gel Tabs, API Healthcare Coloufree Childrens Paracetamol, Soul Pattinson Paracetamol, API Healthcare Colourfree Childrens Paracetamol Double Strength, Soul Pattinson Paracetamol Clear Effervescent, Panadol Mini Caps, Pharmacy Health Paracetamol, Terry White Chemists Colour Free Paracetamol 1-5 Years, Pharmacist Paracetamol, Terry White Chemists Colour Free Paracetamol Infant Drops)
  • Advil (ibuprofen)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Arthritis Pain, Fasprin, Ecotrin Adult Low Strength, Low Dose ASA, Bufferin, Aspiritab, Aspirin Lite Coat, Easprin, Bayer Children's Aspirin, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Bayer Aspirin Regimen, Aspirtab, Halfprin, Aspergum, Durlaza, Acuprin 81, Miniprin, Bufferin Low Dose, Empirin, Buffered Aspirin, Entercote, St. Joseph Aspirin, Ascriptin Enteric, Ecpirin, Bayer Women's Aspirin With Calcium, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Aspi-Cor, Medi-Seltzer, Sloprin, St. Joseph 81 mg Chewable Aspirin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Ecotrin Maximum Strength, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Bufferin Extra Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Zero-Order Release, YSP Aspirin, Migralex, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Augmentin (amoxicillin / clavulanate)
  • azithromycin (Zithromax, Azithromycin Dose Pack, Z-Pak, Zmax)
  • Benadryl (diphenhydramine)
  • Cipro (ciprofloxacin)
  • dicyclomine (Bentyl, Dicyclocot, Bentyl Syrup, Byclomine, Bemote, Di-Spaz, Dibent, Dilomine)
  • doxycycline (Vibramycin, Doxy 100, Oracea, Doryx, Monodox, Vibra-Tabs, Adoxa, Acticlate, Periostat, Alodox, Doxy-D, Oraxyl, Morgidox, Adoxa Pak, Avidoxy, Targadox, Uracil, Doryx MPC, Doxy-Caps, Adoxa TT, Adoxa CK, Ocudox, LymePak, Mondoxyne NL, NicAzel Doxy, Doxy-Lemmon, Doxy 200)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Advil Infant's Concentrated Drops, Children's Motrin, Advil Children's, Ibu-8, Ibuprofen PMR, Caldolor, Motrin Childrens, Motrin Migraine Pain, Addaprin, Ibu-4, Ibu-Tab, Rufen, Midol IB, A-G Profen, Childrens Ibuprofen Berry, Advil Migraine, Ibu-6, Motrin Infant Drops, NeoProfen, Genpril, Haltran, Menadol, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • Lasix (furosemide)
  • levothyroxine (Synthroid, Levoxyl, Tirosint, Levothroid, Eltroxin, Levothyrox, Unithroid, Euthyrox, Levo-T, L Thyroxine Roche, Novothyrox, Levotabs, Oroxine, Eutroxsig, Tirosint-Sol, Levotec, Evotrox)
  • Lexapro (escitalopram)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • Lomotil (atropine / diphenoxylate)
  • metformin (Glucophage, Glumetza, Glucophage XR, Riomet, Fortamet)
  • multivitamin (Metanx, Daflon, Rena-Vite, Folbic, Theragran, Estroven, Nephro-Vite, Cerefolin, Neurobion, Folbee, Nephrocaps, Lipoflavonoid, Vitamins, B Complex 100, Vitamin B Complex 100, Foltx, Multi Vitamin+, Foltanx, Cod Liver Oil, Cod Liver Oil Mint, Super B Complex, Daily Multiple Vitamins, Folic Acid XTRA, Thera, PoDiaPN, Tab-A-Vite, Triphrocaps, Renal Caps, Infuvite, Rena-Vite Rx, Nephplex Rx, Chewable-Vite, Cerefolin NAC, Rheumate, Folinic-Plus, Foltrate, Folgard RX, Xyzbac, Berocca, Reno Caps, Flintstones Multivitamins, B Complex 50, Essentiale, Metafolbic Plus, Lipogen, Therems, Daily Vite, Lysiplex, Cernevit, Abidec, Topfit Vitamin B Complex, MVI Adult, Nephronex, Metafolbic, Nephro-Vite Rx, Virt-Vite, 1000 BC, Ivites Rx, Childrens Chewable Multivitamins, Oncovite, Apetigen, Super B-50, Theragenerix, MTX Support, Cardiotek, Topfit Vitamin B Complex Forte, Dialyvite 800, Biotin Forte, Vol-Care Rx, Folplex 2.2, StressTabs, Protegra, Super Plenamins, Essential Balance, Folast, Sunkist Child Chewable with C, Triphro, Geravine, Poly Vit Drops, Mynephron, Surbex, Vitamin B-100, Hexavitamin, One Tab Daily, Vitamin C, E, and Rose Hips, Scotts Emulsion, Mega B, Prostate 2.4, Full Spectrum B with C, Bugs Bunny Multiple Vitamins, Fletanol, Tender Age Vitamin ADC, Vitamin A, D, Vitamin Daily Liquid, L-Methyl-MC, Folbee Plus, Vitamin