Comparing Cymbalta vs Lexapro
| Cymbalta | Lexapro |
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| Cymbalta (duloxetine) | Lexapro (escitalopram) |
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Prescription only
Cymbalta has antidepressant, anti-anxiety, and pain-relieving properties; however, it has been associated with a discontinuation syndrome on withdrawal even when tapered. Prescribed for Back Pain... View more |
Prescription only
Lexapro is an effective antidepressant that may have less potential for adverse effects than other SSRI antidepressants. Prescribed for Anxiety, Generalized Anxiety Disorder, Major Depressive... View more |
Related suggestions Depression
Major Depressive Disorder
Generalized Anxiety Disorder
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| More about Cymbalta (duloxetine) | More about Lexapro (escitalopram) | ||||||||||||||||
| Generic Status | |||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Cymbalta has an average rating of 6.2 out of 10 from a total of 1825 ratings on Drugs.com. 53% of reviewers reported a positive effect, while 30% reported a negative effect. |
Lexapro has an average rating of 7.5 out of 10 from a total of 2224 ratings on Drugs.com. 68% of reviewers reported a positive effect, while 16% reported a negative effect. |
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| Drug Class | |||||||||||||||||
| Side Effects | |||||||||||||||||
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Common side effects include:
See also: Cymbalta side effects in more detail. |
Common side effects include:
See also: Lexapro side effects in more detail. |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Cymbalta prices and generic prices |
View all Lexapro prices and generic prices |
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| Dosage Form(s) Available | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Other duloxetine brands include: Drizalma Sprinkle, Irenka |
N/A |
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| Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
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17 hours |
32 hours |
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| CSA Schedule ** View glossary of terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 578 drugs are known to interact with Cymbalta:
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A total of 677 drugs are known to interact with Lexapro:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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N/A |
August 14, 2002 |
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| WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.