Trintellix and Anxiety: What Users Say (Page 4)

• 1Ba...
• October 26, 2016

For Depression "I've been taking anti-depression meds for about 7 years. Was on Celexa for 3 of those years, and it was great. I worked my way up to 150 mg, and it just seemed to quit on me altogether, so I was prescribed Zoloft by my doctor, and I'm not happy with it. Had to add Sertraline to it, also prescribed by my doc. I finally got the courage to go see a therapist, and he is slowly transitioning me over to Trillexine. I'm on Day 5 of coming off Lexapro and slowly moving to the Trillexine. Not that easy. I'm on .5 Trillexine and 150 mg of Lexapro. Seem to be having panic attacks and anxiety. I'm able to control it a little better, but I'm ready for this anxiety to be gone from my body. I'm hoping this drug does the trick."

• Anonymous
• Taken for less than 1 month
• November 27, 2021

For Depression "This is the worst drug any big pharma could ever put on the market. I'm a 52-year-old woman who tried this for light depression and anxiety. My doctor gave me free trials. Oh dear God, this drug must be taken off the market. It gave me severe increased anxiety, I almost went out of my mind. I had a very heavy head feeling and a terrible uneasy feeling for days. My heart was racing and I had increased pain and heaviness in it-just horrendous. Take this drug off the market, I couldn't imagine any young adult going through this with this particular medication, it would be horrifying for them. Any company that gives free samples of medicine should be held responsible for their terrible trial runs using people as guinea pigs!"

• Anonymous
• Taken for less than 1 month
• November 27, 2021

For Depression "This is the worst drug any big pharma could ever put on the market. I'm a 52-year-old woman who tried this for light depression and anxiety. My doctor gave me free trials. Oh dear God, this drug must be taken off the market. It gave me severe increased anxiety, I almost went out of my mind. I had a very heavy head feeling and a terrible uneasy feeling for days. My heart was racing and I had increased pain and heaviness in it-just horrendous. Take this drug off the market, I couldn't imagine any young adult going through this with this particular medication, it would be horrifying for them. Any company that gives free samples of medicine should be held responsible for their terrible trial runs using people as guinea pigs!"

• 35-...
• February 16, 2021

For Depression "I was suffering from OCD and anxiety. My doctor put me on Trintellix 10 mg/day. I took it for about a month, but my anxiety got worse after a few days. I contacted my doctor and let him know that this medication has made me more anxious, but he said that it is not Trintellix causing these symptoms and your anxiety is too high. He increased the dose to 20 mg/day. After a few days, the pins-and-needles sensation became a permanent issue and I had significant apprehension, got insomnia, stomach pain, and itchy skin. My psychiatrist was still insisting that I should give this medication at least one more month. So, I decided to change my psychiatrist. The new doctor asked me to gradually reduce the Trintellix dose and get rid of it within two weeks. He prescribed me Clonazepam 0.5 mg twice a day. After a few days, I am feeling much better. Everything has improved, and I am getting my life back. I know that Clonazepam might not be a reasonable long-term solution, but Trintellix was a real nightmare."

• Die...
• Taken for less than 1 month
• July 13, 2019

For Major Depressive Disorder "I have only been on Trintellix for just over a week, at 10 mg, and have been struggling with insomnia since my first dose. I was taking 150 mg of Zoloft, and it was working very well for my depression, but I still dealt with a lot of fatigue, so I thought I'd try the Trintellix. Along with the insomnia, my mood has gotten worse, I have increased anxiety, and my fatigue has obviously worsened due to no sleep from the insomnia. I did not have any issues with nausea, as so many others have had. I am very torn as to whether I should continue taking the Trintellix because I know just over a week is not nearly enough time to get the full effect and results, but I definitely feel like I have taken a big step backward from how I felt on the Zoloft. I messaged my doctor to get his thoughts but think going back to Zoloft may be the best plan for me. Trintellix only cost me $10 per month with the online discount card, so cost was not an issue."

