Zepbound User Reviews & Ratings (Page 4)
Zepbound has an average rating of 8.9 out of 10 from a total of 367 reviews on Drugs.com. 84% of reviewers reported a positive experience, while 1% reported a negative experience.
Reviews for Zepbound
- BK...
- Taken for 1 to 6 months
- April 5, 2025
For Weight Loss (Obesity/Overweight) "I started this journey at 387 lbs. On the initial dosage of 2.5 mg, I lost 12 lbs in the first month. I have no side effects to speak of, and the food noise is 90% gone - although it seems to know when I'm within 24 hours of my next injection. The weight loss from the 5 mg cycle feels like another 10 lbs, but my Dr. visit will tell the tale. I am VERY happy with this decision, and I have NO regrets."
- dil...
- Taken for 1 to 6 months
- March 10, 2025
For Weight Loss (Obesity/Overweight) "I have been taking Zepbound for 4 weeks. I have lost 20 pounds. I am not hungry, no side effects, more energy, and I sleep so much better. I am on 2.5. I love this drug. I did not want to believe the good reviews or the bad ones, I just needed to know for myself, and now I do. It is great. Take a chance, you will see it really works."
Frequently asked questions
- Zepbound Vs Mounjaro: Complete Comparison Guide for Weight Loss and Diabetes Treatment
- Ozempic Side Effects to Watch For
- Why am I not losing weight on Mounjaro?
- How do Ozempic, Mounjaro, Wegovy, Zepbound compare for weight loss?
- Nan...
- Taken for less than 1 month
- January 30, 2025
For Weight Loss (Obesity/Overweight) "I have just started on the 2.5 mg dose. This is the end of my second week. I’m not experiencing any side effects except belching. I’m really looking forward to my weight loss and feel confident that with some walking daily and use of light weights I will reach my goal. I’m not overdoing the exercise, as when I do, I regrettably always quit. I’m paying for this out of pocket, so this is also a great motivator for me (get my money’s worth!) Using the injection is no problem, and I’m also looking forward to no more snoring (sleep apnea), which is a bonus as I didn’t know about that until I started taking it. This will please my husband! I’m purchasing it through Eli Lilly and my dr. sends them my script, I pay them monthly, and they send it to me via mail. I’m hoping Medicare may cover this in the future, as it’s been in the news it will if you have sleep apnea."
- Ano...
- Taken for 1 to 2 years
- June 23, 2025
For Weight Loss (Obesity/Overweight) "I have been on Zepbound for 14 months. The highest dose I reached was 12.5 mg. Have moved back down to 5 mg trying to stop since my insurance doesn’t cover it anymore. 60 years old, 5’5" and down 100 pounds."
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Your review helps others make informed decisions.- Ano...
- Taken for less than 1 month
- January 16, 2025
For Weight Loss (Obesity/Overweight) "I started 2.5 on 1/12/25. I haven't had any side effects. What I have noticed is the reduction in my need to snack. I was always wanting something after dinner. One snack turned into 2 or 3. I don't feel that way anymore. Sometimes I feel that I don't want to eat what's in front of me at mealtimes, but I am trying very hard to eat and keep protein up. I lift heavy weights 4 days a week, and I want to retain muscle if this ends up helping me finally lose the weight I've been burdened with for my entire life. I did get a bruise at the injection site. I can't wait to weigh myself to see if I've lost. So far, feeling great!"
- Kat...
- Taken for less than 1 month
- January 26, 2025
For Weight Loss (Obesity/Overweight) "I am so happy with Zepbound! I have lost 20 pounds in 3 months after 25 years of trying every diet, gimmick, supplement known to man, and nothing worked except this! My frustration and disappointment come from the insurance company that won't pay for it. I have been paying out of pocket, I get vials and do my own injections to save money. Now I need to go up in dose, and my new insurance turned me down even though I meet all the criteria. I did an appeal, and they came up with another reason to turn me down. I'm on my second appeal, and it's not looking good, so I guess I just have to blow up to 300 lbs and get diabetes and have a heart attack, which all runs in my family, before they will have to pay for it. The system is rigged! I have not had any side effects or problems with this medication."
More FAQ
- How much is Zepbound with or without insurance?
- How long does it take for Zepbound to work?
