Comparing Evista vs Prolia
| Evista (raloxifene) | Prolia (denosumab) |
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| Evista (raloxifene) | Prolia (denosumab) |
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Prescription only
Evista is not a hormone but it mimics estrogen and may be used to treat osteoporosis in postmenopausal women or to lower the risk of invasive breast cancer in women with osteoporosis. Hot flashes are... View more |
Prescription only
Prolia is an injection that can be self-administered once every six months for the treatment of osteoporosis. It has been associated with an increased risk of fractures on discontinuation and... View more |
Related suggestions Osteoporosis
Popular comparisons
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| More about Evista (raloxifene) | More about Prolia (denosumab) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Evista has an average rating of 6.8 out of 10 from a total of 12 ratings on Drugs.com. 50% of reviewers reported a positive effect, while 25% reported a negative effect. |
Prolia has an average rating of 2.9 out of 10 from a total of 375 ratings on Drugs.com. 16% of reviewers reported a positive effect, while 76% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Evista side effects |
View all Prolia side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Evista prices |
View all Prolia prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
Other denosumab brands include: Bomyntra, Conexxence, Jubbonti, Osenvelt, Ospomyv, Stoboclo, Wyost, Xbryk, Xgeva View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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27.7 hours |
609.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 47 drugs are known to interact with Evista:
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A total of 311 drugs are known to interact with Prolia:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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December 09, 1997 |
June 01, 2010 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.