Tirzepatide User Reviews & Ratings (Page 5)
Brand names: Mounjaro, Zepbound
Tirzepatide has an average rating of 8.6 out of 10 from a total of 2,013 reviews on Drugs.com. 80% of reviewers reported a positive experience, while 5% reported a negative experience.
Reviews for Tirzepatide
- bae...
- Taken for 1 to 6 months
- March 18, 2024
For Weight Loss (Obesity/Overweight) "Absolutely life-changing. For the first time in my life, I'm satisfied by reasonable portions. I'm not always thinking about the next thing that I'll be eating. I'm able to feel and respond to my actual hunger cues without my scarcity brain taking over. Even if I wasn't losing weight, the relief of food obsession and binge eating disorder would be worth it. Four weeks in, down 13 lbs and very satisfied. Only side effect has been feeling cold and some mild constipation."
- Chr...
- Taken for less than 1 month
- June 29, 2022
"Started with 2.5, been on it nearly three weeks, anticipated side effects but other than mild constipation, I experienced none. My appetite was nonexistent, had to remember to eat. Night eating gone, overeating gone, strong cravings gone. Injection easy peasy. Coupon only way I could afford this med (25/mo versus over 1k/mo). No feeling weird like stimulants, just pretty normal. I'm pairing with intermittent fasting per my GP and trying to incorporate intuitive eating as much as possible. I am not counting calories or weighing myself but I am likely down 5-10# in 2 weeks combo of water weight and loss. Bloat gone, body feels good, excited to see if this keeps working this well."
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Wegovy
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Mounjaro
Mounjaro is used for type 2 diabetes to help lower blood sugar levels. Mounjaro has also been shown ...
Zepbound
Zepbound (tirzepatide) is an FDA-approved weekly injection for weight loss and obstructive sleep ...
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Tresiba
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Frequently asked questions
- Zepbound Vs Mounjaro: Complete Comparison Guide for Weight Loss and Diabetes Treatment
- Why am I not losing weight on Mounjaro?
- How do Ozempic, Mounjaro, Wegovy, Zepbound compare for weight loss?
- Tirzepatide vs semaglutide: How do they compare?
- mje...
- Taken for 1 to 6 months
- May 9, 2024
For Weight Loss (Obesity/Overweight) "I originally started the Zepbound shot at the end of this past January. I weighed a total of 202 lbs when I started it. That would be about 3-4 months ago. I was very self-conscious, I didn't want to take any pictures of myself, I felt disgusted by myself, I always brought myself down, etc. But now, now I weigh 154 lbs. I'm at the 10 mg of the Zepbound. I started off as the lowest and I'm still not at the highest, to be honest. I lost about 50 pounds in the last 4 months! I researched it and it'll take 16 months to lose about 50 pounds for a normal person who doesn't take anything. And I did it in 4 months with that shot! I never thought I would get to this weight, to be honest. In the beginning, I was going to the YMCA to work out every week to put in the extra work, etc. At first, I started losing like a pound a day, not even kidding, sometimes 2 lbs a day. Then it went to a pound every couple days, and it would vary."
- Mik...
- Taken for 1 to 6 months
- January 15, 2024
For Weight Loss (Obesity/Overweight) "I’m a 6’4", 275-pound male, 62 years old - no diabetes or health issues, on no other meds. Obtained prescription via Dr. and took the first 2.5 mg injection on Dec. 24. Lost 10 pounds with the first 3 shots, then Dr. said I could go to 5 mg (saved the last 2.5 mg pen for future use) because weight loss had stopped. After starting 5 mg, lost 2 pounds in 2 days - so combined weight loss using 2.5/5 mg is now at 12 pounds in six weeks! No significant or terrible side effects except some constipation, intermittent fatigue, and minor chills at times (not a lot - could just be the cold weather). I've yo-yoed up and down with weight for years. Because of my size, I can eat a lot of food - but this drug has significantly reduced my appetite, and I have more energy overall. I can’t wait to see the results in a few more months. Zepbound has so far been perfect for me. I don’t mind the $550 price (with the Lilly savings card - has been hard to get CVS to make it work, but that’s another story/nightmare)."
Are you taking this medicine?
Your review helps others make informed decisions.- Car...
