Zepbound User Reviews & Ratings (Page 4)
Zepbound has an average rating of 8.9 out of 10 from a total of 303 reviews on Drugs.com. 86% of reviewers reported a positive experience, while 1% reported a negative experience.
Reviews for Zepbound
- dil...
- Taken for 1 to 6 months
- March 10, 2025
For Weight Loss (Obesity/Overweight) "I have been taking Zepbound for 4 weeks. I have lost 20 pounds. I am not hungry, no side effects, more energy, and I sleep so much better. I am on 2.5. I love this drug. I did not want to believe the good reviews or the bad ones, I just needed to know for myself, and now I do. It is great. Take a chance, you will see it really works."
- Bor...
- Taken for 1 to 6 months
- January 17, 2025
For Weight Loss (Obesity/Overweight) "I’m almost 46. I have been struggling with weight loss all my life, joined food addiction programs, and tried other diets, and nothing worked. I lost some but gained it right back. I started at 220, but in numbers, I was not diabetic, so my insurance wouldn’t cover weight loss medication. My doctor worked with me for months and kept trying until it was finally approved. I did manage to get down to 186 pounds before starting on Zepbound. I have lost an additional 22 lb in 2.5 months! I’m at 164 now, and I haven’t been here in years. I can relate to many of the comments here. I don’t think about food, no cravings. I feel satisfied. I have been doing one meal a day, and I feel great. I don’t feel anxious, deprived, or hungry. I don’t worry about what I’m going to eat next. I don’t catch myself always snacking. It’s changed my brain in a way that I’m at peace. Just started on a 7.5 gm, and I did have some nausea just the very first day, but no other side effects."
Frequently asked questions
- Ozempic Side Effects to Watch For
- Zepbound Vs Mounjaro: Complete Comparison Guide for Weight Loss and Diabetes Treatment
- Why am I not losing weight on Mounjaro?
- How do Ozempic, Mounjaro, Wegovy, Zepbound compare for weight loss?
- Ano...
- Taken for less than 1 month
- April 26, 2025
For Weight Loss (Obesity/Overweight) "I am on my 5th week. Just started 5 mg Friday 04/25/25. I started 03/28/25 on the 2.5 mg. My second day I was nauseous, but nothing Sprite and Zofran couldn’t fix. Fast forward to today. I have been sleeping really well, inflammation is gone, my hunger and food noise is gone. Now I notice the day before my shot day I start to crave some, but I just drink my water to stay full. Also, a little minor constipation. I take a stool softener with my morning vitamins, which helps, plus water, water, water!! I am loving this medicine so far, I am down 10 lbs, which I don’t think that’s bad in 5 weeks."
- Bob...
- Taken for 6 months to 1 year
- February 23, 2025
For Weight Loss (Obesity/Overweight) "I’ve been taking Zepbound for 9 months and have lost approximately 25% of my original body weight, 267 lbs down to 200 lbs. I’m a 76-year-old white male with peripheral neuropathy. One noticeable side effect that I have experienced is loss of taste, which makes it hard to enjoy food. I have reached my original goal. Another benefit I have experienced is that I can sleep without using my CPAP."
Are you taking this medicine?
Your review helps others make informed decisions.- Jun...
- Taken for 6 months to 1 year
- January 26, 2025
For Weight Loss (Obesity/Overweight) "I am on the lowest dose and have been on it for several months and have lost 24 lbs. I started off slowly walking 0.5 mile a day for the first week until I was able to do 3 miles a day. I had a friend walk with me, which was a good support. The last month, I have gained 3 lbs. back because of the weather, but I am back on my grind again. So far, no real side effects. When I first started, I felt a little queasy the first 24 hours."
- NJ-...
