Semaglutide and Vomiting: What Users Say (Page 2)

• Dan...
• Taken for 1 to 6 months
• February 8, 2022

For Cardiovascular Risk Reduction "I've been on Ozempic for two and a half months now for weight loss, and the results have been great. I've lost about 25 lbs. The only thing I don't really like is I truly do have no appetite. At all. So sometimes eating is a slog. Just getting through 3 or 4 bites of a meal can be annoying. And even though it's been almost 3 months, I still get nausea from time to time. I also had to dial back a lot of my social drinking, as I'm eating so little, there's nothing to absorb the alcohol in my stomach most days, causing indigestion, acid reflux, vomiting, and other problems. Still, I'm going to stick with the medication to see how much weight I can potentially lose over the course of six months."

• Abe...
• Taken for 1 to 6 months
• November 15, 2021

For Weight Loss (Obesity/Overweight) "Started out with .25 mg. I did that for four weeks and only felt slight nausea after the injection. Today, I bumped up to the .50 mg dose, and within five hours I was nauseous. I finally vomited, and I feel better, but have no appetite now. Nothing sounds good. I’m also sleepy. So far, the weight loss is only about five pounds. If I stay nauseated, it’ll probably increase drastically, but what a dumb way to live! I hope it’s temporary. I could be sick once a week and survive if I get decent weight loss. I am also fairly active, and I exercise 4-5 times a week. I don’t have a thyroid because of cancer nine years ago."

• XXO...
• Taken for less than 1 month
• June 11, 2023

For Weight Loss (Obesity/Overweight) "I experienced vomiting within one hour, swelling of the throat, and difficulty swallowing, which has not stopped since the first and last dose on Sept 6th, 2023. Now hypersensitive to all regular daily medications and taking Benadryl several times per day."

• Jan...
• Taken for less than 1 month
• January 9, 2023

For Weight Loss (Obesity/Overweight) "Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

• Jan...
• Taken for less than 1 month
• January 9, 2023

For Weight Loss (Obesity/Overweight) "Took my first 0.25 mg Wegovy dose yesterday. I felt nauseous about an hour later, but within 2 hours, I started vomiting. For the next 16 hours, I dry heaved throughout the day and night. I couldn't even keep water down. It hasn’t been a full 24 hours yet since I took the shot and feel horrible, hoping that these side effects will stop soon. There is no way I’m taking another shot next week."

• Ran...
• Taken for less than 1 month
• September 21, 2020

For Type 2 Diabetes "I've been taking Ozempic for two weeks now. I wondered how this drug could allow some - or most - people to lose weight. Now I know - it makes you feel sort of sick to your stomach and takes away your appetite - at least that is my result so far. I am hoping to develop a tolerance to it. Not a really pleasant experience so far, but I have not vomited or had diarrhea as some users have reported. It does appear to be lowering my blood glucose somewhat, which is the primary reason I am taking it. I am also taking metformin but have been able to reduce the dosage. I am still only taking 0.25 mg of Ozempic, so the result of higher dosages is unknown now. I will post again in a month or two with higher dosage usage results."

• SSH...
• Taken for 1 to 6 months
• February 25, 2020

For Type 2 Diabetes "I have been on Rybelsus for 2 months. I started on the 3 mg and did fine, no side effects, and actually felt more awake and focused. Then I went to the 7 mg and was very nauseous and vomited almost nightly. It felt like my food never digested. I apparently am pretty sensitive to this medication and since my blood glucose and A1C have been good, I am taking this every other day, which has lessened the nausea and discomfort. I have lost 6 lbs in the past month and that has been great because I needed that. So we will see how this continues, but I feel pretty good."

• Deb...
• Taken for 1 to 6 months
• April 25, 2023

For Weight Loss (Obesity/Overweight) "I started using Ozempic in Feb 2023. During the first three weeks, I experienced a lot of vomiting and diarrhea, so I stopped using it. I waited for three weeks and then tried again. However, after two injections, I became severely dehydrated and ended up in the ICU at the Heart Center. I had collapsed at a baby shower due to dehydration and was experiencing blood loss in my stools, anemia, and electrolyte imbalances. I could have died, but thankfully, I am still here to share my story. Ozempic may work for some, but it is definitely not for me."

• Anonymous
• Taken for 1 to 6 months
• May 24, 2023

For Weight Loss (Obesity/Overweight) "Easy to administer, but during the first few weeks, had zero weight loss. Dose was increased. Woke in the middle of the night after the last dose with severe heartburn. Vomited every four hours for two days. Missed a day of work. Not able to keep anything down, including water. Put on anti-nausea medication. Have to sleep in a sitting position and take antacids and prescription meds to control heartburn enough to sleep. Cannot wait for the medication to get out of my system so I can function without vomiting or constant heartburn."

