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Sertraline User Reviews & Ratings (Page 4)

Brand names: Zoloft

Sertraline has an average rating of 7.3 out of 10 from a total of 4,563 reviews on Drugs.com. 64% of reviewers reported a positive experience, while 18% reported a negative experience.

Reviews for Sertraline

Commonly mentioned side effects
  • Hea...
  • Taken for 1 to 2 years
  • April 28, 2016

Sertraline for Social Anxiety Disorder "33 y/o female, 5'5, 125 lbs, 200 mg/day, 1 1/2 years and will continue indefinitely. Pros: social anxiety gone. Unbelievable. Able to start spontaneous conversations with 'strangers', now able to develop and share deep, intimate friendships. Not hyper self-conscious anymore. I joke around and enjoy making people laugh. Sexually uninhibited (with my husband) - seriously, the best sex I've ever had, I'm not self-conscious at all anymore and I have no problems with orgasm - actually the opposite (best. ever.) Weight loss, 25-30 lbs, and I feel light, energetic and happy with my body now. Food! I used to be a horribly picky eater my entire life, now I try new foods without a second thought and enjoy them! Zoloft has changed my life."

9 / 10
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  • Yay...
  • December 12, 2014

For Anxiety and Stress "Long story short, anxiety took over my life overnight. I was experiencing looping thoughts, negative anxiety-causing ones. I am big on organic food/natural remedies, etc. I don't even like cold medicine, so I went three months battling daily attacks. Finally, I couldn't take it anymore. The doctor prescribed clonazepam and sertraline. It did take the full five weeks for me, but I gained control of my thoughts right away, within days! Amazing! I lost weight on this, but my appetite has now returned. I feel great! Totally normal, eight weeks in, and forgot I ever had anxiety in the first place. I feel 100% normal. I wish I would have gone to the doctor sooner. Hang in there, you can beat this!"

10 / 10
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  • meg...
  • Taken for 1 to 6 months
  • January 10, 2021

For Generalized Anxiety Disorder "I suffer from anxiety and derealization. This medication is a lifesaver. I rated it a 9 because the side effects are horrific. If you are just starting off, please give it time. It took me 8 weeks to start to feel normal again. I would read all the reviews trying to find an answer, but instead I put myself down reading the negative ones. Be patient and be kind to yourself. It is hard, and you do feel like it's never going to get better. I promise it will, hang in there. I was in such a dark place, but there is light at the end of the tunnel. Don't expect to feel better overnight, it is such a gradual thing, and it will take time, but you will get there!! One thing I would say is don't bottle it up, if you are having a bad day, speak to someone. Don't let it feel like you are going backwards because everyone has bad days."

9 / 10
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Frequently asked questions

  • Zim...
  • Taken for 6 months to 1 year
  • November 20, 2019

For Anxiety and Stress "When you start sertraline, you need to stick with it. It doesn't start working for 6 weeks. I've had anxiety all my life but 3 years ago developed OCD and panic disorder. The first 2 weeks of taking sertraline was awful. Horrible thoughts, racing heart, anxiety worrying if the pill would work, then there was a sick feeling, dodgy tummy, etc. You only feel rubbish for 2-3 weeks and then you feel just as you would before the pill. Anyway, I read on the NHS website that Sertraline takes 4 weeks to start working for depression and 6 weeks for anxiety. And true to word, I started feeling great after 6 weeks. I was patient and it paid off. I've been on it for almost 12 months and it's the best decision I've made. I don't care if I have to take this for life, if I feel better mentally, then surely my body will be healthier physically!"

10 / 10
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  • Joe...
  • Taken for less than 1 month
  • March 31, 2015

For Obsessive Compulsive Disorder "I thought I was too far gone. I have Pure O - every second of every single day was torture. I didn't want to live anymore, I couldn't with the obsessive thoughts that were so antithetical to who I was. Constantly, I would tell myself who I was, but the OCD would always trick me out of my logic. OCD has your whole imagination at its disposal. I got a lot worse before I got better on Sertraline. REMEMBER WHO YOU ARE AND STICK IT OUT. One day, you'll feel like you've been punched and woken up from a bad dream. If I can do it when I was on the verge of suicide, you can too. I believe in you."

10 / 10
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  • red...
  • Taken for 1 to 6 months
  • June 3, 2021

Sertraline for Social Anxiety Disorder "When I say Zoloft changed my life, I mean Zoloft not only changed but SAVED my life. It is the quickest acting medication for anxiety I have ever been on, along with being the one with the least side effects. I was having such awful anxiety that it was crippling me and making it unbearable to live. I started taking Zoloft (50mg) and that worked for me but I still had an anxiety attack here and there, upped to 75mg and it has completely changed my life for the better. My body feels calm and at peace."

