Zepbound User Reviews & Ratings (Page 4)

• R S...
• Taken for 6 months to 1 year
• December 31, 2024

For Weight Loss (Obesity/Overweight) "I've been on Zepbound for 6 months, and it has worked great for me! 40 lbs. down!!! I only feel yucky the day after the injection, but other than that, no other concerns. I just received a letter from my insurance company (Keystone East) stating that beginning 1/1/2025, IBX in whole is no longer covering weight loss drugs. WOW!!!! :( People like myself have been waiting most of their lives for a drug like this, and here we go with corporate America. Even though I'm 40 lbs. down, I still need to lose an additional 40 lbs. just to be considered overweight and not obese in the medical world. My joints no longer hurt, and I can work out without the aches and pains. My overall health has improved so much, and I am greatly disappointed and upset with this decision from IBX. I wish everyone much luck if this will be happening to you too after the new year."

• Chr...
• Taken for 1 to 2 years
• May 11, 2025

For Weight Loss (Obesity/Overweight) "In the past year, I’ve lost 86 pounds on Zepbound—and while that alone is incredible, the real transformation goes so much deeper. I feel alive again. I’m moving more, rediscovering joy in my body, and for the first time in years, I’m not battling daily IBS symptoms. It’s not just about the weight—it’s about finally having a quality of life I never thought possible, even when I was younger and thinner. I'm truly grateful for this life-changing medication."

• She...
• Taken for 1 to 6 months
• February 10, 2025

For Weight Loss (Obesity/Overweight) "I started in October and am now on 10 mg. I have lost 106 lbs. I feel better than I have in years. I’m 69 and will be 70 in August. I do more, I get out more, I’m involved again. I have 60 more to go. I’m not saying it’s been a bed of roses, but the good outweighs the bad days 95%. Also, in the beginning, I would give myself the injection at night and then take something for nausea my doctor prescribed and no longer felt nauseous. Good luck, everyone, to a longer and better life."

• Ano...
• Taken for 1 to 6 months
• April 19, 2025

For Weight Loss (Obesity/Overweight) "Began 1 month ago, March 2025, starting with 2.5 mg at 210 lbs, and I am 5'4", size 14. 2nd month, same dosage, 2.5 mg. Now my weight is 183 lbs, size 10. I do have nausea, but it goes away when I drink plenty of water/seltzer. I can eat what I want, but small portions, and I can put the fork down. I take the shot at bedtime. I have only used my arms. It does not hurt. I am happy this is working."

• mis...
• Taken for 1 to 6 months
• January 23, 2025

For Weight Loss (Obesity/Overweight) "I have had a good experience with Zepbound. So far, I have lost 30 lbs in 6 months. This is my take and experience. You will feel sick if you eat improperly. You're not going to lose weight and continue to eat like you have been. Butter, fat, oil, and overeating will make you feel nauseous. These drugs slow down your digestion. I learned that in the first 24 hrs. I was at a barbecue and piled the food on my plate like normal. I felt sick the rest of the day. I learned my lesson. Make sure you drink plenty of fluids. Since digestion is slower, other functions slow down too! (If you know what I mean). Don't starve yourself, that will make you feel sick too. I have found that avoiding too many carbs and eating high in protein is working for me. I'm hoping my brain is rewired for when I go off Zepbound. I don't plan on being on this forever."

• jos...
• Taken for 6 months to 1 year
• May 11, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "I started Zepbound in September 2024 to treat severe sleep apnea as diagnosed through sleep studies. I have been on the drug for 8 months and lost 35 pounds, reaching a normal weight range, and my sleep apnea is about 90-95% improved. I had mild stomach discomfort in the first month or two, but nothing very concerning. I also had some itching at the injection sites periodically over the first few months. I currently have no side effects whatsoever. I gradually ramped up from the 2.5 mg/0.5 mg dose to 5.0 mg/ml to 7.5 mg/ml, which is my final dose. This medicine was an absolute game changer. Can't emphasize how much this has improved my quality of life. I had struggled with sleep apnea and using a CPAP for about 10 years, with little success before trying this. It is important to be monitored by a doctor throughout treatment, including bloodwork, including lipase to monitor for pancreatitis."

