Comparing Climara vs Estradot 50

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Climara (estradiol)	Estradot 50 (estradiol)	Enter another drug to compare

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Climara (estradiol)	Estradot 50 (estradiol)	Enter another drug to compare
Prescription only Prescribed for Atrophic Vaginitis, Postmenopausal Symptoms, Atrophic Urethritis, Oophorectomy, Hypoestrogenism, Primary Ovarian Failure, Prevention of Osteoporosis. Climara may also be used for... View more	Prescription only Prescribed for Postmenopausal Symptoms. Estradot 50 may also be used for purposes not listed in this medication guide.	Related suggestions Postmenopausal Symptoms Estradiol Premarin Estradiol Patch Activella Prempro Estrace
More about Climara (estradiol)	More about (estradiol)
Ratings & Reviews
Climara has an average rating of 6.3 out of 10 from a total of 62 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 27% reported a negative effect.	Estradot 50 has an average rating of 8.8 out of 10 from a total of 4 ratings on Drugs.com. 75% of reviewers reported a positive effect, while 0% reported a negative effect.
View all 62 reviews	View all 4 reviews
Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.
Hot flashes (11.3%) Night sweats (8.1%) Insomnia (6.5%) Anxiety (4.8%) Itching (4.8%) View all Climara side effects	View all Estradot 50 side effects
Drug Class
Estrogens	Estrogens
Generic Availability
Lower cost generic approved	Lower cost generic approved
Pricing and Coupons * Prices are without insurance
We could not find an exact match for this medicine. Try searching the Price Guide directly.	We could not find an exact match for this medicine. Try searching the Price Guide directly.
Get free Discount Card	Get free Discount Card

Dosage Forms
N/A	N/A
Brand Names
Other estradiol brands include: Alora, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more	Other estradiol brands include: Alora, Climara, Delestrogen, Depo-Estradiol, Divigel, Dotti, Elestrin, Estra Pellets, Estrace, Estraderm, Estradiol Patch, Estrogel, Evamist, Femring, Lyllana, Menostar, Minivelle, Vivelle-Dot View more
Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.
16 hours	16 hours
CSA Schedule ¹ View glossary of CSA terms
N Not a controlled drug Is not subject to the Controlled Substances Act.	N Not a controlled drug Is not subject to the Controlled Substances Act.
Pregnancy Category
X Category X Not for use in pregnancy See the full pregnancy warnings document.	X Category X Not for use in pregnancy See the full pregnancy warnings document.
Drug Interactions
A total of 389 drugs are known to interact with Climara: 34 major drug interactions (84 brand and generic names) 335 moderate drug interactions (1243 brand and generic names) 20 minor drug interactions (98 brand and generic names)	A total of 389 drugs are known to interact with Estradot 50: 34 major drug interactions (84 brand and generic names) 335 moderate drug interactions (1243 brand and generic names) 20 minor drug interactions (98 brand and generic names)
Alcohol/Food/Lifestyle Interactions
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.	No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
Disease Interactions
Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests	Abnormal vaginal bleeding Carcinomas (estrogenic) Hypercalcemia in breast cancer Hypertension Thromboembolism/cardiovascular Hepatic neoplasms Angioedema Gallbladder disease Hypercalcemia Hyperlipidemia Liver disease Melasma Depression Fluid retention Glucose intolerance Retinal thrombosis Thyroid function tests
First Approval Date
December 22, 1994	N/A
WADA Class View classifications
N/A	N/A
More Information
Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings Support group En español	Side effects Drug interactions Dosage Pregnancy warnings Breastfeeding warnings
Patient Resources
Climara uses	N/A
Professional Resources
Prescribing information	N/A
Related Treatment Guide
Atrophic Vaginitis Postmenopausal Symptoms Atrophic Urethritis Oophorectomy Hypoestrogenism Primary Ovarian Failure Prevention of Osteoporosis	Postmenopausal Symptoms

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

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Medical Disclaimer

Comparing Climara vs Estradot 50

See also:

Fosamax

Premarin

Ozempic

Reclast

Estrace

Zometa

Atelvia

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Lo Loestrin Fe

Evista

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Comparing Climara vs Estradot 50

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