Letrozole User Reviews & Ratings (Page 4)

• Anonymous
• May 23, 2010

Letrozole for Breast Cancer "I was on Tamoxifen for 2 years following breast cancer and doing fine. My oncologist wanted to try Femara because it could be a little better. I was on it for about 3 months when I awoke in the middle of the night with horrible joint pain. It had been coming on slowly, but I thought it was carpal tunnel, maybe arthritis. Then I realized that my doctor had said that joint pain was a possible side effect of Femara. I was also gaining approximately 2 pounds a month! I have been off of it for a month now, but am still having pain. It is worse in the mornings and evenings. Trying to grip with my hands is very difficult some mornings. My doctor said it could take a few months to get this out of my system."

• Pos...
• Taken for 1 to 6 months
• January 28, 2014

For Breast Cancer "I have been on letrozole for 5 months. I experience pretty strong joint pain in hands, fingers, and feet, especially upon rising in the morning. I look like Walter Brennan going to the bathroom. I am 54 and previously felt like 25, now I often feel 85. I have found something great to prevent weight gain and help with the energy issue. Still working on vaginal dryness and libido. Have found an anti-inflammatory diet improves pain, energy, and mental clarity."

• Abc...
• October 25, 2020

For Female Infertility "I have taken letrozole 2.5 mg from day 2 to day 6 in Aug 2020, but I got my periods. Then my doc recommended me clomid 50 mg next month, but I didn't take it as my flow was very light. Now my doc again recommended me letrozole 2.5 mg, so hoping for a positive test next month. Wish me luck, and please pray for me... may everyone get a baby soon."

• Fat...
• Taken for less than 1 month
• March 27, 2023

Letrozole for Female Infertility "If you came here to look at reviews, that means you are planning to conceive, and baby dust to all hoping for pregnancy, including me. I found out last year that I have PCOD and that my thyroid (hypothyroidism) is extremely high; it was 11 and is now around 4, so I need to reduce it even more for conception. My gynecologist advised me to take Clomid for two cycles without success, and this month she advised me to take Femara (letrozole) from the second day of my period to the fifth day. I really hope it works. I read a lot of your reviews and got a positive feeling! Insha Allah, I get my positive news soon, and I hope the same for every other woman who is looking forward to pregnancy! We've got to be strong and positive! Lots of love to all."

• Clp...
• Taken for 6 months to 1 year
• January 16, 2021

For Female Infertility "My story: I did not have any periods for a year and, after tests, was diagnosed with PCOS. I was referred to a fertility clinic as I had been trying to conceive for over a year. They started me on 2.5 mg letrozole to kickstart ovulation, but I didn’t ovulate in the first month, so the dose was doubled to 5 mg (two tablets), and I began to ovulate, which was good news. However, unfortunately, after 6 months of taking double letrozole, I have not had a pregnancy. I’m now being referred for IUI/IVF. Everyone is different, and it’s nice to see the success stories here. Many ladies seem to have achieved pregnancy with letrozole, which is lovely, it gives us hope. Stay strong and keep going."

• Liz...
• Taken for 2 to 5 years
• February 2, 2021

For Female Infertility "I hope you all get pregnant, but this is a drug review site. That being said, here is my review. I have PCOS and conceived on the first round of letrozole in December 2019. I miscarried in January. I conceived again on the second round in July 2020 and miscarried in September. I am currently on my next round: 5 mg, days 3-7, and the side effects are tiredness, dizziness, blurred vision, depression, and anxiety. It’s only 5 days, ladies. It’s worth it. It works. Hang in there."

• Jil...
• November 30, 2015

Letrozole for Breast Cancer "Stage 4 HER2-positive breast cancer was found in 2011. After a double mastectomy (additionally, 6 other surgeries due to Staph infection and failed reconstruction attempts), 6 months of 2 types of chemotherapy, including Neulasta booster shots after each infusion, a total of 1 year of Herceptin chemo infusions, 6 weeks of daily radiation, then 8 years of Femara. Been taking this medication daily since August 2012. Hot flashes and night sweats are awful. Anxiety occasionally. Easily out of breath after any activity. Difficulty maintaining focus and frequent forgetfulness. 3 years with this medication and chest, bone, and joint pain is intensifying. 5 more years to go. CANCER FREE STILL."

• SG2...
• Taken for less than 1 month
• December 4, 2021

For Female Infertility "I wanted to share this to give people hope, as I was the one sitting here reading all comments recently. I have PCOS and was put on Letrozole as I was trying to conceive since July, only had 2 cycles and wasn’t ovulating. Went to a gynecologist who put me on 2.5 mg on cycle day 5-9 and he advised that generally a lot of women ovulate around day 17. This was my first cycle on the medication, I was getting symptoms on cycle day 17/18 and decided to try an ovulation test on day 18 (always had negatives with ovulation tests as I know these aren’t reliable with PCOS) and for the first time ever, it came back with a positive smiley face, so we made sure to try then. I was getting some early pregnancy symptoms around cycle day 24 but could also be mistaken for PMS, so didn’t want to overthink it. I took a pregnancy test yesterday, dpo 12/13 and got my first BFP!! I have a doctor's appointment in a few days to confirm, so fingers crossed everything goes ok."

