Comparing Exemestane vs Letrozole
| Exemestane Remove Exemestane from your drug comparison | Letrozole Remove Letrozole from your drug comparison |
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| Exemestane Remove Exemestane from your drug comparison | Letrozole Remove Letrozole from your drug comparison | ||||||||||||||||
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Prescribed for Breast Cancer. exemestane may also be used for purposes not listed in this medication guide. |
Prescribed for Breast Cancer, Breast Cancer - Adjuvant, Breast Cancer - Metastatic. May also be prescribed off label for Female Infertility. |
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Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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See the full exemestane side effects document. |
Commonly reported side effects include: bone fracture, arthralgia, edema, dizziness, fatigue, hypercholesterolemia, osteoporosis, and flushing. See the full letrozole side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all exemestane prices |
View all letrozole prices |
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Generic Availability |
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Yes (this medicine) |
Yes (this medicine) |
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Dosage Form(s) Available |
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Brand Names |
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| Aromasin | Femara | ||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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24 hours |
48 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
Category D
Positive evidence of risk
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
N/A |
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Drug Interactions |
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A total of 73 drugs are known to interact with exemestane:
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A total of 87 drugs are known to interact with letrozole:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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October 21, 1999 |
July 25, 1997 |
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WADA ClassView World Anti-Doping Agency classifications. |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.