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Letrozole User Reviews & Ratings (Page 2)

Brand names: Femara

Letrozole has an average rating of 6.5 out of 10 from a total of 367 reviews on Drugs.com. 48% of reviewers reported a positive experience, while 21% reported a negative experience.

Reviews for Letrozole

Commonly mentioned side effects
  • Ash...
  • Taken for less than 1 month
  • September 25, 2019

For Female Infertility "Doctor started me on Clomid to help me get pregnant. Did that for 2 months. Then doctor said I didn’t ovulate the last month, so she then started me on letrozole. Took those days 3-7, and now I’m 9 weeks along."

10 / 10
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  • Rub...
  • February 1, 2021

For Female Infertility "I am 17 weeks along with my first baby after 5 cycles of letrozole. I was trying to conceive for years. Of course, it's a group of things that need to be changed in your mind: Think positively. Everyone was getting pregnant before me, and I was putting myself down. We all have our own time to shine, be happy for everyone else. Have a diary on an app so you can log your symptoms, days you had sex, etc. I lost a ton of weight before I got pregnant, so eat better, cut down on alcohol. And all of that helped to conceive. Good luck, ladies. You will get there also. x"

10 / 10
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  • Jay...
  • Taken for 1 to 2 years
  • October 9, 2019

For Breast Cancer "After mastectomy surgery, stage 2, cancer in 2 lymph nodes inside mammary tissue. No chemo/radiation. Began letrozole, experienced hot flashes and insomnia. After one year, no hot flashes but sleep disruption. As I entered the 1.5-year mark taking letrozole, I began to have joint pain, deep aching, and less strength in hips and knees. As a former therapist, I switched to exercise in the pool as I could no longer tolerate joint pain with land-based exercise. By the 2-year mark, decreased stability when walking, difficulty climbing steps, and getting up from a chair or toilet. Prior to surgery, I had been walking 3 miles a day. Now, pain limits walking to a block. X-rays prior to surgery showed no significant arthritis in any joints. Now unable to get out of a chair without 8/10 pain. Stopped taking the medication, and 3 days later pain decreased from 8/10 to 5/10. 3 weeks after stopping the pill, pain is at 3/10, with lingering weakness in hips and knees. Mind is now less foggy. Quality of life is more important than continuing to take this medication."

1 / 10
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Frequently asked questions

  • Des...
  • Taken for less than 1 month
  • January 18, 2021

Letrozole for Female Infertility "Had my 1st round of Femara in December. I did ovulate for the 1st time that I’m aware of in a long time due to PCOS. I did end up pregnant, but sadly had a chemical pregnancy around 3 weeks. I’m thankful that it did work for us and I was able to conceive. Now is the hard part of figuring out where to go from here. Prayers and love to all!"

10 / 10
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  • Nan...
  • May 12, 2020

For Female Infertility "I was trying to get pregnant for 10 months. I went to an infertility specialist. Although I didn't have PCOS, I took letrozole for three months and got pregnant on the third cycle. Blessed with a baby. I don't understand, if I didn't have PCOS, how did it work? Another point to note is I was given a tablet of a local brand, and since I couldn't find that brand, I took Glaxosmith letrozole on the third cycle and got pregnant."

9 / 10
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  • NJg...
  • August 2, 2019

For Breast Cancer "Was on Letrozole for 7 weeks. Had debilitating side effects which included nausea, vomiting, appetite loss and weight loss, chronic fatigue syndrome type pain, bilateral swollen glands, joint pain, inflammation in any prior injury area, pain radiating from shoulders down to hands, anxiety including body tremors, agitation, depression, uncontrollable crying, feelings of hopelessness and helplessness, feeling of being hit by a truck, the flu, laundry kicked down three flights of stairs, no energy, need to sleep during the day, inability to sleep at night, hair loss and hair thinning just to name the top side effects. Voluntarily went off drug. Oncologist confirmed that some women just can't handle this drug and I am one of them. A month later I am back to normal. I am cleaning house, I am sewing, I am reading and swimming."

1 / 10
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  • Ali...
  • Taken for 6 months to 1 year
  • February 26, 2020

For Breast Cancer "I’ve had cancer twice. This second time, I have Stage 3 breast cancer and had to have chemotherapy. I’m on Letrozole, and have been on it since September 2019. Firstly, I can’t believe the pain I’m in. It’s got worse by the week/month. I’m a Pilates teacher and work every day, but I’m finding that there are things I can’t do now, as my hands and elbows are unbelievably painful. I can take a lot of pain, but this is bad. When I get out of bed or up from sitting, I can barely walk away. I also have groin pain and lower back pain, yet I’m fit and strong in every other way. This is getting me down, as I feel I’m on a slippery slope. It doesn’t help that I am high risk for another cancer, and that every pain worries me. I’m sorry that there are so many who are experiencing this."