• dil...
• Taken for 1 to 6 months
• March 10, 2025

For Weight Loss (Obesity/Overweight) "I have been taking Zepbound for 4 weeks. I have lost 20 pounds. I am not hungry, no side effects, more energy, and I sleep so much better. I am on 2.5. I love this drug. I did not want to believe the good reviews or the bad ones, I just needed to know for myself, and now I do. It is great. Take a chance, you will see it really works."

• Bor...
• Taken for 1 to 6 months
• January 17, 2025

For Weight Loss (Obesity/Overweight) "I’m almost 46. I have been struggling with weight loss all my life, joined food addiction programs, and tried other diets, and nothing worked. I lost some but gained it right back. I started at 220, but in numbers, I was not diabetic, so my insurance wouldn’t cover weight loss medication. My doctor worked with me for months and kept trying until it was finally approved. I did manage to get down to 186 pounds before starting on Zepbound. I have lost an additional 22 lb in 2.5 months! I’m at 164 now, and I haven’t been here in years. I can relate to many of the comments here. I don’t think about food, no cravings. I feel satisfied. I have been doing one meal a day, and I feel great. I don’t feel anxious, deprived, or hungry. I don’t worry about what I’m going to eat next. I don’t catch myself always snacking. It’s changed my brain in a way that I’m at peace. Just started on a 7.5 gm, and I did have some nausea just the very first day, but no other side effects."

• Dav...
• Taken for 1 to 6 months
• September 17, 2024

For Weight Loss (Obesity/Overweight) "I started at the beginning of May 2024 at a weight of 236. My doctor recently retired, and I was seeing his PA, and he started me on Zepbound 2.5 for a month. I had lost several pounds and moved to 5.0 mg, which I am still on, today is September 17. The PA and I agreed that this dose seems to be working well for me - today, I am 186 pounds! This medication is amazing! I have had no side effects at all."

• Tpo...
• Taken for 1 to 6 months
• March 3, 2024

For Weight Loss (Obesity/Overweight) "50-year-old female with 100 lbs to lose and PCOS. Been on Zepbound for 6 weeks (just took 7th shot). Minimal side effects. Occasional nausea, headaches, and sore muscles, usually the day after injection, but they go away by the next day. Taking the 5 mg dose right now. I have been getting large injection site rashes with itching, burning, and swelling with the last 3 doses. The swelling and itching go down after 3-4 days, but the red spots are still visible from all 3 of the previous doses. I didn't get this with the 2.5mg dose at all. Hoping it was just this last box of the medicine and the next will be better. I have only lost 5 lbs in the 6 weeks I have been on it, which has been very disappointing. It has lowered my blood pressure though. It was on the high side of normal before, now it's perfect. Really hoping that going up to the 7.5mg dose will start having better results for me as I have got a long way to go, and hopefully the skin reactions won't get worse."

• And...
• Taken for 1 to 6 months
• June 8, 2024

For Weight Loss (Obesity/Overweight) "Started out great. Moved to 5.0 and had AWFUL vomiting on day 3 after injection. Dr. tried to move me back to 2.5 but Rx store was unable to get it. Went 5 weeks before it was restocked. Started 2.5 again with 0 effect. And I mean zero. Moved to 5.0 and the nausea is there, but so far, no vomiting. What concerns me is that I have suddenly been struggling with an elevated pulse and higher than normal BP. Wasn't an issue before, so not sure if it's related or incidental. May stop it because I just don't feel good. In addition over the 5 months of on and off again, I am down 4 pounds...and following a reasonable diet plan. Discouraged."

• Vio...
• Taken for less than 1 month
• May 30, 2024

For Weight Loss (Obesity/Overweight) "I started Zepbound about a week ago. Only had 1 injection, but for me personally, as soon as I did the injection, I immediately began to feel nauseated and dizzy for a good couple of hours, but then it subsided. I did have some anxiety about the side effects, and sometimes when I do have anxiety, I will feel nauseous and dizzy as well, so I really can’t tell if that was from the injection or anxiety. Either way, it stopped. Since then, I barely eat. I NEVER feel hungry at all, and when I do, I eat hardly a handful of something before I feel full and stop eating. I don’t know if that’s normal. I’m supposed to get 60 grams of protein a day. I drink 2 of those 30 grams of the Premier protein shakes, not my favorite, but it will do, and that keeps me feeling full for pretty much the ENTIRE day. I don’t snack at all anymore. Again, I’ve only had 1 injection but have noticed some immediate changes."

