Comparing Atropine / Diphenoxylate vs Loperamide
| Atropine / diphenoxylate | Loperamide |
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| Atropine / diphenoxylate | Loperamide |
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Prescription only
Prescribed for Diarrhea. Atropine / diphenoxylate may also be used for purposes not listed in this medication guide. |
Prescription and OTC
Loperamide effectively treats diarrhea in adults and children over the age of 2 years by slowing down the movement of the bowel. Children are especially sensitive to its effects, especially if they... View more |
Related suggestions |
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| More about Atropine / diphenoxylate | More about Loperamide | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Atropine / diphenoxylate has an average rating of 8.2 out of 10 from a total of 68 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 13% reported a negative effect. |
Loperamide has an average rating of 8.4 out of 10 from a total of 92 ratings on Drugs.com. 76% of reviewers reported a positive effect, while 10% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Loperamide side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Atropine / diphenoxylate prices |
View all Loperamide prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Logen, Lomanate, Lomotil | A-D Anti-Diarrheal, Anti-Diarrheal, Diamode, Diar-Aid, Imodium, Imodium A-D, Kaopectate II, Neo-Diaral, Up and Up Anti-Diarrheal Solution View more | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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14 hours |
10.8 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 315 drugs are known to interact with Atropine / diphenoxylate:
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A total of 352 drugs are known to interact with Loperamide:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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September 15, 1960 |
N/A |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.