5 / 10
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174 Report

More FAQ

  • Mba...
  • October 24, 2020

For Female Infertility "I used letrozole for the first time last year in Dec, conceived that same month, but sadly, I had a miscarriage at 21 weeks. Letrozole is my miracle drug with God's help. Used it again this cycle, I am hopeful it will conceive by God's Grace."

10 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • November 7, 2020

For Female Infertility "Has anyone used letrozole for 6 months, ovulated but not conceived?"

7 / 10
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460 Report
  • Anonymous
  • May 9, 2012

Letrozole for Breast Cancer, Metastatic "I've been taking Femara since the breast cancer was discovered in my lung - that has been 10 years this year. Two types of chemo failed to knock it out and as I was preparing for radiation, I started taking Femara. Within a month the tumor began to shrink and all that is left is scarring where it once was. I am so grateful to my doctor for recommending it to me. My other oncologist didn't even mention it. Needless to say I'm happy to be alive and enjoying life."

10 / 10
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  • Kes...
  • Taken for 1 to 2 years
  • April 29, 2019

For Breast Cancer "I have been on Letrozole for just about a year now. My comment is this. Not all generics are the same. When I first started, I had no side effects whatsoever. My oncologist couldn't believe it. Then after six months, my pharmacy switched brands and I began getting hives and severe joint pain; the new brand they were giving me was from Teva. I recently asked them if they could still get the brand (Breckenridge) that they had originally given me and they said yes. I'm now taking that one again. No hives, although I do still have some lingering joint pain. I've had the same experience on a couple other meds I take, i.e., when my pharmacy switches brands I've had problems. So I'm just saying that sometimes it's not the medication, but the manufacturer."

7 / 10
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  • ros...
  • February 8, 2012

Letrozole for Breast Cancer "I had many side effects, including hot flashes, confusion, stomach problems, vaginal dryness, tired easily, and bone weakening. On the bright side, I have had no recurrence, and it is now 12 years since my diagnosis with lymph node involvement."

7 / 10
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297 Report
  • Too...
  • Taken for 1 to 2 years
  • April 10, 2013

Letrozole for Breast Cancer "I have been taking Femara for almost two years now after my second surgery for estrogen receptor-positive breast cancer with no lymph nodes involved. Sure, there are multiple side effects, some pretty tough to deal with sometimes, but I am 66 years young and I love living. Give it a go and keep on living."

10 / 10
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  • Smi...
  • May 15, 2017

Letrozole for Breast Cancer "I've been taking Femara for a little over 5 months and have yet to experience any side effects whatsoever. I'd been warned about hot flashes, night sweats, joint pain, muscle pain, and so far nothing. I have two smallish tumors in one breast that we caught very early on, and at my 4-month ultrasound they've decreased by about 50%. I'll have a nipple-sparing mastectomy in about 2 weeks with DIEP flap reconstruction... the grossest part of this whole episode, in my opinion... followed by radiation. No chemo here, just a very healthy mostly vegetarian diet and tons of walking. I'm 69, 5'6'', 135 pounds, and so far consider myself about the luckiest cancer patient anywhere. Maybe I'll start feeling sick at some point, but not yet. Hang in there, ladies!!"

10 / 10
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  • Jee...
  • Taken for 1 to 6 months
  • September 26, 2020

For Female Infertility "I have been trying to conceive since 2018. Still no luck, had 2 miscarriages. Then the doc recommended a gynecologist. First, she gave me Clomid for 6 cycles. I had a very bad experience with horrible side effects and no luck with Clomid. Now she gave me Letrozole, it's my second round. I got my period on a 32-day cycle. Now let's see if a miracle will happen. Hoping to get positive news, wish me luck."

9 / 10
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  • Mom...
  • Taken for 1 to 6 months
  • December 6, 2021

Letrozole for Female Infertility "We tried for a year and a half to fall pregnant, then I discovered I had fibroids and had to have them surgically removed. Eight months later, I discovered I had gallstones and had to have my entire gallbladder removed, which was another setback. Four months after my gallbladder removal at 42 years old, the fertility professor who removed my fibroids did an ultrasound and said I have a few eggs, but my age is against me and I would need to go on Femara along with artificial insemination. My partner was not keen on AI, he was more inclined to let it happen naturally, believing it to be God's will. I was prescribed Femara to take two tablets for five days, starting on the third day of my period. I took it in September without AI and saw no results. I got my periods in October again and decided to give Femara one last try, after that, I was going to give up as I thought it was just not meant to be. In November 2021, I was one week late for my period. I took a pregnancy test, and to my delight, it was positive. There is hope, ladies! Wishing you all luck with baby dust. X"

10 / 10
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  • Anonymous
  • January 2, 2011

Letrozole for Breast Cancer "I am 46 years old, Stage IV MBC to lungs. I have been on Femara for 1.5 years. My tumors were 40% down after one year, and I am about to do the next CT scan soon. My side effects are minor muscle pain (and possibly some anxiety but may be unrelated). I have simultaneously adopted a vegan lifestyle and do regular exercise (yoga and walking). I have so much energy I don't know what to do with it. I don't gain weight either, and my muscle pain is usually gone after a brief stretch or walk. I highly recommend a vegan diet and exercise to those who want to minimize pain. Thanks all and good luck."

