Zepbound User Reviews & Ratings (Page 3)

• Tit...
• Taken for less than 1 month
• January 22, 2025

For Obstructive Sleep Apnea/Hypopnea Syndrome "Second week, as of yesterday, no side effects other than not sleeping well the first couple of nights after injecting. I’ve lost close to 5 lbs in the first week. I’ve been reading that if you experience insomnia it is because of the rapid weight loss and to try and change the time of injection. I did it at 6 PM both last Tuesday and yesterday, next Tuesday I’m doing it in the morning. The key for me if not having the side effects that many people experience is that I have been eating clean before starting the medication and continue to eat clean as well as having a high-protein meal 45 minutes to an hour prior to injection. We’ll see how it goes next week when I inject in the morning instead of the evening."

• Anonymous
• Taken for less than 1 month
• March 24, 2024

For Weight Loss (Obesity/Overweight) "Ten days on Zepbound. Love this medication. The energy it gives you is amazing. 1st day injection in thigh developed bruise and slight nausea and headache. But no biggie. 2nd shot belly super easy. Takes away urge to eat. No more stomach grumbling when hungry either. I have a protein shake in the morning, mid-morning protein bar, little bites throughout the morning. Small lunch and salmon or chicken for dinner. Veggies and fruit are important. No issue with bathroom. I take a fiber gummy and multivitamin daily. Treadmill and gym. After showering, I've been using lots of lotion on skin, massaging in. You'll be fine. Smart choices in foods. Yogurt gave me nausea as did tuna with mayonnaise. 6 lbs so far."

• Kat...
• Taken for 1 to 2 years
• June 8, 2025

For Weight Loss (Obesity/Overweight) "I have used this for over 1 1/2 years now. I have never increased from the initial 2.5 dose and have lost over 45 lbs! 63 yrs old and always fought my weight. I could literally fast for a couple of days, stay on my tuna, veggies, and berries the rest of the week, exercise every day and gain 2 lbs if my week was stressful at work. This turns on a couple of hormones that just were not working no matter what I tried. I have no plans to increase this dose, but will probably need to stay on this forever. It is the key and the answer I’ve been looking for. Most every post I’m reading talks about increasing the dose, and I wanted to share that you can get there without risking additional side effects. It’s a great tool, and with all the good things we do already for ourselves, this will take you all the way! I’m about 12 pounds to my goal, now normal cholesterol levels and no side effects after the first two weeks :). It makes the journey easier when you see success for your efforts :)"

• bae...
• Taken for 1 to 6 months
• March 18, 2024

For Weight Loss (Obesity/Overweight) "Absolutely life-changing. For the first time in my life, I'm satisfied by reasonable portions. I'm not always thinking about the next thing that I'll be eating. I'm able to feel and respond to my actual hunger cues without my scarcity brain taking over. Even if I wasn't losing weight, the relief of food obsession and binge eating disorder would be worth it. Four weeks in, down 13 lbs and very satisfied. Only side effect has been feeling cold and some mild constipation."

• mje...
• Taken for 1 to 6 months
• May 9, 2024

For Weight Loss (Obesity/Overweight) "I originally started the Zepbound shot at the end of this past January. I weighed a total of 202 lbs when I started it. That would be about 3-4 months ago. I was very self-conscious, I didn't want to take any pictures of myself, I felt disgusted by myself, I always brought myself down, etc. But now, now I weigh 154 lbs. I'm at the 10 mg of the Zepbound. I started off as the lowest and I'm still not at the highest, to be honest. I lost about 50 pounds in the last 4 months! I researched it and it'll take 16 months to lose about 50 pounds for a normal person who doesn't take anything. And I did it in 4 months with that shot! I never thought I would get to this weight, to be honest. In the beginning, I was going to the YMCA to work out every week to put in the extra work, etc. At first, I started losing like a pound a day, not even kidding, sometimes 2 lbs a day. Then it went to a pound every couple days, and it would vary."

• Mik...
• Taken for 1 to 6 months
• January 15, 2024

For Weight Loss (Obesity/Overweight) "I’m a 6’4", 275-pound male, 62 years old - no diabetes or health issues, on no other meds. Obtained prescription via Dr. and took the first 2.5 mg injection on Dec. 24. Lost 10 pounds with the first 3 shots, then Dr. said I could go to 5 mg (saved the last 2.5 mg pen for future use) because weight loss had stopped. After starting 5 mg, lost 2 pounds in 2 days - so combined weight loss using 2.5/5 mg is now at 12 pounds in six weeks! No significant or terrible side effects except some constipation, intermittent fatigue, and minor chills at times (not a lot - could just be the cold weather). I've yo-yoed up and down with weight for years. Because of my size, I can eat a lot of food - but this drug has significantly reduced my appetite, and I have more energy overall. I can’t wait to see the results in a few more months. Zepbound has so far been perfect for me. I don’t mind the $550 price (with the Lilly savings card - has been hard to get CVS to make it work, but that’s another story/nightmare)."