• mar...
• May 21, 2013

Letrozole for Breast Cancer, Adjuvant "When I switched aromatase inhibitors from Arimidex to Femara, it was a world of difference! The terrible side effects I was experiencing made me question whether survival from breast cancer was worth it, if my life would be spent with Arimidex side effects of irritability, more hair loss, joint pains, etc. My oncologist switched me to Femara, and my life returned to be more pleasant and energetic. I have been suggesting this change to all my blogging support group members who are having problems with Arimadex. Later, adding OTC Biosil and SamE have also helped with the hair, joint, and mood issues."

• Ana...
• Taken for less than 1 month
• August 28, 2020

For Female Infertility "I have PCOS. I have taken Clomid for 3 months to try and get pregnant, but it didn't work. Now my doctor gave me letrozole 2.5 mg. However, after my last day of my period, I am still having vaginal bleeding. Is that normal?"

• Sti...
• May 23, 2010

Letrozole for Breast Cancer, Metastatic "After 7 years of several different medicines to try to stop the growth of the tumors, Femara is the only one which worked for me. My WBC is higher, the tumor has actually shrunk in the breast - but being realistic, it's not a cure-all, a patch for a longer life but eventually we all expire. I highly recommend this product for those who want longevity without losing your quality of life."

• Anonymous
• November 18, 2011

Letrozole for Breast Cancer, Adjuvant "After reading of so many negative side effects of Femara, I was hesitant to start. Since it decreases my chances of recurrence by 25%, I felt I must try it. I've been on it for 1 year now and have had very few, if any, negative side effects. My hair regrowth has been spotty and slow, whether due to the Femara or just the general effects of chemo and radiation, I'm not sure. I switched 2 months ago to the generic formula, have noticed no changes. I feel very fortunate not to have suffered many of the effects other women have reported."

• CHA...
• Taken for 6 months to 1 year
• February 26, 2014

For Breast Cancer "Was on Arimidex for one year but was changed to Letrozole because I couldn't walk due to burning sensation. Side effects after treatment have been: bone weakening, fatigue, insomnia, night sweats, weight gain (40 lb), dry hair, feel older than 71, redness in my face, high blood pressure, neuropathy, burping, stiffness after sitting, memory loss, joint pain...but I am happy to be alive. I try not to complain because I want my husband to be happy."

• Sco...
• Taken for 1 to 2 years
• February 25, 2020

For Breast Cancer "In January 2019, I was diagnosed with breast cancer, Stage 2. 58 years old. Left breast mastectomy with no radiation and no cancer in the lymph nodes. Given Letrozole 2.5 mg. Side effects of this medication: severe hot flashes, chills, severe pain in my hands, knees, feet, and legs, foggy head, muscle pain, insomnia, poor memory, extreme tiredness, canker sores, and occasional pain in my upper abdomen. During the first four months, I experienced hair loss and itchy hands. I quit my job as I was just too tired to continue. Now, I wish I would have quit Letrozole instead. I will see my cancer doctor in a few months, and this will be discussed. If I don’t quit before."

• Lod...
• Taken for 1 to 6 months
• July 1, 2022

For Female Infertility "Since I know myself, I had irregular periods due to PCOS. My BMI is in the normal range, and I do not have diabetes. Several years ago, I had an ovary torsion surgery due to a large water cyst. Luckily, both of my ovaries were saved, but I was always concerned about my fertility. When I decided to get pregnant (age 33), I went to the doctor right away. They gave me letrozole 2.5 ml starting from day 3. Unfortunately, I did not ovulate the first time. I was very upset and worried, thinking I might have a problem. They increased the dosage to 5 mg. No side effects again, but this time I had a dominant follicle of 17 mm CD11 and 20 mm CD13. It was on my right ovary, where I had the surgery. I was quite skeptical whether it was going to work or not... It did! I am now 6 weeks pregnant! I hope all goes well. Letrozole works, don't lose hope. Thinking of all of you!"

• mar...
• Taken for 2 to 5 years
• February 17, 2015

Letrozole for Breast Cancer, Metastatic "Breast Cancer in 1999. Stage 1 distant recurrence lung tumor in 2012. Given Femara (letrozole). After two months, tumor shrunk. Almost 3 years now on letrozole. No side effects and no evidence of disease."

• Jen...
• August 8, 2019

For Breast Cancer "A mammogram found a lump in my breast and I had a lumpectomy, followed by 5 weeks of radiation and the hormone blocker letrozole, which my oncologist strongly recommended. For about 3 years prior to the surgery, I had problems with back pain, lack of energy, depression, and asthma, which caused me to be very short-winded. Since the radiation, I find I'm more tired and my breathing is worse. I wake up tired, I go to bed tired. The letrozole has caused sweats and hot flashes worse than ever before. I wake up with excruciating joint pain every day, so bad that it feels as though my wrists, fingers, or arms are broken. During the night, my hips ache so much that I have to turn on my back. It is also causing hair loss. I'm on oxycodone, so once I get up and take the painkillers, the joint pain goes away. I was going to switch to tamoxifen until I read the side effects and the patient ratings, which were much worse than letrozole."

