Comparing Depakote vs Vraylar
| Depakote (divalproex sodium) | Vraylar (cariprazine) |
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| Depakote (divalproex sodium) | Vraylar (cariprazine) |
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Prescription only
Depakote may be used in the treatment of epilepsy and mania, and to prevent migraines; however, people taking Depakote should be monitored for potentially fatal side effects such as liver failure... View more |
Prescription only
Vraylar is an atypical antipsychotic that is effective for the treatment of schizophrenia and bipolar I disorder. Vraylar is usually well-tolerated and less likely than some other antipsychotics to... View more |
Related suggestions Bipolar Disorder
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| More about Depakote (divalproex sodium) | More about Vraylar (cariprazine) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Depakote has an average rating of 6.4 out of 10 from a total of 331 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 26% reported a negative effect. |
Vraylar has an average rating of 6.1 out of 10 from a total of 525 ratings on Drugs.com. 49% of reviewers reported a positive effect, while 32% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Depakote side effects |
View all Vraylar side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Depakote prices |
View all Vraylar prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other divalproex sodium brands include: Depakote ER, Depakote Sprinkles |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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16 hours |
504 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
When Treating Epilepsy And Manic Episodes Associated With Bipolar Disorder
Category X
Not for use in pregnancy
When Treating Migraine See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 425 drugs are known to interact with Depakote:
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A total of 578 drugs are known to interact with Vraylar:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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March 10, 1983 |
September 17, 2015 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.