9 / 10
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  • Chi...
  • Taken for 1 to 6 months
  • January 26, 2015

Letrozole for Breast Cancer "Had Grade A Breast Cancer that was caught early. Had a mass and one lymph node removed. Went on Femara on Nov. 8, 2014, the day after I finished radiation. At first, I didn't notice anything. Slowly the pain in my feet started, then other joints in my body. I felt like I was having trouble getting air into my lungs. I started feeling like I was in a fog. I already had been diagnosed with depression years ago which was under control with medication. I started experiencing depression a couple of weeks ago which included waking up and crying. That turned into suicidal depression. Without pain medication, I couldn't move around well. The bottom of my feet were killing me. I work full time. I quit the Femara 2 days ago."

1 / 10
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  • Cin...
  • Taken for less than 1 month
  • January 6, 2021

For Female Infertility "I have been suffering from PCOS for a year now. Took Femara 2.5mg from day 3-7 of my cycle for 1 month. Well, I’m gonna be a mom. Hope this helps someone like it helped me."

10 / 10
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  • Lit...
  • July 9, 2009

Letrozole for Breast Cancer "I have been on Femara for 3 months. After taking Tamoxifen for approximately 2 years, which I could not tolerate any longer, my oncologist put me on Femara. While my hot flashes have pretty much disappeared, the joint and bone pain I am suffering is unbearable. My elbows, hands, fingers, knees, ankles, and feet are the worst. In the mornings, I cannot get out of bed. I take thyroid medicine in the morning and cannot open the bottle. It takes about 20 minutes before I can close my fingers or bend my toes. Nighttime is also bad. After sitting for short periods, I cannot get up. I have never felt better in my life except for the constant agonizing pain. I am a very active 49-year-old but feel like I am 90. This pain gets worse every day. I can only imagine what it will be like in 3 more months. I am seeing my oncologist this week and am going to tell him I am stopping this drug. I believe the quality of my life is more important than the quantity."

5 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • January 26, 2022

For Female Infertility "I have been diagnosed with PCOS more than ten years back. I had so many symptoms of PCOS struggling me these many years, which includes obesity, facial hair, depression, anxiety, etc. After marriage, I was about to start my fertility treatment but before that decided to lose weight. I lost almost 18 kgs within six months with a healthy diet and moderate exercise every day and regularized my period. Then I tried letrozole cycle day 3-7. First month no luck, second month no luck, third month finally, God answered my prayer. Now I am five weeks pregnant. Please pray for me. Baby dust to all the women reading my comment. Don't give up, don't lose hope. Try... Try... And try... Surely will succeed."

10 / 10
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  • Bil...
  • October 11, 2013

Letrozole for Breast Cancer "I have been on Femara for 3 years now, following 5 years on Tamoxifen as part of the Tango treatment for breast cancer. I have experienced severe joint pain, vaginal dryness, loss of libido, etc. But thought it was worth the effects in order to keep me 'cancer-free'. I was diagnosed with breast cancer in 2003. I have also had issues with bone problems i.e. broke my foot 4 years ago & chipped my knee joint. But hey, I'm still here. Keep persevering, girls!"

9 / 10
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  • Eri...
  • February 9, 2013

Letrozole for Breast Cancer "I have been on Femara for almost a year. At first, I had nearly constant hot flashes and night sweats. I was started on Effexor with nearly immediate relief. I have had increasingly painful joint and muscle pain, especially in my knees. Nothing seems to be helping much with that, and it has been a major detriment to my quality of life. I have recently added Magnesium, Fish Oil, and Glucosamine/Chondroitin to the Calcium and D3 I had been taking. Hopefully, this will ease the joint stiffness and pain. I am 52, and some days I feel 92. Still, I am cancer-free so far, so I will continue to take Femara."

7 / 10
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  • Cha...
  • August 24, 2021

Letrozole for Female Infertility "I struggled with getting pregnant for years! I found out I had PCOS in February of 2020, and my doctor put me on Femara in July of 2020. A week later, I was pregnant, and now I have a healthy 4-month-old baby girl! Love and baby dust to all, stay positive!"

10 / 10
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  • Anonymous
  • Taken for less than 1 month
  • September 14, 2021

For Female Infertility "Diagnosed with PCOS. Doctor prescribed 2.5mg of Letrozole with Provera-induced period. To God be the Glory, I'm 4 weeks pregnant off the first round (let the journey begin :) Praying that God blesses me with a healthy pregnancy and a healthy baby!"

10 / 10
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