- Taken for 1 to 6 months
- October 21, 2022
For Type 2 Diabetes "I am 6ft and started at 213lbs. Blood sugars were a little elevated and I could see they were headed in the wrong direction. I also have severe sleep apnea. I started at 7.5 and just finished my fourth week. This drug is amazing. I’m down 24 lbs in 28 days. Lost 4 lbs last week. Current weight is 189lb. Goal is 175lb. I check my blood sugar 2 or 3 times a day. My highest reading was 101 about an hour after eating. Most readings in the low 80s which is perfect. I couldn’t have asked for more from this drug. Side effects are constipation (drink lots of water) and tired the day after the shot. I’ve been slightly overweight my entire life. I hope to lose this weight and then see if the sleep apnea goes away. Life changing."
- Dia...
- Taken for 6 months to 1 year
- November 8, 2024
For Weight Loss (Obesity/Overweight) "When I started out on the lowest dosage, everything went great. I have lost 40 pounds and have been pleased. I requested from my doctor to up my dosage to 5 mg. Now I have an allergic reaction, mostly on my face. Red, splotchy, hot marks all over my face. Have there been any other patients that have experienced the same reaction?"
More FAQ
- How much is Zepbound with or without insurance?
- Mounjaro side effects you need to be aware of
- How does Mounjaro Work for Weight Loss?
- Can you get tirzepatide from a compounding pharmacy?
- Sus...
- Taken for 1 to 6 months
- June 24, 2024
For Weight Loss (Obesity/Overweight) "I’ve used Zepbound for almost 5 months & have lost 15 lbs. I experienced diarrhea at the beginning but much less now. What I didn’t expect was that my bladder issues like leaking, etc. would stop. It has been amazing! I went from needing valve & bladder surgeries to complete stoppage. I hope this info will help other women with their urology issues. Even if I never lost another pound, if another Zepbound side effect helps my bladder, I’m in!!"
- Dia...
- Taken for less than 1 month
- June 5, 2025
For Weight Loss (Obesity/Overweight) "I have been so sick on Zepbound. Nonstop diarrhea weeks 2 and 3. Ended up in urgent care for IV hydration and labs. Doc took me off it after a severe reaction. It's been 2 weeks off it and I'm still suffering from diarrhea. Very weak and light-headed. Weight loss was fast. I started healthy and am now sick every day. Weight loss is not worth my overall health."
- Pen...
- Taken for less than 1 month
- September 23, 2022
For Type 2 Diabetes "I started taking Mounjaro on 9/1. This resulted in the very worst month of my life. WEEK ONE - Super Nauseous, indigestion, stomach pain for 3-4 days of the first week. My appetite went from a 10 to a 2 (which was good). WEEK TWO - I had diarrhea for 3-4 days, along with sulfur belches, nausea, stomach pain. I ended up having to take sick days and go get an IV bag to recover from the dehydration. WEEK THREE - World-class nausea and vomiting. 3 days of vomiting so hard that I ruptured my esophagus. The entire month, if I was not having diarrhea, I was VERY constipated. I lost 9 lbs in one month, but I don't know if it was because I could barely eat due to the sickness. PASS!!"
- Kgr...
- Taken for less than 1 month
- January 22, 2025
"I am 45, 5’5 currently weighing 187 lbs. I wanted to share my weight-loss journey thus far as well as share my progress moving forward. I started a 1,200-calorie or less diet and 45 min exercise plan in Sept 2024 weighing in at 192 lbs with consultation from my PCP. With the weight loss of 5 lbs I’ve started feeling very defeated. Along with being obese, I was diagnosed with OSA in 2018. Now the FDA has approved Zepbound for the treatment of sleep apnea (OSA), and I decided to take advantage of that decision. I spoke with my GP, she shared my office consultation notes with my sleep doctor. My sleep doctor thought Zepbound would be of great benefit to me since I have been on a calorie deficit diet and consistent exercise routine over 3 months with less than 5% weight loss. My insurance agreed and approved Zepbound with a copay of $60. With the Zep savings card, I paid $25. I will provide you all with an update in 4 weeks."
- ali...
- Taken for 1 to 6 months
- April 29, 2024
For Weight Loss (Obesity/Overweight) "Started at the end of Jan 24. 4 weeks at 2.5mg, 8 weeks at 5mg due to lack of supply. I've had to seek alternatives due to the shortage of this drug, but it is worth it. I've lost 30 pounds in 14 weeks and moved up to 7.5mg on my last dose. The food noise is gone. The alcohol noise is gone. Other than some nausea and fatigue on shot day, side effects have been mild and easily manageable. I wish I'd have been able to start this long ago and gotten my life back. 30 pounds to go and I have no doubt I will be successful."
- Gav...