- Taken for 1 to 6 months
- January 23, 2025
For Weight Loss (Obesity/Overweight) "I've finished my 5th month of Zepbound injections. The dose pen makes the injection simple and painless. It took me a few weeks to actually feel that this was changing my appetite or cravings, but once it did, I have no problem resisting the habitual munching. Although my diet changes have helped the amount of food I eat at one time, I don't get the full feeling that a lot of people talk about. So I have to know when to push away from the servings. This was prescribed for weight loss, but I do have sleep apnea as well. I've lost 20 lbs, which matches the estimated 1 lb per week under this med. My goal weight is a 40 lb reduction. The only side effects that I've noticed are primarily increased gas and constipation if I don't push the fluids. So far, it's been a positive experience and I look forward to added results."
More FAQ
- How much is Zepbound with or without insurance?
- Can you get tirzepatide from a compounding pharmacy?
- How long does it take for Zepbound to work?
- How do Zepbound and Wegovy compare?
- mis...
- Taken for 1 to 6 months
- January 23, 2025
For Weight Loss (Obesity/Overweight) "I have had a good experience with Zepbound. So far, I have lost 30 lbs in 6 months. This is my take and experience. You will feel sick if you eat improperly. You're not going to lose weight and continue to eat like you have been. Butter, fat, oil, and overeating will make you feel nauseous. These drugs slow down your digestion. I learned that in the first 24 hrs. I was at a barbecue and piled the food on my plate like normal. I felt sick the rest of the day. I learned my lesson. Make sure you drink plenty of fluids. Since digestion is slower, other functions slow down too! (If you know what I mean). Don't starve yourself, that will make you feel sick too. I have found that avoiding too many carbs and eating high in protein is working for me. I'm hoping my brain is rewired for when I go off Zepbound. I don't plan on being on this forever."
- Sus...
- Taken for 1 to 6 months
- October 19, 2024
For Weight Loss (Obesity/Overweight) "Been taking Zepbound 2.5 mg for four weeks - just had my fifth injection last night. Started at 254 lbs. and have lost 18 lbs!! My last weigh-in was 236 lbs.! The only annoying side effect I had was mild constipation. I had no idea what food noise was until it was gone. Wow. Finally understand what it is to be normal. Not sure what my goal weight will be yet, somewhere between 175-150 lbs. I'm in my early 50s and finally confident I'll have sustainable weight loss."
- On...
- Taken for less than 1 month
- February 18, 2025
For Weight Loss (Obesity/Overweight) "With the initial injection of 2.5 taken before bed. I woke up with painful, swollen neck lymph nodes and extreme fatigue. The next day, the swollen lymph nodes seemed to have moved down, now in the chest/armpit area. On the 3rd day, one of my knees is swollen and horribly painful. I have absolutely never had any knee issues prior to the injection. If I get nauseous, drinking more water helps. At this start of the med, continuing is definitely not worth it."
- JaM...
- Taken for 1 to 6 months
- February 17, 2025
For Weight Loss (Obesity/Overweight) "I notice I have a dry mouth when on this med, therefore, I drink more water (more water is good!). This is not serious, I just notice it. Also, I don't think I have sleep apnea, but I have snored loudly my whole life. My wife noticed I do not snore when on this med."
- Vio...
- Taken for less than 1 month
- May 30, 2024
For Weight Loss (Obesity/Overweight) "I started Zepbound about a week ago. Only had 1 injection, but for me personally, as soon as I did the injection, I immediately began to feel nauseated and dizzy for a good couple of hours, but then it subsided. I did have some anxiety about the side effects, and sometimes when I do have anxiety, I will feel nauseous and dizzy as well, so I really can’t tell if that was from the injection or anxiety. Either way, it stopped. Since then, I barely eat. I NEVER feel hungry at all, and when I do, I eat hardly a handful of something before I feel full and stop eating. I don’t know if that’s normal. I’m supposed to get 60 grams of protein a day. I drink 2 of those 30 grams of the Premier protein shakes, not my favorite, but it will do, and that keeps me feeling full for pretty much the ENTIRE day. I don’t snack at all anymore. Again, I’ve only had 1 injection but have noticed some immediate changes."
- D R...
- Taken for 1 to 6 months
- March 14, 2025
For Weight Loss (Obesity/Overweight) "It definitely curbs your appetite, however, it destroyed my stomach. After 5 weeks, I couldn’t tolerate it anymore. I’m disappointed that my stomach and vomiting were so severe that it was not worth the risk. In a 3-week period, I had to go to the emergency room twice. I hope others have a better experience than I did."
