Parnate for Depression User Reviews (Page 3)

• Gre...
• Taken for 5 to 10 years
• July 3, 2018

"Parnate is the only antidepressant worth taking."

• Dow...
• Taken for 1 to 6 months
• June 6, 2018

"Started out great, lots more energy, very upbeat. Then, at around week 3, after upping the dose to 60 mg a day, I went downhill. Couldn't get out of bed, extremely low mood, back to square 1. Had high hopes for this med, was very positive to be starting it. I'm so disappointed now."

• dan...
• Taken for 1 to 6 months
• May 25, 2018

"I have kind of atypical depression. This drug is the ONLY true antidepressant on the market. I have tried nearly all ADs, even Nardil didn't work for me. Parnate works fast and keeps working as long as you take it at the right dose and time. I can just stop and go back on this drug smoothly without side effects (maybe just some sleepiness after taking the pills). It may change your life. The only bad thing about Parnate is that it's expensive (2 bottles). Food interactions are a joke for me, I can eat whatever without a problem, but everyone is different, so follow your doctor's instructions."

• Ace...
• Taken for 1 to 2 years
• May 24, 2018

"Parnate was a miracle for me. I’d tried a few SSRIs and experienced some torturous side effects, plus having to wait six weeks every time to see if they worked... three days on 10 mg of Parnate and I felt alive again. My body buzzed and for about a day I felt ecstatic. The dietary restrictions aren’t a problem since I’m vegan, just have to curtail the avocado lust. I did recently discover that the tablets contain gelatin, however, so now I’m looking for another MAOI. It’s not the solution to all my problems, and I still need exercise, healthy eating, journaling, and time in nature to avoid feeling down/anxious, but it certainly has helped more than any of the other stuff for my mood and depression. It’s a little tricky to get it prescribed in Australia, shrinks are overly cautious about the potential interactions."

• clo...
• Taken for 10 years or more
• May 22, 2018

"Parnate is my favorite antidepressant. It took me from suicidal to happy in less than 48 hours."

• Ava...
• Taken for 2 to 5 years
• April 3, 2018

"MAOI medication is the only type of antidepressant that works for me. Both phenelzine and Parnate have been miracle drugs for me. I was on phenelzine for 24 years, and then it stopped working. I then switched to Parnate. They do not cure depression, but totally change your life so that you can function and feel happy again. No other type of antidepressant has worked for me, and I have tried a few. I have depression with anxiety, sometimes diagnosed as atypical depression also."

• cob...
• Taken for 10 years or more
• February 21, 2018

"I am asking you to go out on a limb, and trust a complete stranger, me. Parnate works for everyone. If it isn't working, you are: 1. taking the Parnate from Par Pharmaceuticals - it doesn't work long term. The Parnate you want to buy is put out by Activas Danbury, make sure the active ingredient is made in Italy - it will say on your prescription sheet. Walmart usually is willing to order it for you. 2. You are not taking enough. The therapeutic dose starts at 30mg, most people need 50 or 60mg."

• ale...
• Taken for 1 to 6 months
• November 6, 2017

"After failing to get any improvement with a whole range of antidepressants (including TCAs and Wellbutrin), I was very much looking forward to starting on Parnate. Alas, unlike other pills that had literally zero effect, this one added some negative side effects: heartaches, high blood pressure, tense feeling in the chest, and even a visit to a hospital after I fainted (luckily nothing life-threatening). I envy people whose condition improved, though. Also not sure what to do next, as this is literally the last-ditch measure, and ketamine in my country is administered only to hospital inpatients."

• Hen...
• Taken for 6 months to 1 year
• October 5, 2017

"This is one of the few drugs that actually work for me. If you're attentive, it's unlikely you'll run into trouble. If it improves life, it's worth it. We get into 2-ton things of steel and drive them around on the freeway super fast every day. Much riskier than taking Parnate. I got off for a while, and friends and family all insisted I stop trying new meds and remain on Parnate for good. No side effects. Easy to quit for a minute when dental work and surgeries come up. Sometimes it feels like the market buries the best meds for some reason. Weird."

