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User Reviews for Letrozole

Also known as: Femara

Letrozole has an average rating of 6.4 out of 10 from a total of 300 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 24% reported a negative effect.

Condition Avg. Rating Reviews Compare
Female Infertility  Off-label
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Summary of Letrozole reviews 6.4 300 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Letrozole

Lucky mommy August 31, 2020

For Female Infertility: “I have been trying to get pregnant for about 1 year with no luck. Even tried clomid bad it didn't work. My doctor prescribed letrozole day 2-6. I was lucky I got pregnant the same month. I am now 3 months pregnant. I also tested positive a week prior to my expected periods date. Baby dust to all women looking for a baby. I was here reading people's comments before I took letrozole and I got encouraged. May every woman find encouragement in this.”

9 / 10
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Milie June 29, 2020

For Female Infertility: “I suffer with PCOS, my doctor prescribed me with letrozole after using it I took a pregnancy test 2 weeks later it was positive, I’m now 4 weeks pregnant. I’ve been trying to get pregnant for 6yrs now. I’m super happy, please pray for me”

10 / 10
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Khuli June 15, 2021

For Female Infertility: “Diagnosed with PCOS in Oct 2020 so I heard to go on metformin 850mg for 3 months because I didn't have periods, lucky enough periods came clockwise from Jan 2021. I was then prescribed letrozole 5mg from day 3 to 5, first round nothing, second round I took the same dose again from day 3 to 5 and now am 2 weeks pregnant. Letrozole does work. Please don't lose hope... pray it also works for you.”

10 / 10
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Kay · Taken for less than 1 month May 13, 2021

For Female Infertility: “I was diagnosed with PCOS. I have irregular periods and did not ovulate. Before I was given Letrozole, my OB recommended me to lose weight to increase my chances, I was 5'1 and 207lb. It took me 5 months after dropping the weight from 207 to 174lb. I finally was prescribed Letrozole. I did 2.5mg from cycle day 2 to cycle day 11. Letrozole did help me ovulate on day 15 (peak) and 16 (high). I got pregnant on my first round of Letrozole. Please don't lose hope, thinking of you all.”

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Blessed Mommy · Taken for less than 1 month May 5, 2021

For Female Infertility: “Hubby and I started ttc to July 2020 but I wasn’t ovulating and no periods were present. In October 2020 I was prescribed provera to induce a period and clomid to release an egg. That did not work. I went on birth control for 3 months December 2020 to March 2021 to calm my PCOS ovaries. At the beginning of my last birth control induced period I took one round of letrozole and ovulated on the 14/15 of March 2021 and fell pregnant on my first cycle. I am now currently 9 weeks pregnant. Don’t give up hope!”

10 / 10
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Pandora · Taken for less than 1 month December 11, 2020

For Female Infertility: “PCOS for years After a 6cm ovarian cyst removal surgery, I took 2.5mg Letrozole for days 2-6 of period. I had read online that ovulation can be early, but doc advised it can be at any time, really. Pregnant after 1st cycle of letrozole, I pray for everyone to be as lucky and not give up!”

10 / 10
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RA September 30, 2020

For Female Infertility: “Diagnosed with PCOS since April 2018. Started Femara from July 2020 along with HCG shots. No luck in first cycle. Miracle happened when took same medication for the second cycle. 5 weeks pregnant now. Just 2 cycles of femara and good news is here. Best wishes to all the ladies.”

10 / 10
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Frequently asked questions

Fazz · Taken for less than 1 month January 24, 2020

For Female Infertility: “I took letrozole for one month, two a day for 5 days whilst on my period. I am now 4 months pregnant. I was lucky it worked on me straight away. Took the pregnancy test 1 week prior to my next period and still showed pregnant! It does work, you just have to keep trying and praying for the best! Baby dust to everyone trying x”

10 / 10
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Ubaid khan · Taken for less than 1 month July 13, 2021

For Female Infertility: “I have PCOS since 2018 and even hypothyroidism, I knew I was not ovulating so I went to my gynecologist and discussed my history. She gave me letroz 2.5 tablet from 3rd day of cycle to 7th day and I went for follicle scanning. Doctor said everything is fine but unfortunately there was no pregnancy. Now I'm on my 2nd round of letroz with same dose. I am hoping for the best, I pray for every lady who is trying to get pregnant they wish get fullfilled..!!”