- Taken for 1 to 2 years
- February 4, 2024
For Type 2 Diabetes "I am a 6'2", 46-year-old male who started his journey at 305 lbs. My doctor prescribed me Mounjaro 10.0 in Jan. of 2023. In Dec. of 2023, I went to level 12.5. Mounjaro, along with a balanced diet and exercising 4-5 days a week, changed my life for the better. I went from a 'Living to Eat' person to an 'Eating to Live' person. Mounjaro helps me mentally and physically. After I eat, I feel fuller longer, and I don't get food cravings. It's amazing!! I went from 305 lbs to 238 lbs. That is 67 lbs in 13-14 months. I am off all insulin. I stopped snoring at night. I am participating in 5K races. Achieving goals and having fun! Team Gavin, I treat my body like a football team - Offense - gym four to five days a week, Defense - portion control, Special Teams - Mounjaro injections once a week. I don't think I could be doing this well without all three. The journey continues for me, and I hope after you read this, it begins with you. Good luck!"
- Tee...
- Taken for 1 to 6 months
- October 13, 2022
For Type 2 Diabetes "I have been on 2.5 mg for 5 weeks. My starting weight was 263. I have lost 15 lbs. with no side effects. My doctor has placed me on the 5 mg dosage. Hopefully I will continue losing weight with no side effects."
- Ano...
- Taken for less than 1 month
- June 9, 2025
For Weight Loss (Obesity/Overweight) "I’m starting the initial dose, which is 2.5 mg weekly, and I haven’t felt any side effects. I already had my third injection. I feel less hungry, which is good because I’m an emotional eater. I’ve already lost 10 lbs. The injection is really very simple to use."
- Amb...
- Taken for 1 to 6 months
- April 27, 2023
For Weight Loss (Obesity/Overweight) "I was on Mounjaro for 3 months for weight loss, starting weight 180 lbs. I increased to the next dosage every month. I had minimal side effects besides constipation and lost a total of 28 lbs. I did not wing off the medication, and everything went fine. I did blood work last week, and everything was perfect compared to the year before. My weight has been steady thanks to the healthy habits I built during the medication."
- Anonymous
- Taken for 1 to 6 months
- March 29, 2023
For Weight Loss (Obesity/Overweight) "I'm on month three. My doctor thinks I might be too sensitive to it and may have to stop soon. Extreme nausea, occasional vomiting, and sulfur burps followed by diarrhea, weakness, and lethargy. The pros: in three months, I've gone from 262 lbs to 239 lbs."
- Dee...
- Taken for 1 to 6 months
- April 6, 2025
For Weight Loss (Obesity/Overweight) "I started in January and have moved doses up monthly. This morning I took my 4th 7.5 mg dose. I did have a 2.5 mg pen malfunction and moved up to 5 a week early. I've been losing 1-3 pounds a week, for a total today of 28 lb loss. My goal is to lose 50. As far as side effects, they really aren't too bad for me. Daily Colace helps any constipation, which has not been much of an issue anyway. Occasional nausea is fleeting and is helped with Coke One. I know some are against drinking soda, but Coke One does not have sugar and has been my nausea cure for as long as it's been on the market. My appetite is diminished, but not gone. I've changed my eating pattern to several small, healthy mini-meals during the day instead of 3 'regular' meals. Zero cravings for junk food or much snacking at all. Part, I'm sure, is that I'm keeping those mini meals full of protein and vegetables. The only real issue that I've had is fatigue. It hits about an hour after the shot and lasts about 36 h."
- Mim...
- Taken for 1 to 6 months
- December 29, 2022
For Type 2 Diabetes "I'm type 2 diabetic and was on Ozempic for quite some time and having difficulty getting my medication. My doctor changed me to Mounjaro for my diabetes thinking I would be able to get my meds. I started on the 5 mg since I had been on Ozempic. My side effects were typical slight nausea. I was trying to get my second month filled and the issues started with availability AGAIN. The 5 mg and 7.5 mg were on backorder. He increased my dose to 10 mg. I have experienced sulfur burps, but that is about it. I have not seen much weight loss, but then again I'm more concerned about my diabetes. Shame on the drug companies for dangling a medication that works to lower A1C and cholesterol and choosing to utilize it for weight loss where the insurance won't cover it. I'm not using this medication for vanity, it's for my chronic disease."
- Ano...
