User Reviews for Letrozole to treat Breast Cancer, Metastatic
Also known as: Femara
Letrozole has an average rating of 6.8 out of 10 from a total of 22 ratings for the treatment of Breast Cancer, Metastatic. 59% of those users who reviewed Letrozole reported a positive effect, while 27% reported a negative effect.
“Been on this drug for 3 months. Extreme hot flashes the. Severe chills. I am sleepy all day. I go to bed sleepy. I wake up sleepy. I fall asleep anywhere. My quality of life is gone because of no energy. Hair loss. Weight gain. Depression which I did not have before. Dizziness and mental fogginess. All of these symptoms Every.Single.Damn.Day”
“It caused horrid pain throughout my entire body and skin 3 weeks into the drug. Also major mood changes - mostly depression and grumpiness. Not the quality of life I am looking for.”
“I was diagnosed with Metastatic breast cancer 2-9-2016. I am ER and PR Positive Her2 Negative, I am still on my first line of treatment (Letrozole 2.5 daily.(Bone Metastasis only!) Zometa infusions every three months Letrozole has been a wonderful drug for me. Very Minimal side effects. I am currently in month 43 of Letrozole (Femara). I am very thankful for the makers of this drug...”
Frequently asked questions
- How does Femara affect your period?
- Does Femara make your hair fall out?
- When do you ovulate on Femara?
- Can Femara cause twins?
- What is the success rate for Femara in breast cancer?
Femara (letrozole): “I've been taking Femara since the breast cancer was discovered in my lung - that has been 10 years this year. Two types of chemo failed to knock it out and as I was preparing for radiation, I started taking Femara. Within a month the tumor began to shrink and all that is left is scarring where it once was. I am so grateful to my doctor for recommending it to me. My other oncologist didn't even mention it. Needless to say I'm happy to be alive and enjoying life.”
Femara (letrozole): “I have been using Femara for 8 months, and I have been having very few side effects. I get the hot flashes only once in a while now. I do have some joint pain, but that has been easy to tolerate, if that means I will have a longer life, but only GOD knows that. There is always hope, just keep the faith and have no doubt in the medicine, doctors and mostly GOD.”
Femara (letrozole): “Femara for 18 months no side effects for first 6 months, then joint and muscle pain, physical fatigue, bone density loss. Will continue for as long as it works, at the moment looking clear, I want to live.”
Femara (letrozole): “After 7 years of several different medicines to try to stop the growth of the tumors, Femara is the only one which worked for me. My WBC is higher, the tumor has actually shrunk in the breast - but being realistic, it's not a cure-all, a patch for a longer life but eventually we all expire. I highly recommend this product for those who want longevity without losing your quality of life.”
- Aromasin vs Femara - how do they compare?
- Which is better - Aromasin or Femara?
- What is Femara (letrozole) and what is it used for?
Femara (letrozole): “Breast Cancer in 1999 Stage 1 Distant recurrence lung tumor in 2012. Given Femara (letrozole). After two months tumor shrunk. Almost 3 years now on letrozole. No side effects and no evidence of disease.”
Femara (letrozole): “After a year on Femara I am beginning to experience severe hair loss, bald patches on top of my head and the hair is turning thin and brittle. Insomnia for the last 2 months, pain in my joints, I was diagnosed with Glaucoma and am very forgetful, i.e. find it defficult to concentrate. But, if Femara stops the recurrence of cancer, I'll keep taking it. If it just were not for the hair loss. ”
“2018 the worst year of my life Got suddenly diagnosed with met left breast cancer so shocked underwent mastectomy, radiation. HER negative Hormone positive, Underwent oophorectomy to decrease estrogen levels Now on letrozole since 14 months Horrible, hot flashes and night sweat severe arthritis Still coping Thinking of stopping letrazole But oncologist said to continue and have patience Let us hope for better future”
“At 75 I was paralyzed from the waist down and diagnosed with stage 4 ovarian cancer & paraneoplastic syndrome. My main tumor was size of an American football, with Mets. Given 1 dose of chemo. 2 weeks later I got pneumonia, a UTI and severe sepsis. My kids were told I had 2 hours to live. Still there the next day I was given a 1% chance of living for a month. More chemo was out so was put on Letrozole. After 8 months of paralysis, I moved my right foot. I started physio, and within 3 months I learned to stand then walk. A year on, my tumors continue to shrink. Then joint pain started after about 8 months in hips, wrists, knees, ankles & bones on top of my feet and I seized up every time I take a break and have start all over again. Morning is hardest. But the bottom line is I am alive. I have been declared a medical miracle... and I owe it all to Letrozole. The pain can be quite bad at times but I take no pain killers. I just sit down and consider the alternative! Thank you Letrozole”
“I had breast cancer 9 yrs ago, stage 1. I had 4 mo’s chemo, 6 weeks radiation. Then a 1 1/2 yr. ago it came back, stage 4, and it metastasized to both my lungs. Now, I’ve been on Letrozole 1 1/2 yrs and a few of my tumors shrunk and have stabilized the others. I’ve have some side effects, which is brain fog, night sweats, fatigue and dryness. It’s been very tolerable. I call Letrozole my miracle pill! Good luck to you all! ❤️”
“Hi, I'm a new member, I had breast cancer at the start of 2013, it had spread to my liver, bone and spine, I had radiotherapy on my spine which worked well, I was then put on letrozole, within 6 months, the scan results showed that all the tumors were shrinking, I had awful hot flushes but coped with them, in April 2014 my scan was clear and was pain free and this was just by taking letrozole, I called it my wonder pill. However, the last few weeks the muscle pain in my legs have started, I went to the health shop and got some Musseltone gel, yes I have spelt it right as it's made from mussels from the sea, it's great, I rub it on a few times a day and before I get out of bed in a morning. For me, Letrozole was my miracle cure.”