10 / 10
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  • sor...
  • Taken for 1 to 6 months
  • May 2, 2020

For Anxiety and Stress "My son worried constantly about having cancer. He had these thoughts for over 2 years. I hated to see him like this. Always crying, frightened. He smoked, so it made the health anxiety much worse. He was put on sertraline. He was very ill for 4 weeks, much worse than before he started taking it. But now he doesn't talk about it and is now happier. I can't believe it. How it's changed my 26-year-old son's life. He still has autism, he always will, but he is so much happier, and the anxieties have 90 percent gone. Thank you, sertraline. You are a magic pill. Mother of Luke."

9 / 10
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More FAQ

  • The...
  • October 29, 2014

For Generalized Anxiety Disorder "Just a few weeks ago I was reading all these reviews in tears. I am a 36-year-old mother of two & suddenly I started having panic attacks. I was so scared to start taking Zoloft because I thought it would 'change' me or make me feel 'off.' This was SO not the case! I tried everything natural I could first, but I was still having anxiety regularly. I was also having negative thoughts that I could not stop, I would have to actively try not to think about certain things, and I really struggled with that. I have been on Zoloft for about 2 weeks and all of that has stopped! I feel happy! I didn't even realize I had been in a funk, I feel so so SO much better now. To anyone reading this, you're not alone, it can and will get better!"

10 / 10
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  • Joe...
  • Taken for 1 to 6 months
  • May 9, 2015

For Anxiety and Stress "This has been one of the toughest medications I have ever been on. I've been on countless numbers of antipsychotics, antidepressants, mood stabilizers... Around 25 medications in total. I was wrongly diagnosed as borderline personality and suffered greatly as a result. Sertraline made everything so much worse for about three weeks, but then, it was like a switch had been pressed in my head. My racing, obsessive thoughts stopped, my constant headaches, insomnia, sweating, worrying, heart pains, vanished. I can think, I can feel, and I can, for the first time in a long time, be 100% completely myself without the pain. You don't get points in this world for suffering, and this has improved my life by about 100000000%. Stick with it."

10 / 10
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  • Anonymous
  • October 3, 2018

Sertraline for Major Depressive Disorder "I suffer from major depression & several cases of depression from having unresolved grief. Zoloft helped me a lot. Before I got on medicine, I was fighting demons & having death thoughts & a lot of thoughts that weren’t normal. Depression is real. If you don’t get help, you could end up committing suicide or living a life that is not healthy. Ultimately, this medication Zoloft helped me. Depression is a disease that never goes away - you have to live & fight through it every day for the rest of your life & confront it. Never give up. Someone loves you & needs you to keep fighting. It's not just your battle, it's all of ours!"

10 / 10
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  • Anonymous
  • Taken for 2 to 5 years
  • April 19, 2013

Sertraline for Depression "I have been on Zoloft 100mg for the last 3 years. It has been a lifesaver for me. Before Zoloft, everyone kept telling me I was depressed and experiencing anxiety. I didn't believe them. I thought that was just me. Then, at my doctor's strong recommendation, I started with the Zoloft. It did make me tired at first, but I continued to take it and am so glad I did. I no longer have crying spells or lay in bed not wanting to get up. I no longer freak out (as my kids would say) or obsess about small things that really didn't matter. I no longer have a short fuse. I am calm, relaxed, nice, and very happy. I cannot imagine my life without Zoloft. Zoloft has made me a much better mom and person."

9 / 10
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  • Jay...
  • Taken for 1 to 6 months
  • August 21, 2020

For Anxiety and Stress "I’m on week 5 of sertraline 50mg and I think I’ve had every side effect which has been horrendous - but most disappeared after 2 weeks. I still have dreadful morning anxiety, a cough that comes and goes and ringing in my ear but all manageable. That’s the negative part. On a positive note, I haven’t had a panic attack since starting this medication and my mood swings are loads better. I hear myself laugh more. I’m keeping everything crossed that I will see more improvement with the anxiety. I have never suffered from anything like this until 7 months ago, and I refused medication thinking it will pass (it doesn’t). If you can get past the first few weeks, you will start seeing positive changes. I still have a few bad days, but nothing like it was without the medication. Good luck to all starting."

9 / 10
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  • Ann...
  • Taken for 1 to 6 months
  • October 2, 2016

Sertraline for Depression "My doctor prescribed this for depression issues/severe anxiety associated with adult ADD. I was very resistant to try, have been put on multiple other meds that made things much worse. I take 50mg daily. Immediately felt almost 'euphoric.' With each passing day, I feel better in every sense, and the anxiety is gone. I NEVER write any posts EVER, but this has been an unbelievable game changer. I have been battling these issues since childhood, and I can truly say I feel happy and hopeful about my future. The 'internal storm' inside that I battled every day to cope with is gone. No side effects except for some vivid, strange dreams but those are dissipating. I hope this helps someone-if this one doesn't help, keep trying and never give up."

