Comparing Hydroxychloroquine vs Saphnelo

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Hydroxychloroquine	Saphnelo (anifrolumab)	Enter another drug to compare

Hydroxychloroquine

Saphnelo (anifrolumab)

Prescription only

Prescribed for Rheumatoid Arthritis, Lupus, Lyme Disease - Arthritis, Lichen Planopilaris, Dermatomyositis, Malaria Prevention, Malaria, Sjogren's Syndrome, Undifferentiated Connective Tissue... View more

Prescription only

Prescribed for Lupus. Saphnelo may also be used for purposes not listed in this medication guide.

More about Hydroxychloroquine

More about Saphnelo (anifrolumab)

Ratings & Reviews

Hydroxychloroquine has an average rating of 6.4 out of 10 from a total of 356 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 29% reported a negative effect.

Saphnelo has an average rating of 7.9 out of 10 from a total of 11 ratings on Drugs.com. 73% of reviewers reported a positive effect, while 9% reported a negative effect.

View all 356 reviews

View all 11 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Nausea (11.8%)
Rash (9.3%)
Pain (7.9%)
Fatigue (6.7%)
Headaches (6.7%)
Hair loss (5.6%)
Upset stomach (5.1%)

View all Hydroxychloroquine side effects

View all Saphnelo side effects

Drug Class

Selective immunosuppressants

Generic Availability

Lower cost generic

N/A

Pricing and Coupons * Prices are without insurance

Quantity	50 each
Strength	200 mg
Per unit^*	$1.26 - $1.48
Cost^*	$63.03 - $74.19

View all Hydroxychloroquine prices

Quantity	2 mL
Strength	fnia 300 mg/2 mL
Per unit^*	$2,852.06
Cost^*	$5,704.11

View all Saphnelo prices

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Dosage Forms

Oral tablet

Intravenous solution

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

N/A

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category N Not classified

See the full pregnancy warnings document.

Summary unavailable.

See the full pregnancy warnings document.

Drug Interactions

A total of 586 drugs are known to interact with Hydroxychloroquine:

224 major drug interactions (717 brand and generic names)
346 moderate drug interactions (1289 brand and generic names)
16 minor drug interactions (50 brand and generic names)

A total of 228 drugs are known to interact with Saphnelo:

43 major drug interactions (116 brand and generic names)
176 moderate drug interactions (470 brand and generic names)
9 minor drug interactions (37 brand and generic names)

Alcohol/Food/Lifestyle Interactions

You may want to limit your consumption of grapefruit or grapefruit juice during treatment with... View more

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

Infections

First Approval Date

N/A

July 30, 2021

WADA Class View classifications

N/A

More Information

Patient Resources

Hydroxychloroquine uses

Saphnelo uses

Professional Resources

Prescribing information

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Hydroxychloroquine vs Saphnelo

See also:

Humira

Plaquenil

Benlysta

Rocephin

Decadron

Enbrel

Remicade

Amoxil

Dexamethasone Intensol

Imuran

Further information

Comparing Hydroxychloroquine vs Saphnelo

See also:

Further information

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