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Raj · Taken for less than 1 month December 3, 2020

For Female Infertility: “I tried letrozole first time and I conceived, I'm now 4 month pregnant - it’s magical for me”

10 / 10
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Aimsley · Taken for less than 1 month February 6, 2021

For Female Infertility: “I was unable to ovulate on my own due to hormonal imbalance/PCOS. After trying to conceive for almost 20 years and doctors not fully addressing my infertility issues I found a doctor that prescribed me Letrozole. I successful ovulated from left ovary on cycle day 17 and then had second successful ovulation from right ovary on cycle day 19. Both were confirmed from a Trans vaginal ultrasound. Here I am several days late but waiting 3 more days until testing for most accurate results. Baby dust to everyone trying! Dosage was 2.5mg starting on cycle day 3. Taken for 5 days.”

10 / 10
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Anonymous · Taken for 1 to 6 months November 7, 2020

For Female Infertility: “Has anyone used letrozole for 6 months, ovulated but not conceived?”

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Unknown · Taken for less than 1 month September 21, 2021

For Female Infertility: “I write this to encourage someone! Reading about your experiences encouraged me too. I was diagnosed with PCOS in August 2021. My periods are so irregular therefore I was put on Medroxyprogesterone/Provera 10mg for 7 days to induce a period. My period started 2 days after stopping it. My Dr prescribed Letrozole 5mg day 2-6 of my cycle. I had a scan on day 13 and I had 2 dominant follicles. On day 14 my Dr gave me an Ovidrel shot to trigger Ovulation. Now I’m 3 weeks pregnant. This was my first cycle of Letrozole. I pray for everyone reading this. Jesus did it for me! He will do it for you too. Remain positive and expect the best.”

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Cindy D · Taken for less than 1 month January 6, 2021

For Female Infertility: “I have been suffering from PCOS for a year now. Took Femara 2.5g from day 3-7 of my cycle for 1 month. Well ... I’m gonna be a mom. Hope this helps someone like it helped me”

10 / 10
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Anonymous · Taken for 1 to 6 months July 29, 2020

For Female Infertility: “I had been trying to get pregnant for 2 years. Did a few rounds of Clomid without results. Got diagnosed with PCOS. Did one round of Letrozole 5 mg and trigger shot without results. For round two my doc upped it to 7.5 mg plus trigger shot and it was successful! Daughter is now 1 year old and we are trying again starting at 7.5 mg. Experiencing depression, fatigue, and intense dreams. Baby dust to all!!”

7 / 10
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Nicky · Taken for 1 to 6 months January 18, 2021

For Female Infertility: “I used Femara (letrozole) 2.5mg for cycle day 3-7 for the first month, then the second month 5mg cycle day 3-7, but nothing. Until 3rd month, same dose 5mg cycle day 3-7 I got my first positive! Fingers crossed everything will be okay! Praying for all of you! I was going to stop at the second month, because I did had bad side effects but something told me to keep going!”

10 / 10
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Ishii · Taken for 1 to 6 months May 7, 2020

For Female Infertility: “Hi there, My fertility doctor prescribed me letrozole 2.5 mg for 3 months. So far I have just completed my first cycle. My periods got delayed by 3 days. I was about to the pregnancy test and saw spotting. Its sad but I am not going to loose hopes. Will try again . Wish me luck ”

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More FAQ

Sj · Taken for less than 1 month March 2, 2021

For Female Infertility: “I was diagnosed with PCOS 3 months ago after going to a fertility clinic, although I thought I had it when I was admitted to hospital 4 years ago with a cyst, that popped and made me really sick! The doctors just shrugged it off and this happened twice ! I’ve just started take letrozole 5mg day 2-6 and just received my smiley face !! Side effects was bad headaches that I couldn’t shake off and hot sweats, later on before I ovulated I felt like my ovaries were going to pop (google this thinking it was going to happen ) so fingers crossed my next cycle will be the one and We will get our first BFP !!! For those TTC I send lots of baby dust your way, and those that are already there I wish you a happy wonderful pregnancy x”