• Sus...
• Taken for 1 to 6 months
• June 24, 2024

For Weight Loss (Obesity/Overweight) "I’ve used Zepbound for almost 5 months & have lost 15 lbs. I experienced diarrhea at the beginning but much less now. What I didn’t expect was that my bladder issues like leaking, etc. would stop. It has been amazing! I went from needing valve & bladder surgeries to complete stoppage. I hope this info will help other women with their urology issues. Even if I never lost another pound, if another Zepbound side effect helps my bladder, I’m in!!"

• ali...
• Taken for 1 to 6 months
• April 29, 2024

For Weight Loss (Obesity/Overweight) "Started at the end of Jan 24. 4 weeks at 2.5mg, 8 weeks at 5mg due to lack of supply. I've had to seek alternatives due to the shortage of this drug, but it is worth it. I've lost 30 pounds in 14 weeks and moved up to 7.5mg on my last dose. The food noise is gone. The alcohol noise is gone. Other than some nausea and fatigue on shot day, side effects have been mild and easily manageable. I wish I'd have been able to start this long ago and gotten my life back. 30 pounds to go and I have no doubt I will be successful."

• Chr...
• Taken for 1 to 2 years
• May 11, 2025

For Weight Loss (Obesity/Overweight) "In the past year, I’ve lost 86 pounds on Zepbound—and while that alone is incredible, the real transformation goes so much deeper. I feel alive again. I’m moving more, rediscovering joy in my body, and for the first time in years, I’m not battling daily IBS symptoms. It’s not just about the weight—it’s about finally having a quality of life I never thought possible, even when I was younger and thinner. I'm truly grateful for this life-changing medication."

• Kgr...
• Taken for less than 1 month
• January 22, 2025

"I am 45, 5’5 currently weighing 187 lbs. I wanted to share my weight-loss journey thus far as well as share my progress moving forward. I started a 1,200-calorie or less diet and 45 min exercise plan in Sept 2024 weighing in at 192 lbs with consultation from my PCP. With the weight loss of 5 lbs I’ve started feeling very defeated. Along with being obese, I was diagnosed with OSA in 2018. Now the FDA has approved Zepbound for the treatment of sleep apnea (OSA), and I decided to take advantage of that decision. I spoke with my GP, she shared my office consultation notes with my sleep doctor. My sleep doctor thought Zepbound would be of great benefit to me since I have been on a calorie deficit diet and consistent exercise routine over 3 months with less than 5% weight loss. My insurance agreed and approved Zepbound with a copay of $60. With the Zep savings card, I paid $25. I will provide you all with an update in 4 weeks."

• Dee...
• Taken for 1 to 6 months
• April 6, 2025

For Weight Loss (Obesity/Overweight) "I started in January and have moved doses up monthly. This morning I took my 4th 7.5 mg dose. I did have a 2.5 mg pen malfunction and moved up to 5 a week early. I've been losing 1-3 pounds a week, for a total today of 28 lb loss. My goal is to lose 50. As far as side effects, they really aren't too bad for me. Daily Colace helps any constipation, which has not been much of an issue anyway. Occasional nausea is fleeting and is helped with Coke One. I know some are against drinking soda, but Coke One does not have sugar and has been my nausea cure for as long as it's been on the market. My appetite is diminished, but not gone. I've changed my eating pattern to several small, healthy mini-meals during the day instead of 3 'regular' meals. Zero cravings for junk food or much snacking at all. Part, I'm sure, is that I'm keeping those mini meals full of protein and vegetables. The only real issue that I've had is fatigue. It hits about an hour after the shot and lasts about 36 h."

• Anonymous
• Taken for 1 to 6 months
• February 26, 2024

For Weight Loss (Obesity/Overweight) "So far, so good. Rarely get hungry and can't eat too much. Side effects: Heartburn, reflux, constipation, hair loss. I will have to weigh myself in the morning, but I am guessing I am down about 8 lbs. in 5 weeks. Just started on the 5 ml. No exercise yet. Wine and alcohol will definitely slow down the progress. Not a lot of cravings for junk. Every now and then I want something fried, but it will have you on the crapper by the next morning! Stay away from greasy food on this! And YES, the needle DOES hurt to me!"

