Comparing Dasatinib vs Methotrexate

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Dasatinib	Methotrexate	Enter another drug to compare

Dasatinib

Methotrexate

Prescription only

Prescribed for Chronic Myelogenous Leukemia, Acute Lymphoblastic Leukemia, Leukemia. Dasatinib may also be used for purposes not listed in this medication guide.

Prescription only

Methotrexate may be considered for the treatment of psoriasis, rheumatoid arthritis, polyarticular juvenile idiopathic arthritis (pJIA), mycosis fungoides, and certain cancers, such as ALL or... View more

More about Dasatinib

More about Methotrexate

Ratings & Reviews

Dasatinib has an average rating of 7.7 out of 10 from a total of 27 ratings on Drugs.com. 70% of reviewers reported a positive effect, while 15% reported a negative effect.

Methotrexate has an average rating of 6.5 out of 10 from a total of 339 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 24% reported a negative effect.

View all 27 reviews

View all 339 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

View all Dasatinib side effects

Nausea (14.7%)
Tiredness (13.9%)
Fatigue (11.8%)
Hair loss (8.6%)
Pain (6.8%)
Headaches (5.6%)
Loss of appetite (5.0%)

View all Methotrexate side effects

Drug Class

BCR-ABL tyrosine kinase inhibitors

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	60 tablet
Strength	20 mg
Per unit^*	$134.81
Cost^*	$8,088.76

View all Dasatinib prices

Quantity	20 each
Strength	2.5 mg
Per unit^*	$1.52
Cost^*	$30.31

View all Methotrexate prices

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Dosage Forms

Oral tablet

Injectable powder for injection
Injectable solution
Oral tablet

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

5 hours

15 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category D Positive evidence of risk

See the full pregnancy warnings document.

Category X Not for use in pregnancy

See the full pregnancy warnings document.

Drug Interactions

A total of 817 drugs are known to interact with Dasatinib:

245 major drug interactions (873 brand and generic names)
553 moderate drug interactions (2133 brand and generic names)
19 minor drug interactions (41 brand and generic names)

A total of 731 drugs are known to interact with Methotrexate:

148 major drug interactions (678 brand and generic names)
568 moderate drug interactions (2752 brand and generic names)
15 minor drug interactions (47 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Do not consume grapefruit or grapefruit juice during treatment with dasatinib. Grapefruit juice... View more

Caffeine may reduce the effectiveness of methotrexate in the treatment of arthritis. If you are... View more
Methotrexate may cause liver problems, and using it with other medications that can also affect the... View more

Disease Interactions

First Approval Date

June 28, 2006

December 07, 1953

WADA Class View classifications

N/A

More Information

Patient Resources

Dasatinib uses

Methotrexate uses

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Dasatinib vs Methotrexate

See also:

Hydrea

Gleevec

Dupixent

Sprycel

Tasigna

Cytoxan

Scemblix

Bosulif

Nilotinib

Imatinib

Further information

Comparing Dasatinib vs Methotrexate

See also:

Further information

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