Comparing Flutamide vs Spironolactone

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Flutamide	Spironolactone	Enter another drug to compare

Flutamide

Spironolactone

Prescription only

Prescribed for Hirsutism, Prostate Cancer. Flutamide may also be used for purposes not listed in this medication guide.

Prescription only

Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more

More about Flutamide

More about Spironolactone

Ratings & Reviews

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Spironolactone has an average rating of 6.9 out of 10 from a total of 703 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 24% reported a negative effect.

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Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

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Acne (11.4%)
Dizziness (8.0%)
Hair loss (7.1%)
Weight gain (5.5%)
Headaches (5.1%)
Tiredness (4.4%)
Fatigue (4.3%)

View all Spironolactone side effects

Drug Class

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	180 capsule
Strength	125 mg
Per unit^*	$0.68
Cost^*	$122.98

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Quantity	100 each
Strength	25 mg
Per unit^*	$0.23 - $0.25
Cost^*	$23.10 - $25.17

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Dosage Forms

Oral capsule

Oral suspension
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

6 hours

37 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category C Risk cannot be ruled out

See the full pregnancy warnings document.

Drug Interactions

A total of 332 drugs are known to interact with Flutamide:

80 major drug interactions (231 brand and generic names)
248 moderate drug interactions (1157 brand and generic names)
4 minor drug interactions (8 brand and generic names)

A total of 382 drugs are known to interact with Spironolactone:

51 major drug interactions (248 brand and generic names)
311 moderate drug interactions (1491 brand and generic names)
20 minor drug interactions (145 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Spironolactone and alcohol may have additive effects in lowering your blood pressure. You may... View more

Disease Interactions

First Approval Date

January 27, 1989

January 21, 1960

WADA Class View classifications

N/A

S5 - Diuretics and Other Masking Agents

More Information

Patient Resources

Flutamide uses

Spironolactone uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Flutamide vs Spironolactone

See also:

Aldactone

Premarin

Trodelvy

Estrace

Eligard

Xtandi

Zytiga

Orgovyx

Lupron Depot

Casodex

Further information

Comparing Flutamide vs Spironolactone

See also:

Further information

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