• Sas...
• Taken for 1 to 6 months
• January 20, 2021

For Depression "It’s an okay medication for anxiety. Does cause some digestive issues. I’ve been on Citalopram, Zoloft, Wellbutrin, Mirtazapine, etc. This one seems to be the best tolerated for me. Zoloft and Citalopram took away my sex drive. Wellbutrin made me anxious, suicidal, and an insomniac. Mirtazapine is a great medication. Prob the best one, but the weight gain isn’t for me. I like to have an active sex life, and getting fat isn’t on my list. My doctor recommended Trintellix. It does limit my sex drive a little (thankfully, I have a high sex drive), but I am still horny and happy. I do struggle to sleep though, so I’m also on Trazodone. If you are skinny, go for Mirtazapine, it’s by far the best for anxiety."

• Hal...
• Taken for less than 1 month
• May 22, 2018

For Depression "I've been taking Trintellix for the past 4-5 days. My anxiety is through the roof, and I'm very angry and sad. I'm on 5 mg, also take Clonazepam, and it's not helping. It's causing trouble in my home life. I'm not sure what to do."

• odi...
• February 11, 2017

For Major Depressive Disorder "I had been on Celexa from 2002 to 2014, 20 mg a day. My doctor told me about Brintellix (now Trintellix), and I switched to it about 2 and a half years ago. Since I am also on Wellbutrin, I only needed 5 mg of Trintellix a day. Can't say that it makes me feel perfect, but it helped with my depression and anxiety disorder. Today is the first day that I have not been on Trintellix, but still on Wellbutrin, and I am feeling about as even keel as I have in a while, not experiencing anxiety or depression at all. I'll see how it goes in the next few days, but if I keep on feeling like this, I will stay just on the Wellbutrin and not go back to Trintellix."

• mel...
• Taken for less than 1 month
• October 23, 2021

For Depression "My doctor started me on 5 mg for two weeks, to be followed by 10 mg for two weeks. The first two weeks were great. Only mild diarrhea, mild headaches, and mild to moderate dizziness. I just went up to 10 mg this morning, and it has not been good for me. I am suicidal, don't want to do anything at all, major anxiety and restlessness. I am going back down to 5 mg. Besides this, it has been so good for my depression. I want to get up in the morning, and it has also helped with intrusive thoughts. They are not gone entirely but are a lot better to manage. All in all, I'm having a good experience with Trintellix. I have free samples and am not sure what the cost to me is yet."

• Zar...
• Taken for less than 1 month
• April 19, 2021

For Depression "I wrote a detailed explanation, which was apparently too long for this forum, so long story short, 1st week was good, 2nd week developed extreme anxiety, high BP, high heart rate, insomnia, and horrible akathisia. Had high hopes, but ended up being a nightmare. Akathisia was a nightmare. Will probably work for most, but beware that it may cause akathisia."

• Anonymous
• May 6, 2018

For Depression "From the start, I can't sleep. My stomach feels like it's on fire, I can't eat or am throwing up when I do eat. I've lost 14 lbs in one month due to not eating. My heart beats super fast, I'm dizzy and unsteady, and the worst of all, it does nothing for anxiety. It has made it worse. Also, the drug interactions, I throw up the pain medication for my back, codeine. You can't take basic medications for colds, allergies, headache, or body ache. After taking or trying to take 20 mg for a month, I just want to crawl in a hole. This is NOT a good medicine. Had a slight improvement with depression, but not worth it."

• BGa...
• Taken for 1 to 6 months
• September 5, 2019

"Word of caution to anyone who plans on using Trintellix to treat generalized or social anxiety - not only did this medication not improve my symptoms, I believe it has made them worse. I was formerly on 50 mg of Zoloft for a number of years and was doing well on it minus the brain fog and detachment issues that many experience. My doctor suggested I try this drug to get rid of some of those symptoms... In reality, I wake up with a slight headache every day (magnified 10x after drinking), am more anxious, and have had tightening in the chest. Long story short, this is not an SSRI and does not treat the same symptoms. I'm now going to try Lexapro to see if that's a better drug for me."

• Wor...
• Taken for 1 to 6 months
• July 4, 2017

For Depression "This is by far the worst medication I've tried. I got severe nausea from it every day, even after 6 weeks. It made me extremely agitated and mean and grouchy, and it raised my anxiety a ton!"

• Anonymous
• Taken for 1 to 6 months
• August 23, 2019

For Major Depressive Disorder "Great for depression, but my anxiety, which was gone when I was on Prozac, is now back and is very strong."