• MIC...
• Taken for 1 to 6 months
• November 5, 2020

For Type 2 Diabetes "A1C was 6.2 with Metformin. Went on Ozempic for 3 months. I had side effects of bad nausea, vomiting, and watery diarrhea. Lost 27 lbs. Couldn't eat 4/7 days. My A1C now 5.6, and it is not worth it for me."

• Har...
• September 16, 2022

For Weight Loss (Obesity/Overweight) "Avoid this injection. I took my first dose a few weeks ago, and I have never been so sick. Constant vomiting after 4 hours, throwing up bile. Ended up in the hospital as I became dehydrated. A week later, still got on and off vomiting. The reflux is terrible and can't eat anything. It's better to be yourself than go through all this."

• MDl...
• Taken for less than 1 month
• March 16, 2023

For Type 2 Diabetes "Do not use this drug. I took my first and only dose and had terrible diarrhea, so bad I had to cancel several engagements. I also had vomiting after eating, no appetite, a decline in vision, and worst was a mental haziness that took over a month to recover from. My doctor called it an allergic reaction, but I don’t believe that. Even after 8 months, I still have episodes of feeling tired and hazy. I feel like I’ve aged 5 years since taking the one dose. Other than type 2 diabetes, I was in good physical condition and health. Now I have aching muscles, reduced vision, and sporadic haziness. Yes, my A1C went down temporarily, but not worth all the rest of the side effects."

• Chi...
• Taken for 1 to 6 months
• May 3, 2021

For Type 2 Diabetes "Diabetic & prescribed Ozempic .25 once weekly for a month & .50 once weekly for the 2nd month. Then increased to 1. 1xwkly thereafter. By the time I hit the first week on .50, I was having daily nausea. I called the provider & was told to start the .50 to see if my body could adjust. By the 2nd dose, I had severe daily nausea culminating in volatile vomiting to the point I was severely limited in maintaining daily activities. I made the decision to stop the medication & notified the doctor that my body could not handle it. By this time, I was experiencing constant belly pain. It hurt to drink water & eat as I would throw it up. This was the worst experience & I was agitated that it will take 5 long weeks to clear my system. I'm thinking it should have stopped sooner."

• Che...
• Taken for 1 to 2 years
• September 7, 2024

For Weight Loss (Obesity/Overweight) "I sat out on a journey to lose weight in January 2023. I am a heart patient, and I was weighing 220 lbs for the first time in my life. I started in the beginning, I had lots of nausea and vomiting as I went through the different doses. It wasn’t until I got to the highest dose that I really saw the change in my body weight. The weight just slid off. I lost a total of 100 lbs. I definitely changed my diet: high protein, grilled veggies, and fruit. I will say it changed my taste buds. Salty things were overwhelming to me while on Wegovy, and so was sugar. I can’t eat cheese at all without getting sick. But I feel better. My heart is doing well, and my lipids are finally in the normal range. This medication helped save my life, and I feel so blessed. Good luck on your new journey, and don’t be afraid to ask your doctor for nausea meds, it helps a lot."

• ano...
• Taken for less than 1 month
• April 27, 2023

For Type 2 Diabetes "Horrible experience. After the first injection, woke up in the middle of the night with horrible heartburn. Then started projectile vomiting, uncontrollably for the next two days. I was so weak and dehydrated that I had to get fluids by IV. On the fourth day, I still cannot eat and was still sick to my stomach. These are evil meds and will never inject myself with this stuff again. Just awful."

• ATQ...
• Taken for less than 1 month
• March 13, 2023

For Type 2 Diabetes "I took my fourth dose of 3 mg Rybelsus this morning. I've followed all the directions, but it has been awful. I've been incredibly sick since the second day. I've been vomiting, nauseous, I've had a nonstop migraine, and every time I cough, vomit, sneeze, or gag, my entire upper body feels like it's being electrocuted. I emailed my doctor last night. Hopefully, I'll hear from her today. This is miserable."

• Bec...
• December 28, 2020

For Type 2 Diabetes "I started taking the Ozempic injection a week before Christmas and took my second 0.25 dose on Xmas Eve. I've felt slight nausea since taking it and very little desire to eat. My BS levels have been 95% in range ever since and have managed to reduce my long-acting insulin by 20 units. I have lost 6 lbs so far. I was astounded it came off in the first week. The only time I have had bad stomach pains is when I've eaten something bad, and I get terrible runs 20 mins after eating, but once I've been to the loo, pain stops. I had vomiting once because I think I overate a few days after taking it. I was super bloated, and a few hours later I threw up, then I felt fine again. So I just eat little and often, mostly grazing and picking at fruit. I was worried about taking this because of the comments I've read, and with having IBS, I didn't know if it would be bad for me. But I have no issues taking it, and so far, so good. It's still early days for me, but I would 100% recommend it."