• foo...
• Taken for 1 to 6 months
• July 22, 2024

For Weight Loss (Obesity/Overweight) "I've been on this medication for 6 weeks and have never felt better about my body or my day. I didn't realize I could have a day where I wasn't thinking about food from the minute I got up until I fell asleep at night. I feel free to think about other things and to not be distracted by trying to have willpower to not eat. It's a huge relief. Is this what thin people feel like? People who have never struggled with being overweight? I have always thought my weight was based on my genetics, and maybe it is-but it's also my brain that literally is addicted to food. It feels like I've been released from an addiction. I haven't noticed any side effects. I tried Ozempic before this and was very constipated and had stomach issues. I don't feel that way at all on Zepbound, my stomach is fine. I'm on 2.5, it's very easy to administer, and I feel like it really works. I hope I'm able to take it for a long time, I'm sort of afraid to go back to the brain I had before taking it."

• Can...
• Taken for 1 to 6 months
• April 18, 2024

For Weight Loss (Obesity/Overweight) "I am in my 50s and I stayed on the 2.5 for 2 months and just began the 5 mg today. I had gastric sleeve exactly a year before covid, lucky me, huh? Working from home, no gym, already had depression, joint, and severe back issues. It all did not mix with slowing down and sitting down. I gained half of the weight I lost, and the high cholesterol returned. I started Zepbound on Feb 17, 2024, and lost 18 lbs by my first check-up on April 1. Very fast. My cholesterol dropped significantly. I do not have high blood pressure, but it was down too. All blood work is great. The only side effect is constipation that I fixed with Miralax. There are no food cravings or noise in my head. I get full very fast, although I have to remind myself to eat. I have dry mouth, I bought sugar-free popsicles to deal with that. I have been sleeping better, although I stay up late due to the energy it gives me."

• Lin...
• Taken for 1 to 6 months
• December 5, 2024

For Weight Loss (Obesity/Overweight) "I started taking Zepbound on the first of September, am 5'8, was weighing 190. I stopped taking Zepbound on November 18th, had no serious side effects, I was just feeling moody. Stopped at my goal of 175.9 and still losing on my own. It's December 5, and I weigh 172.9. Zepbound has taught me to eat a balanced, healthy meal without all the cravings, portion size, and exercise. Down 16 pounds."

• CJa...
• Taken for 1 to 6 months
• April 1, 2025

For Weight Loss (Obesity/Overweight) "I started 3 months ago with the 2 ml, then 5, and now 7.5. I have been nauseous every single day for those 3 months. I have been constipated almost every week. I finally am able to go. I noticed that after the injection, I vomit every time the next day. I am 5'7 and weighed 233. I am now 209. The nausea is sometimes unbearable. I feel like not taking this medicine. Everyone's body is different."

• Ano...
• Taken for 1 to 6 months
• April 19, 2025

For Weight Loss (Obesity/Overweight) "Began 1 month ago, March 2025, starting with 2.5 mg at 210 lbs, and I am 5'4", size 14. 2nd month, same dosage, 2.5 mg. Now my weight is 183 lbs, size 10. I do have nausea, but it goes away when I drink plenty of water/seltzer. I can eat what I want, but small portions, and I can put the fork down. I take the shot at bedtime. I have only used my arms. It does not hurt. I am happy this is working."

• R S...
• Taken for 6 months to 1 year
• December 31, 2024

For Weight Loss (Obesity/Overweight) "I've been on Zepbound for 6 months, and it has worked great for me! 40 lbs. down!!! I only feel yucky the day after the injection, but other than that, no other concerns. I just received a letter from my insurance company (Keystone East) stating that beginning 1/1/2025, IBX in whole is no longer covering weight loss drugs. WOW!!!! :( People like myself have been waiting most of their lives for a drug like this, and here we go with corporate America. Even though I'm 40 lbs. down, I still need to lose an additional 40 lbs. just to be considered overweight and not obese in the medical world. My joints no longer hurt, and I can work out without the aches and pains. My overall health has improved so much, and I am greatly disappointed and upset with this decision from IBX. I wish everyone much luck if this will be happening to you too after the new year."