10 / 10
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  • Suz...
  • Taken for 1 to 6 months
  • October 18, 2023

For Anxiety and Stress "For anyone struggling with the first few days/weeks/months, please stick with Sertraline. I was where you are now and I used to read all the reviews and pray that it worked for me. It did! I was no longer having racing heart, negative thoughts, and an absolutely crushing feeling of anxiety in my stomach every morning when I woke up, it just all went away! At the beginning, I couldn't even get out of bed, and now I am back at work, enjoying my family, my beautiful grandchildren. I started on 50mg and now take 100mg daily. Please stick with it, and I hope it works for you!"

10 / 10
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  • JPh...
  • Taken for 1 to 6 months
  • July 4, 2023

Sertraline for Post Traumatic Stress Disorder "About 8 months ago, I began a battle with post-traumatic stress and major depressive disorder. Traumas from years past that I had never faced resurfaced and turned my life upside down. I wasn't sleeping or eating. At one point, I went nearly forty hours without sleep and was considering taking my own life. I suffered terrible panic attacks and had nonstop intrusive thoughts. This went on for months until I started on Zoloft about 13 weeks ago at 50 mg. I noticed a minor improvement over the next 5 weeks. At 100 mg, I noticed much more progress over the next five weeks. Presently, I am at 150 mg and have noticed a major difference. What I found is that Zoloft slows the intrusive thoughts and allows me to access the things I work on in therapy and actually apply them, whereas before, the emotions were too much. This medication takes time to work. I read these reviews during my hardest times, and it really helped me stay positive. Stay strong. Keep working. It gets better. I promise."

10 / 10
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  • Mar...
  • Taken for 1 to 2 years
  • July 19, 2023

For Generalized Anxiety Disorder "I started suffering from anxiety in my teens. I am now 54 and managed to have a good life and hold down a good job. But when I got into my 50s, it became really difficult to deal with and I was forced to seek help about 18 months ago. My doctor prescribed me 50mg of sertraline. I was in a right mess and struggling to function. But after about 6 weeks, I went out for a meal with my wife and realized I had felt slightly better and my mind was a bit quieter. And that was the first glimmer of hope. I went back to the doctor and he increased it to 100mg. And the better days increased. I would say I was 75%. Then the doctor asked me if I wanted to try 150mg. I did and this is where I am now, and I would say I am 90% and I am really enjoying life. I would sit on the edge of my bed every night reading these reviews and tried to get some hope and promised myself that when I was better, I would leave a review to give others hope. Don't give up, take the medication and try to stay busy. Sertraline works!"

10 / 10
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  • Jen...
  • Taken for 1 to 6 months
  • October 3, 2021

Sertraline for Panic Disorder "I promised myself after reading so many reviews that I’d come back and leave one myself, but I’ve been doing so good I almost forgot. I was so nervous about starting this drug. Last January my anxiety had gotten absolutely debilitating; I was having panic attacks nearly every day. I truly couldn’t imagine ever feeling good again. And I was so scared to start taking this. I started and stopped maybe 3 times before sticking with it. I’m so glad I did. If you’re reading this, and you’re nervous about starting, and you’ve been scouring reviews online to try and convince yourself, consider this your sign! Life is tough but it doesn’t have to be. Good luck out there friends ❤️"

10 / 10
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  • Lan...
  • Taken for 1 to 6 months
  • July 10, 2021

For Anxiety and Stress "4 weeks ago I switched to sertraline 50mg as my other medication stopped working. I was on Lexapro for 6 years which changed my life! I found sertraline has really helped with my anxiety and depression, and I'm finding my daily living as a busy mom of 3, a caregiver for my husband, and a dog mom a lot more enjoyable. I am increasing today to 100mg of sertraline as this increase is needed to suit me. I found the first 2 weeks starting sertraline heightened my anxiety and depression, which Xanax helped ease the heightened anxiety for the first 2 weeks, but I held on and I am glad I did. I hope this helps someone else."

10 / 10
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  • Emi...
  • Taken for less than 1 month
  • April 29, 2021

Sertraline for Obsessive Compulsive Disorder "I was just recently diagnosed with obsessive-compulsive disorder a few months ago. I developed a strange form of OCD in which I engage in mental compulsions and have to repeat the same words in my head to relieve anxiety. A little after a week and I’m already noticing SUCH an improvement in symptoms. I don’t feel so overly aware of everything, and the best part is that I can focus at school! I was studying for an exam yesterday, and I could digest every word without my thoughts screaming at me or distracting me. It really feels as if a switch went off in my brain. My thoughts are so much more positive. This medicine has given me my life back."

