Comparing Doxepin vs Lyrica
| Doxepin | Lyrica (pregabalin) |
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| Doxepin | Lyrica (pregabalin) |
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Prescription only
Doxepin may be used to treat symptoms associated with anxiety or depression such as fear, guilt, sleep disturbances, tension, and worry. It is devoid of any euphoric effect and not associated with... View more |
Prescription only
Lyrica can help relieve nerve pain and control seizures but it is likely to cause drowsiness. Prescribed for Neuropathic Pain, Neuralgia, Fibromyalgia, Diabetic Peripheral Neuropathy, Postherpetic... View more |
Related suggestions Neuropathic Pain
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| More about Doxepin | More about Lyrica (pregabalin) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Doxepin has an average rating of 6.2 out of 10 from a total of 433 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 34% reported a negative effect. |
Lyrica has an average rating of 6.4 out of 10 from a total of 931 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 26% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Doxepin side effects |
View all Lyrica side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Doxepin prices |
View all Lyrica prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Adapin, Silenor | Other pregabalin brands include: Lyrica CR | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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25 hours |
6.3 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
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| Pregnancy Category | |||||||||||||||||
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Category N
Not classified
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 705 drugs are known to interact with Doxepin:
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A total of 287 drugs are known to interact with Lyrica:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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September 23, 1969 |
December 30, 2004 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.