B Compound Strong, Jetepar, Centrum 8400, Folbalin, Multi Vits with Beta Carotene, Hair, Skin, & Nails Gummies, FaBB, One-A-Day Men's Health Formula, Daily-Vite Men's Formula, Folplex, Vimar, Nature's Bounty Hair Skin & Nails, Foltanx RF, Nufola, Omega Q Plus, Primaplex, Vitaplex, TL Gard, Liponol, Virt-Caps, Neurodep, Poly-Vi-Sol, B-Complex SR, Niva-Fol, Watkins Harvest, Balanced B-100, B-Stress, B-Scorbic, Bee with C, Balanced B-50, Nat-Rul B-125, Balanced B-150, Unicap Capsule, Unicap Jr, Vitacirc-B, Unicap, Optilets-500, Vitamins for Hair, One-A-Day Essentials, Vi-Daylin Chewable, Enfolast, Enfolast-N, Sunkist Child Chewable, Poly-Vi-Sol Chewable, Neurpath-B, Fruity Chew, Poly-Vit Chew, Vita-Respa, Bugs Bunny with Extra C, Flintstones with C Multivitamins, Bounty Bear Vitamins, Garfield Vitamins, Vi-Daylin Drops, Poly-Vi-Sol Drops, Baby Vitamin Drop, Vita Drop, MVC SDV, Glutofac, Allbee-C, Vitabee with C, Stress B with C, High Potency B+C, Av-VITE FB, Farbee with C, Surbex with C, Renatabs, Tri-Vitamin, DEKAs Essential, Vitamin B-50, Folika-T, D-400 international units, Vitamin B-100 T/R, Celebrate B-12, Kenwood Therapeutic, Theravite, Thera-Plus, Glycogenics, Beminal-500, High Potency B Complex with B12 and C, Super B-100 TD, Tri-Vit Drops, Stress Formula, Flintstones Toddler, Stress Formula 600, Tri-Vit, Apatate, T-Vites, L-methylfolate Ca, Me-Cbl NAC, High B Complex, L-methylfolate Ca, P-5-P, Me-Cbl, Beminal, Beminal with C Fortis, Allbee with C, Prevital, Surbex Filmtab, Folgard Rx 2.2, Cernevit-12, SeroSyn, Infuvite Pediatric, Diatx, One-A-Day 50+, Thex Forte, Metafolbic Plus RF, Protegra Cardio, Virt-Vite Plus, Renaphro, Apetex, Virt-Gard, Dialyvite Rx, Folastin, Levomefolate Calcium-Algal Powder, Vesselvite, Folcaps, Combgen, Unichem Multivitamin, L-Methyl-B6-B12, Health Aid Multivitamin, AllanTex, Vitamin A and D Concentrate, One Daily Multi-Essential, Larobec, Cardiotek Rx, Folbalin Plus, Multi-Delyn, Foleve Plus, Foltabs 800, Folnate, Folnate Plus, B-Complex with B-12, Foleve, Folamin, DexFol, Equaline One Daily Essential, Menopause Relief with Lifenol, Av-VITE FB Forte, Folmor, Zycose, Vigomar Forte, Allbee Plus, Triveen-CF, B 100 Complex, Folbic RF, Total B with C, Methaver, GNC Women's Hair, Skin & Nails Formula, Folbee AR, NuFol, Co-Veratrol, Mebolex, Methazel, Mebolic, Dyzbac, Mynephrocaps, Acnepril, Super Theravite-M, Becomject-100, Poly-Vita Drops, MVI-12, B-Ject 100, L-Methyl-MC NAC, Therobec, B-Plex, Formula B, Tri-Vi-Sol, Vi-Daylin ADC, Nephrocaps QT, Lipotriad, Virt-Vite Forte, Stress-600, Cholinoid, Tri-Vita Drops, Thera-Tabs, Bee-Comp with C, Cholidase, Vita-Plus G, Rovin-CF, Cota-B-Plex, Neuroforte-Six, MVI Pediatric, B-Plex Plus, Nephrolan Rx, Zymacap, Vi-Daylin, Dayalets, Sigtab, Allbee-C 800, Cefol, Wellesse Sugar Free Childrens Multivitamin Gummies, Alz-Nac, Sesame St Vitamins with Extra C, Surbex-T, Male Formula, Superplex-T, Vi-Stress, T-BMP, Animal Shape Vitamins, B-50 Complex)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • Pepto-Bismol (bismuth subsalicylate)
  • prednisone (Deltasone, Rayos, Sterapred DS, Sterapred, Prednicot, Meticorten, Liquid Pred, Orasone, Prednicen-M)
  • Prilosec (omeprazole)
  • Synthroid (levothyroxine)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Tramedo, GenRx Tramadol, ConZip, Zydol, Ryzolt, Larapam SR, Tramahexal, Zamadol, Tramal SR, Tramahexal SR, Zydol XL, Rybix ODT, Rybix, Ultram ODT)
  • Tylenol (acetaminophen)
  • Viberzi (eluxadoline)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • warfarin (Coumadin, Jantoven)
  • Xanax (alprazolam)
  • Zantac (ranitidine)
  • Zofran (ondansetron)
  • Zoloft (sertraline)
  • Zyrtec (cetirizine)

Imodium (loperamide) alcohol/food Interactions

There is 1 alcohol/food interaction with Imodium (loperamide)

Imodium (loperamide) disease Interactions

There is 1 disease interaction with Imodium (loperamide):

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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