• Dro...
• Taken for 6 months to 1 year
• April 2, 2025

For Type 2 Diabetes "I've lost about 40 lbs since starting Ozempic 11 months ago. My A1C is now within normal limits, but I still take Metformin. My non-alcohol fatty liver disease has resolved as well. I experienced nausea and vomiting early on in treatment, but that has mostly resolved. I feel hunger less and feel full longer. Constipation is a big problem, so I use an occasional stool softener or eat some prunes to keep things moving. The medication decreases the pleasure I get from food, which is weird sometimes. When I go out of town, I used to look forward to trying a new restaurant, but now it's just 'meh' no matter what I eat. I found that I have more nausea if I inject in the abdomen, so I do it in my arm or thigh instead."

• Ano...
• Taken for 6 months to 1 year
• April 20, 2025

For Weight Loss (Obesity/Overweight) "I started Wegovy in October at the lowest possible dosage and worked up to 1.7 by February. I had no side effects and very slowly lost weight, which I was fine with. I lost 35 pounds in six months. However, oddly enough, after five weeks at 1.7 with no side effects, I became quite ill. I started having the sulfur belches, followed by vomiting and severe diarrhea. I went to urgent care. They said it was a normal response and to take anti-diarrhea meds. I did. It got worse, to the point of diarrhea every 15-20 minutes. After six days of this, I went to the emergency room. They admitted me. I spent nine days in the hospital with severe dehydration, which caused my kidneys and pancreas to start shutting down. Docs felt I had a separate bacterial bug not caused by my shots. I was finally able to go home. My doctor had me start back at a safer .25 dose. I did, but immediately got sick again. I think I need to stop these meds, sadly, as they did originally help me, but I can’t go on this way."

• Tuu...
• Taken for 6 months to 1 year
• July 23, 2021

For Type 2 Diabetes "I started with 0.25 Ozempic in November 2020 and upped my dosage to 0.5 in January 2021. My A1C is the same as when I was taking 2000 mg Metformin daily (5.1-5.3%). My doctor decided to switch me to help with weight loss and manage my pre-diabetes. I have lost 47 lbs, which is great, but it isn't a healthy way to lose weight. I met with a GI specialist and was diagnosed with gastroparesis, they had me discontinue Ozempic to see if my symptoms would disappear. That was 6 weeks ago, and my stomach is still paralyzed. I have sulfur burps, diarrhea, severe constipation, and vomiting daily. I now have to eat a low FODMAP diet and can only manage a few mouthfuls of food at a time. I have no quality of life anymore, I can no longer enjoy many of the things I used to, which has caused me severe anxiety and depression. While the weight loss benefits sound appealing, please think twice before taking this drug."

• oag...
• Taken for less than 1 month
• June 13, 2023

For Type 2 Diabetes "This is terrible. It is my second time trying to take this medication. I have experienced vomiting, stomach ache, sweating, and chills. I feel so bad that I am not going to try 'to get used to this medication.'"

• Bad...
• Taken for less than 1 month
• July 9, 2022

For Cardiovascular Risk Reduction "I am on day 4 after taking this and now bedridden. I have never been so sick in my life: nausea, vomiting, gas, headache, terrible smelly burping, dizzy, blurred vision, the list goes on. I hope this wears off soon, I have to go back to work. I am so disappointed in this product, very scary how it's destroying my body. I can't eat, sleep, barely move, just sipping water. Terrible stuff."

• lad...
• Taken for less than 1 month
• April 17, 2023

For Type 2 Diabetes "Was taking Trulicity until 2 weeks ago. My VA hospital said they need to switch me to Ozempic. I agreed. Took my first dose 2 days ago after I was out of Trulicity, and I don't remember a time in my life I felt so sick. Acid reflux, abdominal cramps, sweating with chills, vomiting even if I sip water. I'm thin enough for the weight loss to be irrelevant, but being dehydrated is terrible. I won't be taking more of this."

• jas...
• Taken for 1 to 6 months
• December 31, 2022

For Cardiovascular Risk Reduction "Warning, this stuff will make you sick. I have been taking this for 2 months. In the first month, I had terrible diarrhea. It got so bad I ended up going to the hospital. I told my doctor, and he said he doubted it was Ozempic, so I tried it again in the 2nd month on a higher dose, and the 2nd week in, again I was terribly ill, vomiting for 4 days straight with intermittent diarrhea and feeling absolutely awful. My night sleep is very broken with stomach pains, increased wind, nausea. I'm now stopping using it."

• Fan...
• Taken for 1 to 6 months
• October 5, 2020

For Type 2 Diabetes "I have been on Rybelsus for 1.5 months. Can’t eat, and what I do eat makes me so nauseous that it all comes back up. I have lost 10 lbs, which is great, but if this upset stomach and throwing up do not go away, then it is not worth it. I’ll give it another week, but I think I will tell the doctor I am done. My sugar levels were high, and that is why he prescribed it to take along with Synjardy. Feeling sick all the time is not worth it."