Exemestane Dosage
Medically reviewed by Drugs.com. Last updated on Nov 8, 2024.
Applies to the following strengths: 25 mg
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Breast Cancer
25 mg orally once a day
Comment:
- This drug is not indicated for the treatment of breast cancer in premenopausal women.
Uses:
- Adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to exemestane for completion of a total of five consecutive years of adjuvant hormonal therapy.
- Treatment of advanced breast cancer in postmenopausal women whose disease has progressed following tamoxifen therapy.
Renal Dose Adjustments
No adjustment recommended
Liver Dose Adjustments
No adjustment recommended
Dose Adjustments
Patients taking exemestane with a potent CYP450 3A4 inducer such as rifampin or phenytoin: 50 mg once a day after a meal
Precautions
CONTRAINDICATIONS:
- Hypersensitivity to the active component or any of the ingredients
Safety and efficacy have not been established in patients younger than 18 years.
Consult WARNINGS section for additional precautions.
Dialysis
Data not available
Other Comments
Administration Advice:
- This drug should be taken after a meal.
Monitoring:
- Bone mineral density (BMD) in women with or at risk of developing osteoporosis
Patient advice:
- Exemestane may cause dizziness, asthenia, and somnolence. Patients should avoid driving or operating machinery if they experience these adverse effects.
- Advise females of reproductive potential of the potential risk to a fetus and to use effective contraception during therapy and for at least 1 month after the last dose.
- Advise females to contact their healthcare provider if they become pregnant, or if pregnancy is suspected, during treatment.
- Advise women not to breastfeed during treatment and for at least 1 month after the last dose.
Frequently asked questions
- Which is better - Aromasin or Femara?
- Aromasin vs Femara - how do they compare?
- How long do you need to take Aromasin?
- Should you take Aromasin with food?
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.