• Ano...
• Taken for 1 to 6 months
• May 14, 2025

For Weight Loss (Obesity/Overweight) "I started on Friday, March 21, and had no side effects for the first two weeks. Then I overate cheesy pasta and had severe diarrhea. The next 10 days, I had three more episodes of diarrhea and vomiting. And severe fatigue. I was not able to continue my exercise routine as often as usual. The fatigue after minimal activity was interfering with my life. I cannot walk more than a few blocks. I stopped the injections three weeks ago, and for the most part, I have intermittent fatigue. It apparently takes about 25 days for the med to be out of the system. I lost 9 pounds after the first 3 or 4 weeks and have not gained them back. I didn't have quite the same separation of thoughts of food as I had expected. Hopefully, only another week or two to get my energy back."

• 64...
• Taken for 1 to 6 months
• May 19, 2025

For Weight Loss (Obesity/Overweight) "Just took shot #5 of 2.5g this morning. In the last month I've lost 8#. The head thing other people talk about is real: on Zepbound, I don't crave junk foods, only desire normal portions, food-obsessing is gone, and it does not change how food tastes. Hallelujah! 1st thing: eat a lot of protein, at least 80g/day and this will help to ensure you burn fat rather than muscle. 2nd thing: drink at least 80 oz of water/day to keep side effects away."

• Mil...
• Taken for 6 months to 1 year
• December 1, 2024

For Weight Loss (Obesity/Overweight) "I started Zepbound in April 2024 at 193 lbs. It’s December 2024, I’m now 140 lbs. I have stayed at the 10 mg dose for almost 3 months now, as I am trying to tone my body since I lost 50 lbs fast. The side effects suck when I go up a dose, but my body adjusts after 4 weeks, so it’s been great. I have noticed that I wake up with hunger pains now, but my plan is to get used to them again before I start weaning off the drug. Side effects for me include headaches and fatigue. It’s not that bad after a while, the main thing is being strategic and proactive about getting your fiber, protein, and water in. I haven’t been to the gym since I started the 10 mg, and I’ve slowed down on the weight loss (which I’m okay with). I like 140, I’m just trying to tone now, so when I wean off, it won’t all come back. I’ll update you guys in a couple of months."

• She...
• Taken for 1 to 6 months
• February 10, 2025

For Weight Loss (Obesity/Overweight) "I started in October and am now on 10 mg. I have lost 106 lbs. I feel better than I have in years. I’m 69 and will be 70 in August. I do more, I get out more, I’m involved again. I have 60 more to go. I’m not saying it’s been a bed of roses, but the good outweighs the bad days 95%. Also, in the beginning, I would give myself the injection at night and then take something for nausea my doctor prescribed and no longer felt nauseous. Good luck, everyone, to a longer and better life."

• JWa...
• Taken for 1 to 6 months
• March 28, 2025

For Weight Loss (Obesity/Overweight) "Zepbound was effective within the first week. I experienced a significant decrease in hunger and decreased interest in food. I also found that I could not always finish a meal serving in one sitting. Initially, I had minor issues in bowel habits (constipation and diarrhea). Both symptoms are minor and managed with adequate hydration and fiber-rich foods. More disconcerting have been the “egg burps” caused by bacterial action on sulfur-rich foods in a slowed GI system. I have selected less sulfur-rich foods and make a concerted effort to drink more water during a day or two following the weekly injection. This side effect seems to have moderated, perhaps as I am into the second month of my current dosage and third month on Zepbound and/or temporarily minimizing sulfurous food intake in a short period following injection. I also track my food intake and assure I am eating an adequate level of protein. I have lost 15 pounds in 10 weeks. I am 77 and a woman."

• Ill...
• Taken for 1 to 6 months
• February 14, 2024

For Weight Loss (Obesity/Overweight) "I have been on Zepbound for 6 weeks. (4 weeks 2.5) (2 weeks at 5.0) I have lost 23 lbs. 307-284 I ride bike/treadmill and lift weights. I eat 2300 calories a day. If I happen to eat too much, I don't seem to notice. But what I do notice is I don't crave food like before. Before, I used to still be hungry after dinner. Not anymore. That part of my brain that was ravenous for more is gone."

• she...
• Taken for 1 to 6 months
• March 18, 2024

For Weight Loss (Obesity/Overweight) "I have been on Zepbound for two months and have lost only 9 pounds. I don't eat breakfast because I am not hungry, this has been a lifelong habit of mine. I am hungry at noon and eat more than I should. I have found that I am eating too fast, which is causing me to not have the weight loss that I would have if I ate slower. I have noticed that when I eat slower, I stop eating when I am halfway done with my meal. Hopefully, I can break a lifelong habit of eating fast. I have no side effects from the drug or overeating."