“After a modified radical mastectomy for stage 3 breast cancer, I took letrozole for 5 years and my tumor marker test (CA 15-3) remained low. My oncologist and I decided that without any indication of malignancy I could safely go off the letrozole. After 2 years off it my (CA 15-3) blood test shot up and I was diagnosed with metastatic breast cancer on my chest wall. I resumed taking letrozole and had 36 radiation treatments. I have taken letrozole for 7 months now and my most current CT scan showed the lesion was gone. I know the radiation destroyed most of the lesion but I'm sure the letrozole helped a lot with the rest. I probably will take letrozole for the rest of my life.”
“I’m 54 yrears old & I’ve been taking this Rx, for my MBC w/Extensive Bone Mets, for 6 months. Last week, I suffered a spontaneous fracture of the tibia & fibula bones in my ankle! Might need surgery in a few weeks. I called the manufacturer & they confirmed it can cause osteoporosis & fractures in 14% of patients (in clinical trial #1 & 9% in a second clinical trial.) Also, my vision is getting a bit worse & they confirmed it can also cause several vision problems, in less than 4% of Letrozole users. I’m never, ever taking this drug again!”
“I had ER+ HER- stage III 23 positive lymph nodes. Diagnosed Christmas before last. Age 47. Neoadjuvant ACT,surgery,radiation. Letrazole was the first aromatase inhibitor I tried.I am so sorry to hear of the side effects many have had. I have had a few. Gained a little weight,constipation. But I had serious joint pain and stiffness before I had cancer. The chemo made my joint pain and stiffness go away. Even my hips.When I finished it crept back. Then I started letrazole and it went away. I know this helps me becuase I ran out of it on vacation for two days and could barely move the day I got my refill. After three doses I was back to normal. That is good because I have to take it as long as I live.”
“It was toxic to me. Severe joint pain, insomnia, osteoporosis, increased cholesterol count, and spinal stenosis. I also lacked libido and energy. It is worth the small chance of reoccurrence. I am still in pain, and I have been off of it since the end of April. It has impacted my life enormously; I regret taking it.”
Femara (letrozole): “I'll make this as brief as possible: This drug isn't putting a dent on ceasing tumor progression in me. Unfortunately, the intravenous chemo [Abraxane] I was on had plateaued and was no longer effective. I have no idea what I will be going on next.”
“Started letrozole as second line treatment, after tamoxifen (2.5years), for Mets in bones, lymphs and primary still present. Breast tumours just continued to grow, the smaller one more than doubled in 6 weeks. Side effects depended on the brand, was unable to function on one, but once changed it was manageable, just some terrible hot flushes/sweats in the evening. Had hoped to get at least a year on this treatment, but now threatened with radiotherapy to spine and chemo.”
“I am taking Letrozole (Femara) and I have malignant pleural effusion secondary to breast cancer. I had my first lympectomy with lymph node removal in 1996 with radiation. Second lymphectomy in 2003 with no treatment. Mastectomy (all the same breast) in 2013 with chemo. Now, I have been diagnosed with malignant pleural effusion (MPE) and have been put on Letrozole. The side effects are really bad from the hot flashes to severe bone and joint pain. Has anyone out there been in my situation and can give me more insight about whether to take or discontinue the letrozole. Thanks in advance.”
“Update from 2015. Still on Letrozole, still no side effects, and still no sign of cancer. It has been 6 years now. It has been the first and only treatment I have had with metastatic breast cancer.”
Femara (letrozole): “Had to get off of this. I still work and could not get past the "brain fog" and severe joint pain.”
“Switched to Letrozole and Ibrance from Xgeva and Denosobaum April 2015 The weight gain, hair loss and depression are an impending deal breaker. Sorry. Cant live like this.”
This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.
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