10 / 10
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JP · Taken for less than 1 month September 9, 2020

For Female Infertility: “I have PCOS and have struggled with my irregular periods all my life. In 2017 I TTC and used Letrozole for one cycle... 2 pills a day for 5 days and BOOM! Preggo! After trying for 5 years it was a miracle pill! Now I want baby number 2... to my surprise 3 years older and same medication has the opposite effect. February 2020 did Round one, one pill for 5 days. No luck. Then Covid hit! Smh. Started again in Aug 2020 round 2, 2 pills for 5 days. I figured this was the same dosage as baby#1 so it would definitely work and nothing. My heart was broken.. no luck again!? Currently doing round 3. Doctor increased the pills to 3 a day for 5 days.. Getting checked next week and hopefully the trigger shot will help. I can say it works from past experience but I honestly believe age and dosage has a lot to do with it. Wish me luck! And wishing you all The best.. keep your heads up.. it can still happen! -jp”

10 / 10
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Anonymous · Taken for 1 to 6 months November 21, 2021

For Female Infertility: “everything was normal, regular period proper ovulation still failed to get pregnant we tried for 6 months. I took letrozolr 2.5 mg twice a day from day 3 to 7 and in the same month I got pregnant in fact after 7 weeks I found it is twins and now I am 3 months pregnant. So this medicine works. In my case may be it induced more than one egg. Whatever, but this medicine works for natural conception.”

10 / 10
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Rubia V. February 1, 2021

For Female Infertility: “I am 17 weeks along with my first baby after 5 cycles of letrozole. I was trying to conceive for years, of course it's a group of things that need to be changed in your mind: Think positively , everyone was getting pregnant before me and I was putting myself down. We all have our own time to shine, be happy for everyone else. Have a diary on an app so u can log in your symptoms, days you had sex, etc... I lost a ton of weight before I got pregnant, so eat better, cut down on alcohol. And all of that helped to conceive Good luck ladies. You will get there also x”

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Des · Taken for less than 1 month January 18, 2021

Femara (letrozole) for Female Infertility: “Had my 1st round of Femara in December. I did ovulate for the 1st time that I’m aware of in a long time due to PCOS. I did end up pregnant, but sadly had a chemical pregnancy around 3 weeks. I’m thankful that it did work for us and I was able to conceive. Now is the hard part of figuring out where to go from here. Prayers and love to all!”

10 / 10
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N May 12, 2020

For Female Infertility: “I was trying to get pregnant from 10 months I went to infertility specialist although I didn't have pcos but I took letrozole for three months and got pregnant on the third cycle....blessed with a baby .... I don't understand if I didn't have pcos how did it work ? Another point to note is I was given link tablet local brand and since I couldn't find that brand I took glaxsomsith letrozole on third cycle and got pregnant.”

9 / 10
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Rajvi · Taken for 1 to 6 months August 6, 2020

For Female Infertility: “I have PCOS for one year.It’s my second cycle with letrozole and I got positive test today.. thanks to letrezol.. just be patient.. it works for sure.”

10 / 10
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Duchess · Taken for 1 to 6 months January 29, 2019

For Breast Cancer: “I was diagnosed with stage 1 breast cancer in 2015 at age 58. A lumpectomy was performed and I was treated with four weeks of radiation. The cancer was 98% estrogen positive. I began first with Arimidex post op but after a while I experienced severe muscle cramps (which may have been caused by a combination of medication problems at the time) and eventually switched to Letrozole. The cramping that I experience in my legs now is not nearly as severe and is doable. I've been on the Letrozole about a year and a half now. I'm writing because I wanted to let you know that if you are experiencing hair thinning while on Letrozole, I have found that taking a B-complex vitamin pill on a daily basis has been very helpful for me. My hair was thinning, but after about six months of taking a B-complex vitamin pill everyday I noticed that my hair thickened and that it now basically stays in my head. Just wanted to pass this information along.”

7 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.