• Lai...
• Taken for 10 years or more
• May 26, 2019

For Breast Cancer, Adjuvant "Diagnosed 22 years ago with invasive lobular breast cancer, and 45 out of 48 lymph nodes contained cancer. (Really.) But after mastectomy, chemo, radiation, more chemo, 5 years of tamoxifen, a complete hysterectomy, a couple of years of anastrozole and exemestane... I've been on letrozole for well over 10 years. I have experienced most of the usual side effects, but I've lived to complain about them. :-) No recurrence so far, although I did develop another breast cancer and had a second mastectomy 10 years ago. Overall, I eat healthy and work out, I do have energy, not much pain anymore, and I still work FT at age 66. Clearly, I've been lucky. No one expected me to live (least of all me). But statistics do not determine what will happen to the individual. Life is good!"

• Anonymous
• December 13, 2009

Letrozole for Breast Cancer "I am 52 years old, and I too feel older than I am. I already have problems getting out of bed, and I suffered with sarcoidosis, which affects the organs and causes joint pain, sending me constantly to different specialists. Now I am taking Femara, and it's not only causing me more pain, but it's causing my hair to fall out or thinning! I also notice that my vision is impaired sometimes when I'm driving, and I only drive when I have to, but sometimes I find myself trying hard to focus. This is scary! I am calling my oncologist tomorrow morning first thing."

• Anonymous
• September 24, 2020

For Female Infertility "I took Clomid, and it was unsuccessful with ovulation. The doctor then advised me to take letrozole 5 mg. I took that in cycle 1 and started my periods on day 35. I have now taken it for my second cycle, however, I am due to start my periods in 3 days. Wish me luck."

• Shr...
• Taken for 1 to 6 months
• March 23, 2020

For Female Infertility "I used letrozole 2.5 × 2 in 1 month and also take Lupin 75 injection. I expected this month to conceive, but with my bad luck I didn't. I don't know what to do. We've been trying to get pregnant for 2 years, but no positive result. I have PCOS problem. Wish me luck, friend."

• fae...
• October 1, 2016

For Breast Cancer "I'm 61 years of age. Approaching my 4th year of taking letrozole Accord. I am suffering with joint ache which attacks my knees, one ankle. Wrists, elbows but has now affected my hands, most particularly my middle fingers of each hand! I also get pins and needles in my hands. The morning stiffness is throughout my joints and takes a while to get going. I have calf pain and muscle weakness and blurry eyesight too sometimes. I don't complain as it's prevented the cancer returning. I do despair at my poor quality of life. I take calcium, magnesium, and pain relief. I walk every day and exercise. I've also gained weight. I'm glad to know there are others with similar side effects but even more glad that I'm here to share my story."

• Anonymous
• Taken for less than 1 month
• March 20, 2020

For Female Infertility "I have been seeking to get pregnant for years. I have already started IVF and have an embryo. I am getting ready for a transfer. My doctor prescribed a couple of medications, one was letrozole. This drug got me pregnant, and I wasn't even paying attention to intercourse due to already having an embryo. I had sex when I felt like it. Boom! I got pregnant. Unfortunately, my HCG levels started dropping."

• min...
• September 12, 2015

Letrozole for Breast Cancer "In 2011, I was diagnosed with stage 3A invasive ductal breast cancer. I went through chemo for 4 months and had a double mastectomy in March 2012, followed by 6 weeks of radiation. I was put on tamoxifen for a year and then Femara, which I currently take now. The biggest thing with Femara is feeling constantly tired and 'foggy'. I can handle the hot flashes (we live in Minnesota, where the winter lasts for 6 months) - I just walk around outside with a t-shirt on, and I'm good to go! Lately, I have been experiencing hair loss, and I don't know if it's due to the Femara. Anyone else have this problem? Please let me know. Hang in there, beautiful ladies (& men)."

• apr...
• March 21, 2016

Letrozole for Breast Cancer "I have been on this drug for about 3.5 months now. I was on Aromasin (exemestane) for 2.5 years prior to starting letrozole. I was so hopeful that some of the horrible side effects would not affect me like they did on the exemestane...and for a while, it was not too bad. Now, in month 3, the side effects of severe joint pain, brain fog, and shortness of breath are back with a vengeance, and the last 3 times my blood pressure was taken, it was inching back up even though I started BP meds after the exemestane raised my BP. I never had any issues with my BP prior to taking these aromatase inhibitors. I guess my PCP will have to raise my dose of BP meds. I am also peeing constantly on letrozole, and my hair is coming out more on my brush! UGH!"