Comparing Cymbalta vs Lexapro
| Cymbalta (duloxetine) | Lexapro (escitalopram) |
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| Cymbalta (duloxetine) | Lexapro (escitalopram) |
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Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Prescription only
Lexapro is an effective antidepressant that may have less potential for adverse effects than other SSRI antidepressants. Prescribed for Anxiety, Major Depressive Disorder, Generalized Anxiety... View more |
Related suggestions Depression
Major Depressive Disorder
Generalized Anxiety Disorder
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| More about Cymbalta (duloxetine) | More about Lexapro (escitalopram) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Cymbalta has an average rating of 6.3 out of 10 from a total of 1891 ratings on Drugs.com. 54% of reviewers reported a positive effect, while 30% reported a negative effect. |
Lexapro has an average rating of 7.6 out of 10 from a total of 2359 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 15% reported a negative effect. |
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| Side Effects | |||||||||||||||||
| Generic Availability | |||||||||||||||||
| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Cymbalta prices |
View all Lexapro prices |
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| Dosage Forms Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other duloxetine brands include: Drizalma Sprinkle, Irenka |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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17 hours |
32 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 622 drugs are known to interact with Cymbalta:
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A total of 700 drugs are known to interact with Lexapro:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
August 14, 2002 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.