Comparing Alprazolam vs Doxepin
| Alprazolam | Doxepin |
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| Alprazolam | Doxepin |
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Prescription only
Alprazolam is used for the acute treatment of generalized anxiety disorder (GAD) and panic disorder (PD) in adults. Carries boxed warnings for opioid interactions, abuse/addiction, and... View more |
Prescription only
Doxepin treats major depression and anxiety in adults, particularly with neurosis, alcoholism, or depressive disorders. Low-dose formulation (Silenor) treats insomnia; topical cream relieves... View more |
Related suggestions |
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| More about Alprazolam | More about Doxepin | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Alprazolam has an average rating of 8.6 out of 10 from a total of 1503 ratings on Drugs.com. 83% of reviewers reported a positive effect, while 8% reported a negative effect. |
Doxepin has an average rating of 6.2 out of 10 from a total of 433 ratings on Drugs.com. 52% of reviewers reported a positive effect, while 34% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
View all Alprazolam side effects |
View all Doxepin side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Alprazolam prices |
View all Doxepin prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Alprazolam Intensol, Xanax, Xanax XR | Adapin, Silenor | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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20 hours |
25 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Some potential for abuse
Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category N
Not classified
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 565 drugs are known to interact with Alprazolam:
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A total of 707 drugs are known to interact with Doxepin:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
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| First Approval Date | |||||||||||||||||
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October 16, 1981 |
September 23, 1969 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.