• Daw...
• Taken for less than 1 month
• March 18, 2024

For Weight Loss (Obesity/Overweight) "Started Zepbound 2.5 mg just 3 days ago. For the first time in my LIFE, I am eating to nourish my body, and not to satisfy hunger or cravings! Super excited to see how the weight will drop with new habits. Downside, I wasted a pen the very first time I injected because I didn't remove the grey closure. My fault for not thoroughly following the instructions but total bummer because the cost of this med is not cheap and the pharmacy says they can't fill an Rx for just one pen. It would be nice if the manufacturer of the drug would allow a single pen to be purchased for a lesser cost."

• yan...
• Taken for less than 1 month
• April 4, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "I take my second 2.5 mg Zepbound tomorrow. I am so impressed so far with this med. I am in my 60s and have tried dieting with initial success and then rebound. I swim and use an elliptical, which makes me feel good but has not helped me lose weight. This is a different experience. Like others say, it turns off the craving 'noise', you feel full all the time, and food is no longer the enemy. I have been eating fruits and veggies, chicken, beef, and eggs. Cottage cheese tastes great for the first time and is a great small meal. I drink water with sliced lemons, which tastes great and is satisfying. I have never been much of a water drinker, but now that is all I want other than tea and coffee. I have probably lost about 2 lbs so far as my always bloated belly is flattening, though I have a long way to go. I have had a few mild headaches and vomited on night three, otherwise, no side effects. I'm all in!"

• JoD...
• Taken for less than 1 month
• September 7, 2025

For Weight Loss (Obesity/Overweight) "I started Zepbound with the expected side effects, chills, extreme fatigue, nausea, massive potty dumps. I am now down with days of horrible abdominal intestinal pain. I cannot go to the bathroom! I have stopped this med."

• Ano...
• Taken for 1 to 6 months
• August 15, 2025

For Weight Loss (Obesity/Overweight) "I was on Wegovy for a few months starting last year. I had GI issues going on and ended up getting off Wegovy in January of this year. I had gallbladder removal surgery in March. Issues went away. I consulted with my GI doctor to see if I could get back on Wegovy. He said I should be fine. Went to my PCP and asked about getting back on Wegovy. She recommended Zepbound as “side effects are less.” I’ve been on Zepbound for 3 months now. Lowest dose. After the second day of injection, I get the worst sulfur burps and diarrhea. Once I have a sulfur burp, the diarrhea is inevitable. It’s gotten to the point where it wakes me up in the middle of the night and I have to use the bathroom. This just started happening within the last month. It usually lasts about a day. Never had these issues with Wegovy. In fact, Wegovy worked much quicker with me as far as losing weight. Didn’t have these burps and diarrhea when I took it for months."

• Nan...
• Taken for less than 1 month
• January 30, 2025

For Weight Loss (Obesity/Overweight) "I have just started on the 2.5 mg dose. This is the end of my second week. I’m not experiencing any side effects except belching. I’m really looking forward to my weight loss and feel confident that with some walking daily and use of light weights I will reach my goal. I’m not overdoing the exercise, as when I do, I regrettably always quit. I’m paying for this out of pocket, so this is also a great motivator for me (get my money’s worth!) Using the injection is no problem, and I’m also looking forward to no more snoring (sleep apnea), which is a bonus as I didn’t know about that until I started taking it. This will please my husband! I’m purchasing it through Eli Lilly and my dr. sends them my script, I pay them monthly, and they send it to me via mail. I’m hoping Medicare may cover this in the future, as it’s been in the news it will if you have sleep apnea."

• Mer...
• Taken for 1 to 6 months
• November 5, 2024

For Weight Loss (Obesity/Overweight) "I started this medication in August 2024, and I have lost 35 lbs as of the beginning of November. I am very satisfied with this medication. I have rheumatoid arthritis, and being able to lose this weight has definitely helped my joint pain. I have tried other medications along with diet and exercise, and none have been as successful as Zepbound. I have been lucky that I have not had any side effects with this medication. I only have 15 more lbs to go. I would recommend this medication to anyone that has had trouble losing weight with other regimens."

