Comparing Baclofen vs Xenazine

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
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Baclofen

Xenazine tetrabenazine

Baclofen relieves muscle spasm associated with multiple sclerosis and spinal cord injury or disease, but its use is limited by its ability to cause sedation and increase seizure risk. Prescribed for... View more

Prescribed for Huntington's Disease. Xenazine may also be used for purposes not listed in this medication guide.

Prescription only

Ratings & Reviews

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Drug Class

Skeletal muscle relaxants

VMAT2 inhibitors

Side Effects

Commonly reported side effects include: drowsiness.

See the full baclofen side effects document.

Common side effects include: drowsiness, sedated state, bradykinesia, hypertonia, muscle rigidity, depression, exacerbation of depression, akathisia, and restlessness.

See the full Xenazine side effects document.

Pricing and Coupons

* Prices are without insurance

Quantity	50 each
Dosage	10 mg
Per Unit^*	$0.63
Cost^*	$31.28

View all baclofen prices

Quantity	112 tablet
Dosage	12.5 mg
Per Unit^*	$157.67
Cost^*	$17,658.74

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Generic Availability

Yes (this medicine)

Yes

Dosage Form(s) Available

Intrathecal solution
Oral tablet

Oral tablet

Brand Names

Gablofen, Lioresal, Lioresal Intrathecal, Ozobax

N/A

Half Life

The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value.

6.8 hours

8 hours

CSA Schedule**

View glossary of terms.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

Category C Risk cannot be ruled out

See the full Pregnancy Warnings document.

FDA Alerts

FDA Alerts (3)

N/A

Drug Interactions

A total of 347 drugs are known to interact with baclofen:

25 major drug interactions (140 brand and generic names)
321 moderate drug interactions (1267 brand and generic names)
1 minor drug interactions (2 brand and generic names)

A total of 501 drugs are known to interact with Xenazine:

100 major drug interactions (303 brand and generic names)
399 moderate drug interactions (1700 brand and generic names)
2 minor drug interactions (11 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Alcohol can increase the nervous system side effects of baclofen such as dizziness, drowsiness, and... View more

Alcohol can increase the nervous system side effects of tetrabenazine such as dizziness,... View more

Disease Interactions

First Approval Date

November 22, 1977

August 15, 2008

WADA Class

View World Anti-Doping Agency classifications.

N/A

More Information

** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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