- Can you get tirzepatide from a compounding pharmacy?
- How do Zepbound and Wegovy compare?
- NJ-...
- Taken for 1 to 6 months
- January 23, 2025
For Weight Loss (Obesity/Overweight) "I've finished my 5th month of Zepbound injections. The dose pen makes the injection simple and painless. It took me a few weeks to actually feel that this was changing my appetite or cravings, but once it did, I have no problem resisting the habitual munching. Although my diet changes have helped the amount of food I eat at one time, I don't get the full feeling that a lot of people talk about. So I have to know when to push away from the servings. This was prescribed for weight loss, but I do have sleep apnea as well. I've lost 20 lbs, which matches the estimated 1 lb per week under this med. My goal weight is a 40 lb reduction. The only side effects that I've noticed are primarily increased gas and constipation if I don't push the fluids. So far, it's been a positive experience and I look forward to added results."
- jos...
- Taken for 6 months to 1 year
- May 11, 2025
For Obstructive Sleep Apnea/Hypopnea Syndrome "I started Zepbound in September 2024 to treat severe sleep apnea as diagnosed through sleep studies. I have been on the drug for 8 months and lost 35 pounds, reaching a normal weight range, and my sleep apnea is about 90-95% improved. I had mild stomach discomfort in the first month or two, but nothing very concerning. I also had some itching at the injection sites periodically over the first few months. I currently have no side effects whatsoever. I gradually ramped up from the 2.5 mg/0.5 mg dose to 5.0 mg/ml to 7.5 mg/ml, which is my final dose. This medicine was an absolute game changer. Can't emphasize how much this has improved my quality of life. I had struggled with sleep apnea and using a CPAP for about 10 years, with little success before trying this. It is important to be monitored by a doctor throughout treatment, including bloodwork, including lipase to monitor for pancreatitis."
- Ene...
- Taken for less than 1 month
- April 7, 2025
For Weight Loss (Obesity/Overweight) "Well, I am beyond the moon now that I have been approved by my insurance to take Zepbound! I have been trying to lose weight for years, practically killing myself with diets and exercise that just didn't work for my body type. I am a 59-year-young lady weighing in at 188.6 lbs. I am looking forward to my much-needed and wanted weight loss experience with Zepbound! I did my homework... Now let's go!"
- Dav...
- Taken for 1 to 6 months
- September 17, 2024
For Weight Loss (Obesity/Overweight) "I started at the beginning of May 2024 at a weight of 236. My doctor recently retired, and I was seeing his PA, and he started me on Zepbound 2.5 for a month. I had lost several pounds and moved to 5.0 mg, which I am still on, today is September 17. The PA and I agreed that this dose seems to be working well for me - today, I am 186 pounds! This medication is amazing! I have had no side effects at all."
- Tpo...
- Taken for 1 to 6 months
- March 3, 2024
For Weight Loss (Obesity/Overweight) "50-year-old female with 100 lbs to lose and PCOS. Been on Zepbound for 6 weeks (just took 7th shot). Minimal side effects. Occasional nausea, headaches, and sore muscles, usually the day after injection, but they go away by the next day. Taking the 5 mg dose right now. I have been getting large injection site rashes with itching, burning, and swelling with the last 3 doses. The swelling and itching go down after 3-4 days, but the red spots are still visible from all 3 of the previous doses. I didn't get this with the 2.5mg dose at all. Hoping it was just this last box of the medicine and the next will be better. I have only lost 5 lbs in the 6 weeks I have been on it, which has been very disappointing. It has lowered my blood pressure though. It was on the high side of normal before, now it's perfect. Really hoping that going up to the 7.5mg dose will start having better results for me as I have got a long way to go, and hopefully the skin reactions won't get worse."
- Daw...
- Taken for less than 1 month
- March 18, 2024
For Weight Loss (Obesity/Overweight) "Started Zepbound 2.5 mg just 3 days ago. For the first time in my LIFE, I am eating to nourish my body, and not to satisfy hunger or cravings! Super excited to see how the weight will drop with new habits. Downside, I wasted a pen the very first time I injected because I didn't remove the grey closure. My fault for not thoroughly following the instructions but total bummer because the cost of this med is not cheap and the pharmacy says they can't fill an Rx for just one pen. It would be nice if the manufacturer of the drug would allow a single pen to be purchased for a lesser cost."
