Comparing Cymbalta vs Wellbutrin
| Cymbalta (duloxetine) | Wellbutrin (bupropion) |
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| Cymbalta (duloxetine) | Wellbutrin (bupropion) |
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Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Prescription only
Wellbutrin was used to treat major depressive disorder (MDD, Wellbutrin XL, SR) or seasonal affective disorder (SAD, Wellbutrin XL only), but the brand Wellbutrin has been discontinued. Generic... View more |
Related suggestions Depression
Major Depressive Disorder
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| More about Cymbalta (duloxetine) | More about Wellbutrin (bupropion) | ||||||||
| Ratings & Reviews | |||||||||
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Cymbalta has an average rating of 6.3 out of 10 from a total of 1908 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
Wellbutrin has an average rating of 6.8 out of 10 from a total of 765 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 22% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||
View all Cymbalta side effects |
View all Wellbutrin side effects |
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| Drug Class | |||||||||
| Generic Availability | |||||||||
| Lower cost generic approved | |||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||
View all Cymbalta prices |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | |||||||||
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| Brand Names | |||||||||
| Other duloxetine brands include: Drizalma Sprinkle, Irenka | Other bupropion brands include: Aplenzin, Budeprion, Budeprion SR, Forfivo XL, Wellbutrin SR, Wellbutrin XL | ||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||
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17 hours |
30 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||
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A total of 635 drugs are known to interact with Cymbalta:
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A total of 562 drugs are known to interact with Wellbutrin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||
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| Disease Interactions | |||||||||
| First Approval Date | |||||||||
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N/A |
December 30, 1985 |
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| WADA Class View classifications | |||||||||
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N/A |
N/A |
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| More Information | |||||||||
| Patient Resources | |||||||||
| Professional Resources | |||||||||
| Related Treatment Guide | |||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.