• mai...
• September 14, 2017

"A miracle drug for my depression!!!"

• par...
• Taken for less than 1 month
• August 5, 2017

"After only a few days on Parnate, my mood declined, my sex drive totally disappeared, I lost my appetite completely, and I could only sleep 4-5 hours a night. Then my blood pressure dropped, and I wasn't able to stand much. I had heart palpitations after taking it. My mood was so dark, and my body so weak, that all I did was lie in bed for 10 days. I already have problems getting out of bed, but this made it feel impossible to move. It was absolutely miserable. I had to stop taking Parnate because it made me SO MUCH worse, and I couldn't work, eat, sleep, laugh, nothing. The reviews on here are not a balanced representation of this drug. (I have bipolar 2 depression, social anxiety, GAD, ADHD)"

• Dep...
• Taken for 1 to 6 months
• June 25, 2017

"By far the most effective med! Start at least on 30 mg a day, only side effect insomnia, but has gotten better! Been on it for 4 weeks. Combined with 40 mcg of T3 (thyroid med) as mood stabilizer. Helped so much with motivation and energy."

• Anonymous
• Taken for less than 1 month
• June 20, 2017

"I have started this and been on it for about 3 weeks. I was originally on 30 mg/day, and it has helped me so much. The only side effect I had to deal with was the upset stomach. It has helped me concentrate more on my homework, assisted me in getting a new job, and just keeping myself busy. I do hate that it only stays in effect for a couple of hours, but that's usually all I need. One thing you will have to be careful of is what you eat and how you work out. I had stopped eating chocolate and cheeses specifically due to the high tyramine level. Also, when working out, I try to take the Parnate after I am done working out, so it doesn't affect my blood pressure."

• Whi...
• May 2, 2017

"I too had tried all the tricyclics, SSRIs, and SNRIs along with helper drugs for anxiety and insomnia. I went on Parnate 4 years ago and it's the ONLY drug that has consistently worked at keeping my depression in check. After a depressive episode that almost killed me, the decision was made to try it. There is no 'poop out'. The MAOI diet everyone freaks out over is NOT that bad - just be mindful of what you eat. Following instructions for safe use of this drug is nothing compared to the relief of clinical depression!"

• Wor...
• April 1, 2017

"I have tried all the atypicals, tricyclics, SSRIs, SNRIs, and anything else they threw at me. The ONLY DRUG that helped was Parnate. The Walgreens sheet said it would kick in within 1-24 hours. After the first pill, I thought my mind had snapped. The abrupt cessation of all pain was so intense I was stunned. It has been ten years and I am still in love with this drug."

• Jma...
• January 23, 2017

"Most stable I've been in years, seem to be more in the moment, a bit more confident with people, less nervous, no feelings of depression, don't really worry so much about anything. I'm getting positive feedback from people. Not full of energy, but I'm wondering whether the emotional stability I now have will facilitate my projects. I'm more consistent, perhaps likely to get waylaid by instability. It would seem that it'd be a silly idea to go off Parnate. The food restrictions are irrelevant for me. Why would anybody who values their body and life eat pizza and cured meats? I'm feeling stronger, more clear about life - and how short it is. I take 40 mg per day."

• And...
• November 17, 2016

"No SSRI or SNRI works. Parnate works. Food restrictions caused no problems at all. Completely obliterated negative thinking and bad feeling. To me, it's a miracle drug. I was careful not to take other heavy-duty drugs at the same time. This med probably saved my life. It should be used much more frequently."

• Alm...
• Taken for 1 to 2 years
• September 21, 2016

"I have literally been on almost everything including a VNS stimulator. I had 3 near-fatal suicide attempts that put me on life support. I was even involuntarily committed to the state hospital. I have PTSD, MDD, Intermittent Explosive Disorder, and a brain injury. Parnate is the only drug that has EVER helped. All of my friends and family say there is a profound difference from just this one medication than any absurd cocktail. It even helps with my lethargy, memory impairment, and concentration. I had no problems but the reluctance of my doctor who panicked and took me off of it despite my obvious improvement. Now I got it back! It is AMAZING and tragically underutilized. Insist on it before agreeing to VNS or ECT."