- And...
- Taken for 1 to 6 months
- June 8, 2024
For Weight Loss (Obesity/Overweight) "Started out great. Moved to 5.0 and had AWFUL vomiting on day 3 after injection. Dr. tried to move me back to 2.5 but Rx store was unable to get it. Went 5 weeks before it was restocked. Started 2.5 again with 0 effect. And I mean zero. Moved to 5.0 and the nausea is there, but so far, no vomiting. What concerns me is that I have suddenly been struggling with an elevated pulse and higher than normal BP. Wasn't an issue before, so not sure if it's related or incidental. May stop it because I just don't feel good. In addition over the 5 months of on and off again, I am down 4 pounds...and following a reasonable diet plan. Discouraged."
- Mar...
- Taken for 1 to 6 months
- May 25, 2024
For Weight Loss (Obesity/Overweight) "Started using Zepbound in March 2024, at 2.5 mg. History of Obesity (BMI > 29) and Hypertension. Starting weight was 202 lb. and Blood Pressure Avg. of 153/90. As of today, May 24, 2024, currently on 10mg. My weight is currently 177 lb, having lost 25 lbs (12%) of starting weight. It was easy to learn how to use the injection pen, and it is a painless process. I am also exercising, running 4-5 days per week and weight training 2 days per week. Exercise is an important adjunct to weight loss treatment, and can help maintain muscle mass while losing weight. It is also imperative to eat foods rich in protein and green, leafy vegetables. Side effects have been minimal, with occasional constipation, which is remedied by using Miralax or similar products."
- Rev...
- Taken for 1 to 6 months
- April 6, 2024
For Weight Loss (Obesity/Overweight) "I have been taking Zepbound for about 3 months now and have lost 18 lbs. The experience has been mostly unpleasant. The gastric issues that accompany the medication are almost unbearable. The desire to eat did not go away, and I mostly did not eat because I was always so nauseated and experiencing acid reflux. Every day has been miserable. It did make you feel good but not in a satisfied way, just full like you ate way too much to the point of feeling sick. It feels great to have lost 18 lbs, but I will probably not continue the shots due to the gastric issues."
- Ani...
- Taken for 1 to 6 months
- August 15, 2024
For Weight Loss (Obesity/Overweight) "I am 72 years old, starting weight of 210 on June 13, 2024. 1 month of 2.5 mg, then been on 5 mg. Absolutely no side effects. August 14, 2024, down to 189. Never hungry. Was concerned this was slow weight loss with reviews of 20 in one month. These reviews were reassuring to me."
- MDM...
- Taken for 1 to 6 months
- December 31, 2024
For Weight Loss (Obesity/Overweight) "Started this in October of 24, went to 5.0 mg. In November, 7.5 for two weeks in December, then dropped back to 5.0 because of a few side effects, but mostly because I lost 25 lbs. in 2.5 months. That put me about where I want to be. I've stayed steady on my weight for 3 weeks now, taking 5.0 mg. every 10 days. It's great, I've had to buy new pants that fit and feel much better. Side effects weren't too bad, but you'll definitely know it if you eat too much, and over time (a couple of months) your body will slowly get used to it. I don't crave foods as I used to and only eat what I need, which is smaller amounts. I wasn't too overweight, but at 57 I suffered from high blood pressure, and age kept my weight slowly creeping up and harder and harder to keep under control. This works great!!!"
- Fin...
- Taken for 6 months to 1 year
- September 3, 2024
For Weight Loss (Obesity/Overweight) "I started Zepbound in March of this year, along with regular exercise and a more balanced diet. Since then, I have lost 65 lbs. For the first time in over 20 years, I am under 200 lbs. I feel great. I barely use my inhaler, my knees rarely hurt, and I can jog! My labs are all within normal limits, and I feel so much better about myself. I have very little side effects from ZB: nausea the day after I take it, intolerance to most alcoholic beverages, and I get hot after every meal. I’ll take those side effects any day if it means that I’ll continue to have my life back. I’m on the highest dose now and will continue until I reach my goal of 165. I’m 5’4'' and 44 yrs old. I’m not sure that I want to get back to my high school weight of 140 or less. Anyway, I’m not here to steer anyone, I just wanted to share how well it’s going for myself."
