Exemestane Disease Interactions
There are 2 disease interactions with exemestane.
Exemestane (applies to exemestane) osteoporosis
Moderate Potential Hazard, Moderate plausibility.
Reductions in bone mineral density (BMD) over time are seen with the use of exemestane. Women with osteoporosis or at risk of osteoporosis should have their BMD formally assessed by densitometry at treatment initiation. Monitoring for BMD loss is recommended, and treatment for it should be started as appropriate.
Exemestane (applies to exemestane) vitamin D deficiency
Moderate Potential Hazard, Moderate plausibility.
Routine assessment of vitamin D levels prior to the start of aromatase inhibitor treatment should be performed, due to the high prevalence of vitamin D deficiency in women with early breast cancer. Women with vitamin D deficiency should receive supplementation.
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Exemestane drug interactions
There are 100 drug interactions with exemestane.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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