Comparing Depo Provera vs Orilissa
| Depo Provera (medroxyprogesterone) | Orilissa (elagolix) |
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| Depo Provera (medroxyprogesterone) | Orilissa (elagolix) |
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Prescription only
Prescribed for Birth Control. Depo Provera may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Endometriosis. Orilissa may also be used for purposes not listed in this medication guide. |
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| More about Depo Provera (medroxyprogesterone) | More about Orilissa (elagolix) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Depo Provera has an average rating of 4.2 out of 10 from a total of 1969 ratings on Drugs.com. 27% of reviewers reported a positive effect, while 55% reported a negative effect. |
Orilissa has an average rating of 5.4 out of 10 from a total of 128 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 40% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Depo Provera side effects |
View all Orilissa side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Depo Provera prices |
View all Orilissa prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other medroxyprogesterone brands include: depo-subQ provera 104, Provera |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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401 hours |
6 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 255 drugs are known to interact with Depo Provera:
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A total of 375 drugs are known to interact with Orilissa:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 23, 1960 |
July 23, 2018 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.