Tranexamic acid and Blood Clots: What Users Say

• Dol...
• Taken for 1 to 6 months
• May 13, 2021

For Heavy Menstrual Bleeding "I had a myomectomy last year in August 2020, as I had a huge fibroid, which was 15 cm. Just before this surgery, for one month, I suffered from heavy periods, and one day I had to get admitted in emergency as the flow was uncontrollable, and I was changing my pads within 5 minutes with large blood clots. To stop this bleeding, the doctor gave me an injection of tranexamic acid, and then before surgery, I had it for 2 days. It’s an effective medicine, no doubt, and after surgery, I am still taking it because of heavy bleeding on the 2nd day, but what I noticed is that it is making each cycle more heavy than the previous. Initially, I started taking only 1 pill on the 2nd day. But on the 4th month, I had to take 10 tablets for 4 days. I don’t know what this is, but tranexamic acid makes blood clots, and after taking this, I started passing more clots with less bleeding. Can anybody who has experienced the same please tell?"

• g-m...
• October 21, 2011

Tranexamic acid for Menstrual Disorders "I was diagnosed with fibroids, a tipped uterus, and a small ovarian cyst - causing extra heavy and erratic cycles. I really don't want surgery, so my GYN put me on Lysteda. I loved it for the first couple of months -- after the 2nd month, my cycle started occurring every 2-3 weeks. One month it did not happen at all. Then the last 2 cycles seemed to be normal - until the end, then they started all over again with clots and heavy bleeding. Back to my GYN. Looks like I may have to have the surgery after all."

• Tan...
• November 16, 2019

For Menstrual Disorders "I had a myomectomy about 3 years ago for fibroids. Less than a year later, in 2017, the same doctor says the fibroids came back, which means I had a pointless surgery. The doctor suggested removing my uterus at the age of 38 with no kids and apparently no future to have kids because the surgery was to enhance my chances of having kids. The doctor then suggested tranexamic acid 650 mg, 2 pills 3 times a day. The drug was working at first-lighter and shorter cycles. I was able to enjoy life during my cycles for the last 3 months (I guess there is a new manufacturer) manufacturing the drug, and now it is no longer working. Very heavy and more painful cycles. Huge blood clots and a lot more blood in the toilet, making me weak and dizzy due to the increased blood loss. I'm not sure why anyone would change the medication, but it was working great at first and now it is not. I sure hate it. My only other option is a hysterectomy while still in my late 30s. Very disappointing and disheartening."

• Deb...
• Taken for less than 1 month
• May 6, 2017

Tranexamic acid for Menstrual Disorders "Let me just say last month from the evening of the 1st to the morning of the 3rd I used 50 pads! A few tampons too! I started Lysteda on the evening of the 1st this month, yes it was lighter! 28 pads in 2 days. Day 3 and 4 got heavier! Today I had clotting like I've never seen in my 30 plus years of having a cycle (dollar bill size). The cramps were so bad I felt like I was in labor! I do suffer from fibroid tumors and anemia due to heavy bleeding. I'm having a hysterectomy next month, and my doctor wants me to take these pills again next month. I will not take any more of these pills! Not 1 more!"

• elc...
• Taken for less than 1 month
• July 29, 2019

For Menstrual Disorders "I have severe adenomyosis for more than 15 years. My uterus is as big as a 4-month-pregnant uterus would be. I am prescribed tranexamic acid because I have extremely heavy menstrual bleeding. I was on norethindrone for about 56 months, and then I received a Lupron shot (last resort) before I started tranexamic acid because somehow Lupron didn't stop my bleeding even after 4 weeks. Tranexamic acid didn't seem to work for me. I was on 6 tablets a day, and I usually take it at 8 am, 4 pm, and 11 pm (before going to bed). My bleeding would be lighter during the day, but sometime after 5 pm, I'd start seeing very heavy bleeding with blood clots. It's been going like this for a few days, and I've been to the ER twice and received a blood transfusion because I lost too much blood."

• Pip...
• Taken for less than 1 month
• March 27, 2020

For Heavy Menstrual Bleeding "Took tranexamic for one day only and developed severe side effects - numbness in the limbs, prickly skin, stabbing pains in the legs, arms, and abdomen, disturbed vision, confusion, disorientation, headache, blood clot has developed in left hand, keep getting loss of feeling in left arm. Was so severe after taking for just one day a paramedic had to be called because my husband thought I was having a stroke. Emergency GP has told me to go straight to the hospital if I don’t get better or start getting hot or swelling. Five days later still got the horrible and very scary side effects and wondering if they will ever wear off. Worst and scariest experience ever and it’s not over yet and don’t know when it will be."

