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Zilretta for Osteoarthritis User Reviews (Page 3)

Reviews for Zilretta

Commonly mentioned side effects
  • Ano...
  • Taken for 5 to 10 years
  • May 14, 2025

"I've been using Zilretta for 5 years or more, even before they were bought out by Pacira, and have had no problems. My injections usually last me between 3-4 months. After an injection, the pain is gone within hours. Zilretta may not work for everyone, but it works for me and I'll swear by it. I'm 67 and I'm still going to need a knee replacement, but until then it's Zilretta for the pain."

10 / 10
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  • Ter...
  • Taken for less than 1 month
  • July 6, 2022

"I have been getting steroid injections in both knees since 2010. My doctor discussed trying this drug due to my diabetes because it is supposed to not raise blood sugar numbers after the injections like other steroids do. But, leave it to me to be different, I received my injections last Thursday, and my blood sugar numbers have been on the upside of 300 since last Friday. So, I guess this medication is a no for me."

3 / 10
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  • Sus...
  • Taken for 2 to 5 years
  • June 5, 2025

"I was diagnosed several years ago with osteoarthritis in both knees. I tried multiple medications, other types of injections (including PRP), pain patches, knee braces, and physical therapy - with no lasting or significant relief. I feared I would have to stop traveling. My doctor finally prescribed Zilretta. I felt as if I never had knee pain. I could walk 10 miles a day, actually do the exercises that helped strengthen my knees, climb stairs, and stop taking the NSAIDs that not only didn’t work but caused kidney damage. Zilretta has allowed me to continue to travel, to exercise, and to avoid knee replacement. It’s been a miracle medication for me."

10 / 10
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Frequently asked questions

  • aha...
  • Taken for 1 to 6 months
  • October 26, 2024

"Works great. Took two weeks to kick in. Used for osteoarthritis, right knee. Not sure how long it will last, but it’s been almost two months. Definitely will get the injection again when it wears off. No side effects."

10 / 10
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  • BEI...
  • June 23, 2019

"I had the Zilretta injection in my knee 5 weeks ago and have been pain-free with no side effects!"

10 / 10
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26 Report

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  • Lad...
  • Taken for 1 to 6 months
  • September 26, 2019

"Lasted about a week. I am trying to put off a knee replacement. Last option was Zilretta after having 3 cortisone shots."

2 / 10
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11 Report
  • ab3...
  • Taken for 1 to 2 years
  • February 3, 2021

"I LOVE ZILRETTA!!!! It has worked wonders for me."

10 / 10
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5 Report

More FAQ

  • Bar...
  • Taken for 1 to 2 years
  • April 2, 2021

"I'm on my second year of Zilretta every four months for my left knee. Without it, I require a cane to get around. It takes a day to provide relief to my knee."

10 / 10
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3 Report
  • GiG...
  • Taken for less than 1 month
  • April 12, 2021

"My injection only lasted one month, very disappointing!"

3 / 10
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3 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.