Comparing Atropine / Diphenoxylate vs Loperamide
| Atropine / diphenoxylate | Loperamide |
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| Atropine / diphenoxylate | Loperamide |
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Prescription only
Prescribed for Diarrhea. Atropine / diphenoxylate may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Loperamide effectively treats diarrhea in adults and children over the age of 2 years by slowing down the movement of the bowel. Children are especially sensitive to its effects, especially if they... View more |
Related suggestions |
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| More about Atropine / diphenoxylate | More about Loperamide | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Atropine / diphenoxylate has an average rating of 8.2 out of 10 from a total of 68 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 13% reported a negative effect. |
Loperamide has an average rating of 8.4 out of 10 from a total of 93 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 10% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Loperamide side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Atropine / diphenoxylate prices |
View all Loperamide prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Logen, Lomanate, Lomotil | A-D Anti-Diarrheal, Anti-Diarrheal, Diamode, Diar-Aid, Imodium, Imodium A-D, Kaopectate II, Neo-Diaral, Up and Up Anti-Diarrheal Solution View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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14 hours |
10.8 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 315 drugs are known to interact with Atropine / diphenoxylate:
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A total of 353 drugs are known to interact with Loperamide:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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September 15, 1960 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.