Comparing Alfuzosin vs Silodosin

View side-by-side comparisons of medication uses, ratings, cost, side effects and interactions.
Alfuzosin	Silodosin	Enter another drug to compare

Alfuzosin

Silodosin

Prescription only

Prescribed for Benign Prostatic Hyperplasia. Alfuzosin may also be used for purposes not listed in this medication guide.

Prescription only

Prescribed for Benign Prostatic Hyperplasia. Silodosin may also be used for purposes not listed in this medication guide.

More about Alfuzosin

More about Silodosin

Ratings & Reviews

Alfuzosin has an average rating of 5.5 out of 10 from a total of 82 ratings on Drugs.com. 39% of reviewers reported a positive effect, while 37% reported a negative effect.

Silodosin has an average rating of 5.8 out of 10 from a total of 128 ratings on Drugs.com. 40% of reviewers reported a positive effect, while 27% reported a negative effect.

View all 82 reviews

View all 128 reviews

Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified.

Tiredness (19.5%)
Dizziness (11.0%)
Sexual dysfunction (11.0%)
Headaches (9.8%)
Fatigue (6.1%)
Increased heart rate (4.9%)
Weakness (4.9%)

View all Alfuzosin side effects

Ejaculation problems (25.8%)
Sexual dysfunction (16.4%)
Dizziness (10.2%)
Runny nose (7.8%)
Diarrhea (3.9%)
Headaches (3.9%)
Stuffy nose (3.9%)

View all Silodosin side effects

Drug Class

Alpha blockers

Alpha blockers

Generic Availability

Lower cost generic

Pricing and Coupons * Prices are without insurance

Quantity	30 tablet, extended release
Strength	10 mg
Per unit^*	$0.44
Cost^*	$13.24

View all Alfuzosin prices

Quantity	30 capsule
Strength	8 mg
Per unit^*	$1.25 - $2.95
Cost^*	$37.41 - $88.52

View all Silodosin prices

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Dosage Forms

Oral tablet, extended release

Oral capsule

Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value.

10 hours

21.37 hours

CSA Schedule ¹ View glossary of CSA terms

Not a controlled drug

Is not subject to the Controlled Substances Act.

Not a controlled drug

Is not subject to the Controlled Substances Act.

Pregnancy Category

Category B No proven risk in humans

See the full pregnancy warnings document.

Category B No proven risk in humans

See the full pregnancy warnings document.

Drug Interactions

A total of 497 drugs are known to interact with Alfuzosin:

95 major drug interactions (254 brand and generic names)
396 moderate drug interactions (1581 brand and generic names)
6 minor drug interactions (17 brand and generic names)

A total of 412 drugs are known to interact with Silodosin:

32 major drug interactions (74 brand and generic names)
379 moderate drug interactions (1355 brand and generic names)
1 minor drug interactions (2 brand and generic names)

Alcohol/Food/Lifestyle Interactions

Food can enhance the levels of alfuzosin in your body. Alfuzosin should be taken just after eating... View more
Ask your doctor before using alcohol together with alfuzosin. Using alcohol with alfuzosin can... View more

Taking silodosin with food can reduce the risk and/or severity of side effects. Therefore... View more
Ask your doctor before using alcohol together with silodosin. Using alcohol with silodosin can... View more

Disease Interactions

First Approval Date

June 12, 2003

October 08, 2008

WADA Class View classifications

N/A

More Information

Patient Resources

Professional Resources

¹ The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

Comparing Alfuzosin vs Silodosin

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