Comparing Desyrel vs Pristiq
| Desyrel (trazodone) | Pristiq (desvenlafaxine) |
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| Desyrel (trazodone) | Pristiq (desvenlafaxine) |
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Prescription only
Prescribed for Fibromyalgia, Depression, Reflex Sympathetic Dystrophy Syndrome, Sedation, Major Depressive Disorder. Desyrel may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Major Depressive Disorder, Depression. Pristiq may also be used for purposes not listed in this medication guide. |
Related suggestions Depression
Major Depressive Disorder
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| More about Desyrel (trazodone) | More about Pristiq (desvenlafaxine) | ||||||||
| Ratings & Reviews | |||||||||
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Desyrel has an average rating of 6.3 out of 10 from a total of 40 ratings on Drugs.com. 45% of reviewers reported a positive effect, while 23% reported a negative effect. |
Pristiq has an average rating of 6.9 out of 10 from a total of 1129 ratings on Drugs.com. 60% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
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View all Desyrel side effects |
View all Pristiq side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
View all Pristiq prices |
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| Dosage Forms | |||||||||
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N/A |
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| Brand Names | |||||||||
| Other trazodone brands include: Raldesy |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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7.5 hours |
11 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 675 drugs are known to interact with Desyrel:
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A total of 483 drugs are known to interact with Pristiq:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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December 24, 1981 |
February 29, 2008 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.