- mis...
- Taken for 1 to 6 months
- January 23, 2025
For Weight Loss (Obesity/Overweight) "I have had a good experience with Zepbound. So far, I have lost 30 lbs in 6 months. This is my take and experience. You will feel sick if you eat improperly. You're not going to lose weight and continue to eat like you have been. Butter, fat, oil, and overeating will make you feel nauseous. These drugs slow down your digestion. I learned that in the first 24 hrs. I was at a barbecue and piled the food on my plate like normal. I felt sick the rest of the day. I learned my lesson. Make sure you drink plenty of fluids. Since digestion is slower, other functions slow down too! (If you know what I mean). Don't starve yourself, that will make you feel sick too. I have found that avoiding too many carbs and eating high in protein is working for me. I'm hoping my brain is rewired for when I go off Zepbound. I don't plan on being on this forever."
- Mer...
- Taken for 1 to 6 months
- November 5, 2024
For Weight Loss (Obesity/Overweight) "I started this medication in August 2024, and I have lost 35 lbs as of the beginning of November. I am very satisfied with this medication. I have rheumatoid arthritis, and being able to lose this weight has definitely helped my joint pain. I have tried other medications along with diet and exercise, and none have been as successful as Zepbound. I have been lucky that I have not had any side effects with this medication. I only have 15 more lbs to go. I would recommend this medication to anyone that has had trouble losing weight with other regimens."
- Gre...
- Taken for 1 to 6 months
- May 7, 2025
For Weight Loss (Obesity/Overweight) "I've been on Zepbound for 3 months. I have lost a total of 56.4 lbs. I have learned from friends I work with and other people's testimonies that use Zepbound that most people that don't lose weight don't want to try to change their eating habits, like giving up sugar. Even my doctor that's on it has struggles with this, lol. Zepbound is an awesome friend, a tool that helps with the fight, but you also have to be willing to make lifestyle changes too, and if you do, you'll see bigger results. Giving up sugar is the best thing that I have done for myself, I don't even crave it anymore and feel better than I ever have."
- And...
- Taken for 1 to 6 months
- June 8, 2024
For Weight Loss (Obesity/Overweight) "Started out great. Moved to 5.0 and had AWFUL vomiting on day 3 after injection. Dr. tried to move me back to 2.5 but Rx store was unable to get it. Went 5 weeks before it was restocked. Started 2.5 again with 0 effect. And I mean zero. Moved to 5.0 and the nausea is there, but so far, no vomiting. What concerns me is that I have suddenly been struggling with an elevated pulse and higher than normal BP. Wasn't an issue before, so not sure if it's related or incidental. May stop it because I just don't feel good. In addition over the 5 months of on and off again, I am down 4 pounds...and following a reasonable diet plan. Discouraged."
- Bor...
- Taken for 1 to 6 months
- January 17, 2025
For Weight Loss (Obesity/Overweight) "I’m almost 46. I have been struggling with weight loss all my life, joined food addiction programs, and tried other diets, and nothing worked. I lost some but gained it right back. I started at 220, but in numbers, I was not diabetic, so my insurance wouldn’t cover weight loss medication. My doctor worked with me for months and kept trying until it was finally approved. I did manage to get down to 186 pounds before starting on Zepbound. I have lost an additional 22 lb in 2.5 months! I’m at 164 now, and I haven’t been here in years. I can relate to many of the comments here. I don’t think about food, no cravings. I feel satisfied. I have been doing one meal a day, and I feel great. I don’t feel anxious, deprived, or hungry. I don’t worry about what I’m going to eat next. I don’t catch myself always snacking. It’s changed my brain in a way that I’m at peace. Just started on a 7.5 gm, and I did have some nausea just the very first day, but no other side effects."
- D R...
- Taken for 1 to 6 months
- March 14, 2025
For Weight Loss (Obesity/Overweight) "It definitely curbs your appetite, however, it destroyed my stomach. After 5 weeks, I couldn’t tolerate it anymore. I’m disappointed that my stomach and vomiting were so severe that it was not worth the risk. In a 3-week period, I had to go to the emergency room twice. I hope others have a better experience than I did."