- cli...
- Taken for 1 to 6 months
- July 31, 2024
For Weight Loss (Obesity/Overweight) "I asked my doctor about starting Wegovy since my efforts weren't working, but she recommended Zepbound - and I am so glad she did! My appetite is no longer controlling me, and yet those pre-diabetic low blood sugar drops are gone. After 3 months at the 5 mg dose, I'm still consistently losing about 1% of my weight each week. The only side effects are minor constipation and heartburn, but they encourage me to drink more water. I was hesitant to start because...needles...but it's so tiny I don't feel it at all. I wish I had started sooner!"
- Anonymous
- Taken for 1 to 6 months
- February 16, 2025
For Weight Loss (Obesity/Overweight) "My side effects are constipation, headaches, vision is foggy, insomnia, stomach pain, nervousness, dehydration, frequent urination, bumps on my labia. It is very easy to use. I have lost 14 pounds in two months. It does cut your hunger."
- Mat...
- Taken for 6 months to 1 year
- March 18, 2025
For Weight Loss (Obesity/Overweight) "Question: Why wouldn’t you use this to get a head start on a new life? I started on Monjaro for weight loss and had to switch to Zepbound after three months (insurance). I always dieted and would stall after 20 pounds. My ultimate goal was to lose enough weight to safely run again. After a year, I had lost 80 lbs and was able to start running. I just finished a half marathon, one year after starting this journey. The side effects of it are what is advertised; some nausea, it can hit you but goes away quickly, the heartburn was less with Zepbound than Monjaro, and the decrease in using the bathroom is a godsend for anyone experiencing IBS. The injection is not bad with the auto pen. Take the leap and change your life!"
- Cin...
- Taken for 1 to 6 months
- August 10, 2024
For Weight Loss (Obesity/Overweight) "I didn’t have any side effects. I lost 15 lbs in 4 months. I lost 6 inches from my waist. I went from 37 inches to 31 inches. I’m starting to tone up. I’m back to working out 4-5 days for an hour a day. I still have ways to go, but it’s looking good and I’m feeling good."
- ric...
- Taken for less than 1 month
- May 26, 2024
For Weight Loss (Obesity/Overweight) "So, I took one dose, unfortunately, my doctor screwed up and started me at 15mg. I've been in the ED for 36 hours and have had the worst 3 weeks of my life. This is not a review but a caution, check your script thoroughly, make sure you're taking the right dose. I need to purge this dose from my system and then start a 2.5mg dose."
- KCP...
- Taken for 1 to 6 months
- August 30, 2024
For Weight Loss (Obesity/Overweight) "Life-changing. Down 30 pounds in 5 months. Within a few hours of the first dose, I experienced hunger suppression, increased satiety, and best of all, reduced food noise. I thought about food 24/7 before taking this medication. Despite tracking calories and eating whole foods and eliminating most sugar, I always craved sweet and high-fat foods like ice cream and felt hungry even after a meal. On this medication, I crave veggies and fruit and protein. Side effects: as a woman going through menopause, the hot flashes have been miserable. I also have always had an extreme heat intolerance for hot weather. On this medication, hot flashes are gone and I've enjoyed summer for the first time in my life. Negative side effect: constipation. Easily manageable with Miralax and Benefiber."
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Your review helps others make informed decisions.More about Zepbound (tirzepatide)
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For Weight Loss (Obesity/Overweight) "Began 1 month ago, March 2025, starting with 2.5 mg at 210 lbs, and I am 5'4", size 14. 2nd month, same dosage, 2.5 mg. Now my weight is 183 lbs, size 10. I do have nausea, but it goes away when I drink plenty of water/seltzer. I can eat what I want, but small portions, and I can put the fork down. I take the shot at bedtime. I have only used my arms. It does not hurt. I am happy this is working."