• Del...
• Taken for 1 to 6 months
• September 17, 2016

"I have been taking 20 mg of Parnate every day for a little over a month now after finally convincing my psychiatrist to prescribe it. I really can't say how effective it has been in terms of alleviating the symptoms of my depression. Diet restrictions have not really bothered me at all. No real physical side effects apart from extreme sun sensitivity. This REALLY bothers me because I'm extremely fair-skinned and burn so easily - frequent, and I mean FREQUENT reapplications of sunscreen and sun avoidance are a must for me. Parnate has also decreased the effectiveness of benzodiazepines such as Valium and Imovane. This has been really frustrating because I also suffer from anxiety and insomnia."

• emg...
• September 12, 2016

"Have been on Parnate for over 20 years, use with Trazodone, and I take 40 mg Parnate, divided doses, and 250 mg Trazodone at HS. I had ECT treatments 20 years ago, but had battled major depression since high school. I do believe the Parnate has kept me on an even keel for many years. I have found with the list of everything else you cannot take with it, NutraSweet threw me into a hypertensive crisis, so heads up with that. Otherwise, I have never had any side effects with Parnate."

• A...
• Taken for 6 months to 1 year
• September 8, 2016

"Awful anxiety and depression. 25 years. Can't count the 'new and (therefore) better' SSRI drugs I tried. On Parnate, I noticed a tremendous improvement in 2 to 3 weeks. And it kept getting better! Depression and anxiety wiped away, not embarrassed to be myself anymore, social, enjoying life! Dietary restrictions are so minuscule as to be laughable. And no red wine? Chocolate? Hah! 90% of the things they tell you not to eat are bogus or unproblematic nowadays. SSRIs CAN'T RAISE SEROTONIN LEVELS anywhere near what an MAOI is capable of. And the Dopamine increase may be what has helped my energy and joy for life again. Severe and treatment resistant? Google Ken Gillman and start living."

• Hal...
• Taken for 6 months to 1 year
• August 28, 2016

"Everyone responds differently to medications, and no two people are alike - so I kind of find these forums as being useless (if not borderline ridiculous). But just to share my experience... I have MDD (treatment resistant) along with complex PTSD. I have tried every medication under the sun (over 90 different meds) before finally being introduced to Parnate in March of 2016. I was initially started at 10 mg and eventually moved up to 60 mg within 3-4 months. It seemed to be somewhat helpful for my depressive symptoms, yet it created so many other horrific side effects along with it that life is now worse than ever. Never have I been on a med with so many unwanted side effects. I'd rather be severely depressed any day of the week."

• use...
• Taken for 2 to 5 years
• July 31, 2016

"I have tried many medications for major depressive disorder, SSRIs, TCAs, as well as cognitive behavioral therapy. All of which helped to some degree, but I was never quite functioning as well as I would have hoped. Depression was ruining my life, and I was becoming very discouraged and disappointed because I had tried so many medications and other treatments, suicide was a thought I had every hour of every day. Now, every single day I am thankful I found Parnate. I get a little dizziness, some dry mouth, and some loud heartbeats, but that is an insignificant cost to pay to have the will to live back once again. If you are struggling with depression after trying many treatments, please ask your doctor about an MAOI. Best of luck!"

• Die...
• Taken for 2 to 5 years
• July 25, 2016

"The best drug for severe depression, except you cannot eat cheese or drink red wine. But try TMS, which is not a drug and has no side effects, or if necessary, ECT, which is the gold standard and is much different than in 'One Flew Over the Cuckoo's Nest.'"

• Anonymous
• Taken for 10 years or more
• June 16, 2016

"When nothing else works long term, this is the one. Pain to have to watch what you eat since it's an MAOI, but it's better than not having it!"