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How is Zilretta administered?

Medically reviewed by Last updated on Oct 29, 2020.

Official Answer


Zilretta is administered as an injection into the joint.

Zilretta (triamcinolone acetonide) is Flexion’s intra-articular (injection into the joint) corticosteroid injection used for osteoarthritis (OA) knee pain.

Zilretta is a sustained-release, formulation that provides a steady concentration of drug locally to prolong the duration of OA knee pain relief for up to 12 weeks.

Zilretta is not to be considered safe for epidural (space in the spinal cord) or intrathecal (into the spinal cord area to reach the cerebrospinal fluid) administration.

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