Comparing Botox vs Amitriptyline
Botox | Amitriptyline |
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Botox (onabotulinumtoxinA) | Amitriptyline |
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Prescription only
Botox is approved to treat many conditions, such as chronic migraine, involuntary muscle contractions or twitching, excessive sweating, increased saliva, and overactive bladder to name a few. Botox... View more |
Prescription only
Amitriptyline is an effective antidepressant but it may cause drowsiness initially and a withdrawal syndrome with abrupt discontinuation. It may be used off-label to treat other conditions such as... View more |
Related suggestions Migraine Prevention (Migraine Prophylaxis)
Hyperhidrosis
Urinary Incontinence
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More about Botox (onabotulinumtoxinA) | More about Amitriptyline | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Botox has an average rating of 5.6 out of 10 from a total of 467 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 42% reported a negative effect. |
Amitriptyline has an average rating of 7.6 out of 10 from a total of 1779 ratings on Drugs.com. 69% of reviewers reported a positive effect, while 16% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Botox side effects in more detail. |
See also: amitriptyline side effects in more detail. |
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Generic Availability | |||||||||||||||||
N/A |
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Botox prices |
View all amitriptyline prices |
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Dosage Forms Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other onabotulinumtoxinA brands include: Botox Cosmetic |
N/A |
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Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
N/A |
16 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 119 drugs are known to interact with Botox:
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A total of 709 drugs are known to interact with amitriptyline:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
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First Approval Date | |||||||||||||||||
December 09, 1991 |
April 07, 1961 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
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** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.