• NJ-...
• Taken for 1 to 6 months
• January 23, 2025

For Weight Loss (Obesity/Overweight) "I've finished my 5th month of Zepbound injections. The dose pen makes the injection simple and painless. It took me a few weeks to actually feel that this was changing my appetite or cravings, but once it did, I have no problem resisting the habitual munching. Although my diet changes have helped the amount of food I eat at one time, I don't get the full feeling that a lot of people talk about. So I have to know when to push away from the servings. This was prescribed for weight loss, but I do have sleep apnea as well. I've lost 20 lbs, which matches the estimated 1 lb per week under this med. My goal weight is a 40 lb reduction. The only side effects that I've noticed are primarily increased gas and constipation if I don't push the fluids. So far, it's been a positive experience and I look forward to added results."

• BK...
• Taken for 1 to 6 months
• April 5, 2025

For Weight Loss (Obesity/Overweight) "I started this journey at 387 lbs. On the initial dosage of 2.5 mg, I lost 12 lbs in the first month. I have no side effects to speak of, and the food noise is 90% gone - although it seems to know when I'm within 24 hours of my next injection. The weight loss from the 5 mg cycle feels like another 10 lbs, but my Dr. visit will tell the tale. I am VERY happy with this decision, and I have NO regrets."

• Jus...
• Taken for less than 1 month
• December 28, 2024

For Weight Loss (Obesity/Overweight) "After my second 2.5 shot, the side effect symptoms are too much for me to handle. I’ve barely kept any food down except for a day and a half before my second shot. I can’t find a way to prevent acute nausea, and the vomiting is now making me weak. I knew there would be side effects, but for me, this medication doesn’t work for my body. I chose to discontinue the medication and will work with my doctor to see what other options may work for me. I have been unable to participate in family and home life, feeling trapped between being so sick I can’t leave my bed and spending a lot of time vomiting or feeling like I will if I try to move or drink water. I hoped this would be the tool to help me on a healthier path, and it’s not the right one for me, but I can see how it would possibly help others if they aren’t affected by side effects."

• Ano...
• Taken for less than 1 month
• January 16, 2025

For Weight Loss (Obesity/Overweight) "I started 2.5 on 1/12/25. I haven't had any side effects. What I have noticed is the reduction in my need to snack. I was always wanting something after dinner. One snack turned into 2 or 3. I don't feel that way anymore. Sometimes I feel that I don't want to eat what's in front of me at mealtimes, but I am trying very hard to eat and keep protein up. I lift heavy weights 4 days a week, and I want to retain muscle if this ends up helping me finally lose the weight I've been burdened with for my entire life. I did get a bruise at the injection site. I can't wait to weigh myself to see if I've lost. So far, feeling great!"

• Ano...
• Taken for 1 to 6 months
• June 11, 2025

For Weight Loss (Obesity/Overweight) "As soon as I began at the 2.5 dosage, I modified my diet radically to mitigate or even entirely avoid the dreaded side effects of indigestion, nausea, constipation, heartburn, and vomiting. I also embarked on a free-weight program to build muscle. Fortunately, I’ve experienced none of the unpleasant side effects. I’ve titrated up after each 4-week dosage and am now in the middle of 7.5 mg. My doctor tells me I have lost more weight than most patients have at this point. I also have chronic inflammation, which extra weight exacerbates, and I’m watching carefully to see that marker decrease. That’s the good news. Zepbound has completely changed my relationship to food. I consider myself a “foodie.” That’s now behind me. I remind myself that it’s been only 10 weeks. I’m hopeful that at some point, I will be able to enjoy more of the foods that were once such a large part of my life."

• D R...
• Taken for 1 to 6 months
• March 14, 2025

For Weight Loss (Obesity/Overweight) "It definitely curbs your appetite, however, it destroyed my stomach. After 5 weeks, I couldn’t tolerate it anymore. I’m disappointed that my stomach and vomiting were so severe that it was not worth the risk. In a 3-week period, I had to go to the emergency room twice. I hope others have a better experience than I did."

• Nan...
• Taken for 1 to 6 months
• July 26, 2025

For Weight Loss (Obesity/Overweight) "I have had great success with Zepbound! I am down almost 40 pounds in 3 months. I started at 201 lbs. I have been lucky not to have any issues or side effects. I do work at it. I drink lots of water and walk 20 minutes twice a day."