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Exemestane Disease Interactions

There are 2 disease interactions with exemestane.

Moderate

Exemestane (applies to exemestane) osteoporosis

Moderate Potential Hazard, Moderate plausibility.

Reductions in bone mineral density (BMD) over time are seen with the use of exemestane. Women with osteoporosis or at risk of osteoporosis should have their BMD formally assessed by densitometry at treatment initiation. Monitoring for BMD loss is recommended, and treatment for it should be started as appropriate.

References

  1. "Product Information. Aromasin (exemestane)." Pharmacia and Upjohn (2001):
Moderate

Exemestane (applies to exemestane) vitamin D deficiency

Moderate Potential Hazard, Moderate plausibility.

Routine assessment of vitamin D levels prior to the start of aromatase inhibitor treatment should be performed, due to the high prevalence of vitamin D deficiency in women with early breast cancer. Women with vitamin D deficiency should receive supplementation.

References

  1. "Product Information. Aromasin (exemestane)." Pharmacia and Upjohn (2001):

Exemestane drug interactions

There are 79 drug interactions with exemestane.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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