Comparing Diclegis vs Zofran
| Diclegis (doxylamine / pyridoxine) | Zofran (ondansetron) |
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| Diclegis (doxylamine / pyridoxine) | Zofran (ondansetron) |
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Prescription only
Prescribed for Nausea/Vomiting of Pregnancy, Nausea/Vomiting. Diclegis may also be used for purposes not listed in this medication guide. |
Prescription only
Zofran is used to prevent nausea and vomiting caused by cancer chemotherapy, radiotherapy, or surgery. It is approved for use in adults and children over the age of 4 and is available as tablets... View more |
Related suggestions Nausea/Vomiting
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| More about Diclegis (doxylamine / pyridoxine) | More about Zofran (ondansetron) | ||||||||
| Ratings & Reviews | |||||||||
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Diclegis has an average rating of 7.0 out of 10 from a total of 116 ratings on Drugs.com. 58% of reviewers reported a positive effect, while 24% reported a negative effect. |
Zofran has an average rating of 8.0 out of 10 from a total of 271 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Diclegis side effects |
View all Zofran side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Diclegis prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other doxylamine / pyridoxine brands include: Bonjesta |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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12.5 hours |
4 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category A
Studies show no risk
See the full pregnancy warnings document. |
Category B
No proven risk in humans
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 320 drugs are known to interact with Diclegis:
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A total of 360 drugs are known to interact with Zofran:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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April 08, 2013 |
December 31, 1992 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.