Letrozole Interactions
There are 121 drugs known to interact with letrozole, along with 3 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 17 are major, 96 are moderate, and 8 are minor.
- View all 121 medications that may interact with letrozole
- View letrozole alcohol/food interactions (1)
- View letrozole disease interactions (3)
Most frequently checked interactions
View interaction reports for letrozole and the medicines listed below.
- Aspirin Low Strength (aspirin)
- Aspirin Low Strength (aspirin)
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- Claritin (loratadine)
- CoQ10 (ubiquinone)
- CoQ10 (ubiquinone)
- Eliquis (apixaban)
- Eliquis (apixaban)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Fish Oil (omega-3 polyunsaturated fatty acids)
- Ibrance (palbociclib)
- Ibrance (palbociclib)
- Lexapro (escitalopram)
- Lexapro (escitalopram)
- Metoprolol Succinate ER (metoprolol)
- Metoprolol Succinate ER (metoprolol)
- Synthroid (levothyroxine)
- Synthroid (levothyroxine)
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Zyrtec (cetirizine)
- Zyrtec (cetirizine)
Letrozole alcohol/food interactions
There is 1 alcohol/food interaction with letrozole.
Letrozole disease interactions
There are 3 disease interactions with letrozole which include:
Report options
More about letrozole
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- Drug class: aromatase inhibitors
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Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
