Comparing Aclasta vs Prolia
| Aclasta (zoledronic acid) | Prolia (denosumab) |
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|---|
| Aclasta (zoledronic acid) | Prolia (denosumab) |
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|---|---|---|
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Prescription only
Prescribed for Osteoporosis, Paget's Disease, Osteolytic Bone Metastases of Solid Tumors, Hypercalcemia of Malignancy, Osteolytic Bone Lesions of Multiple Myeloma. Aclasta may also be used for... View more |
Prescription only
Prolia is an injection that can be self-administered once every six months for the treatment of osteoporosis. It has been associated with an increased risk of fractures on discontinuation and... View more |
Related suggestions Osteoporosis
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| More about Aclasta (zoledronic acid) | More about Prolia (denosumab) | |
| Ratings & Reviews | ||
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Aclasta has an average rating of 4.5 out of 10 from a total of 31 ratings on Drugs.com. 29% of reviewers reported a positive effect, while 48% reported a negative effect. |
Prolia has an average rating of 2.9 out of 10 from a total of 375 ratings on Drugs.com. 16% of reviewers reported a positive effect, while 76% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | ||
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View all Aclasta side effects |
View all Prolia side effects |
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| Drug Class | ||
| Generic Availability | ||
| Lower cost generic approved |
N/A |
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| Pricing and Coupons * Prices are without insurance | ||
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We could not find an exact match for this medicine. Try searching the Price Guide directly. |
We could not find an exact match for this medicine. Try searching the Price Guide directly. |
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| Dosage Forms | ||
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N/A |
N/A |
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| Brand Names | ||
| Other zoledronic acid brands include: Reclast, Zometa | Other denosumab brands include: Bomyntra, Conexxence, Jubbonti, Osenvelt, Ospomyv, Stoboclo, Wyost, Xbryk, Xgeva View more | |
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | ||
|
N/A |
609.6 hours |
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| CSA Schedule 1 View glossary of CSA terms | ||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | ||
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Category D
Positive evidence of risk
See the full pregnancy warnings document. |
Category X
Not for use in pregnancy
See the full pregnancy warnings document. |
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| Drug Interactions | ||
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A total of 126 drugs are known to interact with Aclasta:
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A total of 312 drugs are known to interact with Prolia:
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| Alcohol/Food/Lifestyle Interactions | ||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | ||
| First Approval Date | ||
|
N/A |
June 01, 2010 |
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| WADA Class View classifications | ||
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N/A |
N/A |
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| More Information | ||
| Patient Resources | ||
| Professional Resources | ||
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N/A |
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| Related Treatment Guide | ||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.