9 / 10
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  • Anx...
  • July 10, 2013

Sertraline for Depression "I've been taking Zoloft for 8 years. It has created stability in my life. Prior to taking medication, I always felt off...anxious, depressed, emotional, dwelling on things, and this interfered with the quality of my life as well as affected my relationships and professional life. I take 50mg and I feel even-keeled and normal instead of a basket case of emotion. Nobody would ever know I'm taking a medication, and I'm often complimented on my temperament. I feel neutral, in control of my feelings, and everything is within normal range. If you are overly emotional, anxious, feel off-balance, and have difficulty feeling consistent in your life...this could help. I feel content and normal now."

9 / 10
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  • Hea...
  • Taken for 1 to 6 months
  • November 12, 2020

For Anxiety and Stress "I started 25mg sertraline at the end of June 2020. I was depressed as well as anxious. I used to feel like life was pointless as we all die anyway, and although I wasn’t suicidal, I didn’t want to continue living this way. The first few days I had an upset stomach and was waking up at random times through the night, but this quickly went away. I increased my dose to 50mg, which I am on now. My main side effects are vivid dreams and lack of sex drive. I still experience anxiety every so often, but it’s much better and easier to get over. I am considering increasing my dosage to 100mg to see if it helps with this. I am far less on edge and jumpy, I feel like I used to be on constant high alert, and that’s definitely reduced. My depression, I would say, is completely gone. I feel happy again and excited for the future, which I thought was impossible. I no longer think that life is pointless. I wouldn’t have thought that medication could help with these thoughts, but it definitely has."

9 / 10
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  • Mad...
  • Taken for 1 to 6 months
  • July 12, 2021

For Generalized Anxiety Disorder "I am on 50mg of sertraline. It did take a long time for the medicine to fully level out. I experienced some of the initial side effects: increased anxiety, insomnia, headaches, shakiness, jaw pain, and dizziness. But all eventually went away after a month or so of use. My husband noticed a difference in me around week 4, but I didn’t really notice much of a change until week 6/7. Honestly, I wasn’t even sure the medicine was truly working until about 12 weeks in. I have had a lot of ups and downs, but the downs have been less often since about week 4. Now at a little over 14 weeks, I feel like things have really leveled out for me. I still feel emotions. I cry, I laugh, I joke around, I get excited for family outings. All of the normal feelings are back. I don’t feel emotionally blunted. The side effects can be tough in the beginning… and from my experience, the doors and windows don’t start to open very quickly. But once they do, it can feel really incredible."

10 / 10
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  • Sla...
  • Taken for 1 to 2 years
  • December 21, 2020

Sertraline for Social Anxiety Disorder "Some of the reasons people complain about Zoloft/sertraline and say it doesn't work? Three reasons: - They didn't increase dosage when it wasn't working. - They took it for too short a time. - They got prescribed a drug that doesn't fit them or their illness. I suffered from social anxiety disorder since childhood, and for me, Zoloft started working after more than 1 month, and after a triple increase in dosage compared to the beginning. When did I know it had started working? It was like a switch, from day to day. I just had this feeling that now I don't have this 'everyone is watching and judging me.' I still have it sometimes, and that's why I'm in psychotherapy (which is also very helpful), but Zoloft changed my life, maybe not totally, but it definitely helps. But PLEASE GIVE IT SOME TIME. If something doesn't work for 2 weeks, DON'T GIVE UP and increase the dosage. If the drug doesn't work then, increase the dose again. If it doesn't work after 2 months, just ask your doctor for another drug. Keep trying and DON'T GIVE UP."

9 / 10
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  • Smi...
  • Taken for less than 1 month
  • August 23, 2020

Sertraline for Depression "Surprisingly, positive effects from Zoloft started the next morning after taking my first 25mg dose at dinner the night before. I felt so good, I thought this is what normal is. I haven't felt this good in I don't know how long. My doctor offered counseling in addition to the Zoloft, but it works so well, I don't think I need it."

9 / 10
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202 Report
  • Ano...
  • Taken for 1 to 6 months
  • November 3, 2019

Sertraline for Social Anxiety Disorder "On Zoloft for Generalized Anxiety Disorder. The first few weeks were honestly so bad. I had such bad brain fog, more anxiety, depression, wanted to sleep all the time, etc. I couldn’t eat and lost about 7 pounds within a few weeks. Things were not looking good but I pushed through it. One morning I woke up and my life had been changed. I found out what it was like to feel like everything would be okay. I am so happy I take this medicine and I recommend it for anxiety if you’re willing to push through the beginning. I have a new view on life and it feels so good."

9 / 10
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