Letrozole Alternatives Compared
| Letrozole | Metformin | Clomid |
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| Letrozole | Metformin | Clomid (clomiphene) |
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Prescription only
Letrozole is a treatment that may be used to reduce the risk of breast cancer recurrence in postmenopausal women and also to increase the chance of ovulation in women with polycystic ovary syndrome... View more |
Prescription only
Metformin improves how the body responds to insulin and it is effective for the treatment of type 2 diabetes. Taste disturbances, diarrhea, and other stomach-related side effects are common side... View more |
Prescription only
Prescribed for Oligospermia, Ovulation Induction, Female Infertility, Lactation Suppression. Clomid may also be used for purposes not listed in this medication guide. |
Related suggestions Female Infertility
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| More about Letrozole | More about Metformin | More about Clomid (clomiphene) | ||||||||||||||||||||||||
| Generic Status | ||||||||||||||||||||||||||
| Ratings & Reviews | ||||||||||||||||||||||||||
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Letrozole has an average rating of 6.4 out of 10 from a total of 337 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 24% reported a negative effect. |
Metformin has an average rating of 6.9 out of 10 from a total of 632 ratings on Drugs.com. 56% of reviewers reported a positive effect, while 19% reported a negative effect. |
Clomid has an average rating of 8.0 out of 10 from a total of 214 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 13% reported a negative effect. |
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| Drug Class | ||||||||||||||||||||||||||
| Side Effects | ||||||||||||||||||||||||||
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Commonly reported side effects include:
See also: letrozole side effects in more detail. |
Commonly reported side effects include:
See also: metformin side effects in more detail. |
See also: Clomid side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | ||||||||||||||||||||||||||
View all letrozole prices |
View all metformin prices |
View all Clomid prices and generic prices |
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| Dosage Form(s) Available | ||||||||||||||||||||||||||
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| Brand Names | ||||||||||||||||||||||||||
| Femara | Glumetza, Riomet, Riomet ER |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | ||||||||||||||||||||||||||
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48 hours |
4.5 hours |
120 hours |
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| CSA Schedule ** View glossary of terms | ||||||||||||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||||||||||||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||||||||||||||||||||||||||
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A total of 103 drugs are known to interact with letrozole:
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A total of 358 drugs are known to interact with metformin:
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A total of 4 drugs are known to interact with Clomid:
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| Alcohol/Food/Lifestyle Interactions | ||||||||||||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||||||||||||||||||||||||||
| First Approval Date | ||||||||||||||||||||||||||
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June 03, 2011 |
January 18, 2012 |
N/A |
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| WADA Class View World Anti-Doping Agency classifications. | ||||||||||||||||||||||||||
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N/A |
N/A |
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| Patient resources | ||||||||||||||||||||||||||
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N/A |
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| Professional Resources | ||||||||||||||||||||||||||
| Related Treatment Guide | ||||||||||||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.