Estradiol Alternatives Compared
| Estradiol Remove Estradiol from your drug comparison | Premarin Remove Premarin from your drug comparison | Activella Remove Activella from your drug comparison |
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| Estradiol Remove Estradiol from your drug comparison | Premarin conjugated estrogens Remove Premarin from your drug comparison | Activella estradiol / norethindrone Remove Activella from your drug comparison | ||||||||||||||||||||||||
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Estradiol is a synthetic form of estrogen that may be given to women for a number of different indications, including the relief of menopausal symptoms or low estrogen levels. Its use is associated... View more |
Prescribed for Atrophic Vaginitis, Abnormal Uterine Bleeding, Atrophic Urethritis, Breast Cancer - Palliative, Hypoestrogenism, Oophorectomy, Osteoporosis, Postmenopausal Symptoms, Primary Ovarian... View more |
Prescribed for Postmenopausal Symptoms, Atrophic Vaginitis, Hypoestrogenism, Atrophic Urethritis. Activella may also be used for purposes not listed in this medication guide. |
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Prescription only |
Prescription only |
Prescription only |
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Ratings & Reviews |
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Drug Class |
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Side Effects |
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Commonly reported side effects include: cerebrovascular accident, infection, malignant neoplasm of breast, endometrium disease, headache, mastalgia. See the full estradiol side effects document. |
See the full Premarin side effects document. |
See the full Activella side effects document. |
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Pricing and Coupons* Prices are without insurance |
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View all estradiol prices |
View all Premarin prices |
View all Activella prices and generic prices |
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Generic Availability |
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Yes (this medicine) |
No |
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Dosage Form(s) Available |
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Brand Names |
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| Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more | Other conjugated estrogens brands include: Premarin Intravenous | Other estradiol / norethindrone brands include: Amabelz, CombiPatch, Ena, Lopreeza, Mimvey, Mimvey Lo | ||||||||||||||||||||||||
Half LifeThe half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. |
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16 hours |
N/A |
14 hours |
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CSA Schedule**View glossary of terms. |
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category |
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Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
Category X
Not for use in pregnancy
See the full Pregnancy Warnings document. |
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FDA Alerts |
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N/A |
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Drug Interactions |
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A total of 298 drugs are known to interact with estradiol:
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A total of 202 drugs are known to interact with Premarin:
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A total of 361 drugs are known to interact with Activella:
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Alcohol/Food/Lifestyle Interactions |
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions |
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First Approval Date |
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July 23, 1975 |
May 08, 1942 |
November 18, 1998 |
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WADA ClassView World Anti-Doping Agency classifications. |
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N/A |
N/A |
N/A |
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More Information |
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Consumer Resources |
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Professional Resources |
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Related Treatment Guide |
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.