• Jay...
• July 19, 2019

For Menstrual Disorders "I was bleeding heavily for almost a month, using the super pads, about 4 or 5 a day. For the first time, I went to see my doc, and she prescribed me tranexamic acid, it really did work for me. I didn't stop bleeding completely, but it went down to less than a normal flow and felt more comfortable working out and just living life. Unfortunately, the heavy bleeding has come back, and I've been prescribed more, except that my doctor said I can't be taking this every time because I may get blood clots in my legs and other places in my body. She recommended I look into getting a 'Mirena.' I've researched it, and unfortunately, you cannot become pregnant with it in you. There was no other option given. I am now wanting to see a gynecologist. I wish this would go away."

• Don...
• Taken for 1 to 2 years
• May 11, 2016

For Menstrual Disorders "I was prescribed this medicine for heavy periods by one of my doctors, but wasn't told of the potential risks until another doctor in the same clinic told me that if it's a blood-clotting medicine, it could then potentially clot your blood to cause things like stroke, etc. I was prescribed 6 tablets a day and find that taking only one makes a big difference and my periods manageable to light. The possible risk still makes me nervous, so I take as little as I can to manage my out-of-control period."

• Anonymous
• Taken for 2 to 5 years
• August 31, 2012

For Heavy Menstrual Bleeding "I've been taking this medicine for about 4 to 5 years now, and I must say, experiencing horrific periods since 11. This medicine has helped me a lot. I'm now 16, and with the help of the medicine, I can now socialize better knowing that I don't have to worry about leaking. However, I have had previous scares of blood clots, and I'm wondering if I'm at any risk while taking the dosage which I have been prescribed. Although my doctor knows of these scares, so I'm guessing that it must be safe."

• Lin...
• Taken for 1 to 6 months
• November 22, 2020

For Menstrual Disorders "I have been having a terrible time since Jan. Got my coil replaced, and it just didn’t settle my bleeding. Then in June, I had a major bleed, and the hospital said my coil had fallen out, so another one was fitted, but I haven’t stopped bleeding since June. Started injection decapeptyl to put me into menopause, along with HRT, and still bleeding heavily and with clots. So now on northerestirine 2 x 3 times a put, and on tranexamic acid, and still bleeding, and the pain is so bad. Been in and out of the hospital 7 times since June, and nobody seems to be listening. Have a scan on Monday but can’t cope with this much more, as the bleeding and pain are so bad."

• Vel...
• Taken for 2 to 5 years
• October 31, 2017

For Menstrual Disorders "I’ve had heavy periods for years, which are likely caused by fibroids. The pill and coil aren’t an option, so I was prescribed tranexamic acid, which I take sparingly on days one and two of my period. I’ve found the medication to be a great help, as it means I can go about my business without the risk of flooding and leaking through, especially at night. I currently need to wear the thickest tampon available and a long, thick nighttime towel, changing every hour on the second day. I said previously, I take it sparingly as I do wonder if the drug can cause clotting in the arteries. My GP had never really given me a definitive answer, but as a non-smoker, I would assume my risk of DVT is on the lower side."

• Chr...
• Taken for less than 1 month
• February 22, 2022

For Bleeding Disorder "We are done having kids. Over 9 years, I have tried several different IUDs and pills, but results were unsatisfactory overall. I came off the pill and took the Depo Provera shot one week ago. My primary goal was to reduce period bleeding, and I was prepared to wait through spotting. However, Depo didn't work for me. I experienced very heavy bleeding with clots. I was prescribed tranexamic acid, which has reduced the bleeding on day 1. I plan to take 2 pills daily for 8 days, and hopefully, the bleeding will stop. Otherwise, I'll keep using tranex to manage symptoms till my 3 months on Depo expire. I will not be taking another Depo shot. I'm happy to manage my periods with tranexamic acid alone. I didn't try tranexamic acid while on the pill as I was advised of the risk of increased clots. I'm so grateful to God for the invention of tranexamic acid and expect to live my life freely from here on now using it. I also considered ablation or a hysterectomy but decided neither was worth the risk!"

• Dob...
• Taken for 1 to 6 months
• April 20, 2020

Tranexamic acid for Heavy Menstrual Bleeding "I've been taking this for 2 months now, been bleeding for 18+ months ... with small changes, slightly less bleeding, but it still won't stop ... the clots are also ridiculous as well."

• Anonymous
• Taken for less than 1 month
• August 30, 2015

Tranexamic acid for Heavy Menstrual Bleeding "2 days taking 2-650 mg tablets 3x/day and no changes! Still extremely heavy bleeding and clots :("