- Anonymous
- Taken for less than 1 month
- March 27, 2025
For Weight Loss (Obesity/Overweight) "I had my first injection 4 days ago. I weighed in at 215. I have already seen a significant change in my desire to eat. I don't even consider eating until late afternoon now, while before, all I could think about was food and snacks. I work at a desk 8 hrs a day and have little opportunity to move. I also work in the medical field and have done extensive research. I am not one to try the latest trend or take medications. I had reservations about this journey, but I just felt like I needed to pop in and say I feel great with no side effects thus far, my mind feels better, and I have already lost some weight. I was educated by my Dr that I would not see immediate results, but I have!! He asked me to be patient with it, and I thought that this drug didn't sound promising. Others may not have experienced this, but I have!"
- Dia...
- Taken for less than 1 month
- June 5, 2025
For Weight Loss (Obesity/Overweight) "I have been so sick on Zepbound. Nonstop diarrhea weeks 2 and 3. Ended up in urgent care for IV hydration and labs. Doc took me off it after a severe reaction. It's been 2 weeks off it and I'm still suffering from diarrhea. Very weak and light-headed. Weight loss was fast. I started healthy and am now sick every day. Weight loss is not worth my overall health."
- MDM...
- Taken for 1 to 6 months
- December 31, 2024
For Weight Loss (Obesity/Overweight) "Started this in October of 24, went to 5.0 mg. In November, 7.5 for two weeks in December, then dropped back to 5.0 because of a few side effects, but mostly because I lost 25 lbs. in 2.5 months. That put me about where I want to be. I've stayed steady on my weight for 3 weeks now, taking 5.0 mg. every 10 days. It's great, I've had to buy new pants that fit and feel much better. Side effects weren't too bad, but you'll definitely know it if you eat too much, and over time (a couple of months) your body will slowly get used to it. I don't crave foods as I used to and only eat what I need, which is smaller amounts. I wasn't too overweight, but at 57 I suffered from high blood pressure, and age kept my weight slowly creeping up and harder and harder to keep under control. This works great!!!"
- JaM...
- Taken for 1 to 6 months
- February 17, 2025
For Weight Loss (Obesity/Overweight) "I notice I have a dry mouth when on this med, therefore, I drink more water (more water is good!). This is not serious, I just notice it. Also, I don't think I have sleep apnea, but I have snored loudly my whole life. My wife noticed I do not snore when on this med."
- Sus...
- Taken for 1 to 6 months
- October 19, 2024
For Weight Loss (Obesity/Overweight) "Been taking Zepbound 2.5 mg for four weeks - just had my fifth injection last night. Started at 254 lbs. and have lost 18 lbs!! My last weigh-in was 236 lbs.! The only annoying side effect I had was mild constipation. I had no idea what food noise was until it was gone. Wow. Finally understand what it is to be normal. Not sure what my goal weight will be yet, somewhere between 175-150 lbs. I'm in my early 50s and finally confident I'll have sustainable weight loss."
- Vio...
- Taken for less than 1 month
- May 30, 2024
For Weight Loss (Obesity/Overweight) "I started Zepbound about a week ago. Only had 1 injection, but for me personally, as soon as I did the injection, I immediately began to feel nauseated and dizzy for a good couple of hours, but then it subsided. I did have some anxiety about the side effects, and sometimes when I do have anxiety, I will feel nauseous and dizzy as well, so I really can’t tell if that was from the injection or anxiety. Either way, it stopped. Since then, I barely eat. I NEVER feel hungry at all, and when I do, I eat hardly a handful of something before I feel full and stop eating. I don’t know if that’s normal. I’m supposed to get 60 grams of protein a day. I drink 2 of those 30 grams of the Premier protein shakes, not my favorite, but it will do, and that keeps me feeling full for pretty much the ENTIRE day. I don’t snack at all anymore. Again, I’ve only had 1 injection but have noticed some immediate changes."
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For Weight Loss (Obesity/Overweight) "With the initial injection of 2.5 taken before bed. I woke up with painful, swollen neck lymph nodes and extreme fatigue. The next day, the swollen lymph nodes seemed to have moved down, now in the chest/armpit area. On the 3rd day, one of my knees is swollen and horribly painful. I have absolutely never had any knee issues prior to the injection. If I get nauseous, drinking more water helps. At this start of the med, continuing is definitely not worth it."