- Taken for 1 to 6 months
- April 19, 2025
For Weight Loss (Obesity/Overweight) "Began 1 month ago, March 2025, starting with 2.5 mg at 210 lbs, and I am 5'4", size 14. 2nd month, same dosage, 2.5 mg. Now my weight is 183 lbs, size 10. I do have nausea, but it goes away when I drink plenty of water/seltzer. I can eat what I want, but small portions, and I can put the fork down. I take the shot at bedtime. I have only used my arms. It does not hurt. I am happy this is working."
- Bla...
- Taken for 1 to 6 months
- April 2, 2025
For Weight Loss (Obesity/Overweight) "I have been struggling with my weight since I was 16. I quit smoking, had two children, entered menopause, and my weight became uncontrollable (my blood tests have always been perfect). I found the strength to start dieting a couple of times a year but hit rock bottom in March, 48 years old, 107 kgs. Depressed and unable to start -again- the keto diet (it works very well for me), I asked for help and was put on antidepressants and Mounjaro. A real game changer. I started the diet with no willpower, no bad feelings, no cravings, no need for self-control, just naturally. I got into ketosis easily and quickly. As a side effect, I have slight nausea a couple of days after the injection. No big deal, as it helps with the diet. No more food noise, I am able to think and prepare my meals without rushing, and so far, I have lost 6 kg in 14 days. I plan to continue for as long as I can and then stop and get my weight under control. We'll see."
- Lil...
- Taken for less than 1 month
- March 26, 2023
For Weight Loss (Obesity/Overweight) "I have been on Mounjaro for just two weeks. I've lost 5 pounds without trying. While that's nice, I am posting a very early review to let other newbies know that other than some indigestion the first two days, I haven't had any side effects. I had major constipation on Ozempic. I find taking a daily stool softener, staying hydrated, taking a Metamucil tablet daily, and taking a daily prebiotic (get the refrigerated one in your pharmacy as it has live cultures. Keep it refrigerated!). I'm on 5 mg, but I am moving up to 7.5 next week. I will go to 10 mg if there is no supply of 7.5. My pharmacist said to get my order for the 7.5 mg in at least 7 days early so they can get it in on time. They don't stock it, but they get it overnight. Just FYI, after using Ozempic and Mounjaro, I weigh less than I did 10 years ago. I've gone down 4 sizes and 4 inches off my waist since Christmas! Now a petite XL rapidly headed to petite L."
- CJa...
- Taken for 1 to 6 months
- April 1, 2025
For Weight Loss (Obesity/Overweight) "I started 3 months ago with the 2 ml, then 5, and now 7.5. I have been nauseous every single day for those 3 months. I have been constipated almost every week. I finally am able to go. I noticed that after the injection, I vomit every time the next day. I am 5'7 and weighed 233. I am now 209. The nausea is sometimes unbearable. I feel like not taking this medicine. Everyone's body is different."
- Geo...
- Taken for 1 to 6 months
- June 8, 2025
For Weight Loss (Obesity/Overweight) "Started Zepbound in late December of 2024, I weighed 257 lbs. As of June 6th, 2025, I weigh 214 lbs. It has helped me curb my appetite, pay more attention to my calories with hardly any side effects. Very happy with the results and I am almost at my target weight."
- Anonymous
- Taken for 1 to 6 months
- February 26, 2024
For Weight Loss (Obesity/Overweight) "So far, so good. Rarely get hungry and can't eat too much. Side effects: Heartburn, reflux, constipation, hair loss. I will have to weigh myself in the morning, but I am guessing I am down about 8 lbs. in 5 weeks. Just started on the 5 ml. No exercise yet. Wine and alcohol will definitely slow down the progress. Not a lot of cravings for junk. Every now and then I want something fried, but it will have you on the crapper by the next morning! Stay away from greasy food on this! And YES, the needle DOES hurt to me!"
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Your review helps others make informed decisions.More about tirzepatide
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For Weight Loss (Obesity/Overweight) "Ten days on Zepbound. Love this medication. The energy it gives you is amazing. 1st day injection in thigh developed bruise and slight nausea and headache. But no biggie. 2nd shot belly super easy. Takes away urge to eat. No more stomach grumbling when hungry either. I have a protein shake in the morning, mid-morning protein bar, little bites throughout the morning. Small lunch and salmon or chicken for dinner. Veggies and fruit are important. No issue with bathroom. I take a fiber gummy and multivitamin daily. Treadmill and gym. After showering, I've been using lots of lotion on skin, massaging in. You'll be fine. Smart choices in foods. Yogurt gave me nausea as did tuna with mayonnaise. 6 lbs so far."