Comparing Enbrel vs Rinvoq

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Enbrel etanercept

Rinvoq upadacitinib

Enbrel is a subcutaneous injection that is usually self-administered once or twice a week for inflammatory conditions such as rheumatoid arthritis, psoriasis, psoriatic arthritis, or ankylosing... View more

Prescribed for Rheumatoid Arthritis. Rinvoq may also be used for purposes not listed in this medication guide.

Prescription only

Ratings & Reviews

View all 250 reviews

View all 41 reviews

Drug Class

Antirheumatics

Side Effects

Common side effects include: infection, and injection site reaction.

See the full Enbrel side effects document.

See the full Rinvoq side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	4 mL
Dosage	50 mg/mL
Per Unit^*	$1,560.07 - $1,591.86
Cost^*	$6,240.26 - $6,367.42

View all Enbrel prices

Quantity	30 tablet, extended release
Dosage	15 mg
Per Unit^*	$184.08
Cost^*	$5,522.34

View all Rinvoq prices

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Generic Availability

Dosage Form(s) Available

Subcutaneous kit
Subcutaneous solution

Oral tablet, extended release

Brand Names

Other etanercept brands include: Erelzi, Eticovo

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

300 hours

14 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full Pregnancy Warnings document.

Summary unavailable.

See the full Pregnancy Warnings document.

Drug Interactions

A total of 401 drugs are known to interact with Enbrel:

238 major drug interactions (705 brand and generic names)
156 moderate drug interactions (606 brand and generic names)
7 minor drug interactions (33 brand and generic names)

A total of 406 drugs are known to interact with Rinvoq:

283 major drug interactions (824 brand and generic names)
116 moderate drug interactions (396 brand and generic names)
7 minor drug interactions (34 brand and generic names)

Alcohol/Food/Lifestyle Interactions

No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.

Disease Interactions

First Approval Date

November 02, 1998

August 16, 2019

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer