Semaglutide and Tiredness: What Users Say (Page 5)

• dgb...
• Taken for 1 to 6 months
• June 24, 2023

Semaglutide for Type 2 Diabetes "Sick in the stomach, pain in the stomach, and dizziness! Worse as the dosage goes up. I am at 1 mg and have been sick all week! Extremely tired and want to sleep all the time! Have lost weight 15 lbs. always good. No appetite; nothing sounds good! I eat to relieve the pain in my stomach! Does not last! Easy to use! Such a tiny needle!"

• Ext...
• Taken for 1 to 6 months
• January 18, 2023

For Weight Loss (Obesity/Overweight) "I took my first injection on Dec 17, 2022, so I'm 4 1/2 weeks in (1 month). I'm on the 2.4 mg injection. Started at 30 units. Lost 9 lbs the first week. Gained weight the following weekend over Christmas, and also a bit over New Year's weekend. As of this morning, I'm down from 238.6 lbs to 218.4 lbs...that's 20 pounds in a month, including the weight I had to lose twice from gaining over the holiday weekends! I take my injections on Saturday. Side effects: nausea on Sunday, very, very light. Enough to notice, but not uncomfortable. Tired on Monday mornings. Take B12 and fine in a couple of hours. A little bit more tired on Tuesday mornings. Again, B12 and fine. Feel good on Wednesdays. Thursday, I have an abundance of energy. Friday afternoons, I can feel the rumblings of hunger, but don't really feel like eating. Saturday, it's time for the injection again, so the rumbling stops. I haven't experienced any other side effects."

• Jji...
• April 2, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "Awful. I felt tired and like I had morning sickness the whole time. Was on one month of .25 mg and two months on .5 mg. It never got better. I was constipated and on the verge of throwing up constantly. Also started post-menopausal bleeding despite being on HRT. All of this, and I only lost a whopping 9 pounds despite barely being able to eat even cereal. Your diet turns to garbage because you just stick to stuff that won’t make you feel more nauseous. You will not learn how to eat properly; just how not to eat foods that make you throw up. I just switched to phentermine, and I’ve already lost two pounds in 5 days. My energy is back. Zero side effects and less than $15/month. Read the long-term reviews, people. Unless you are going to stay on this for life, which I would never do seeing how it messed with my hormones, you will 100% gain it all back and then some."

• Zow...
• Taken for less than 1 month
• June 19, 2022

Semaglutide for Cardiovascular Risk Reduction "I've taken this to help with decreasing my appetite and got a higher BMI, I'm just under 15 stone. On 1 mg and talk about feeling tired, feeling a bit sick too. I not long woke up with bad reflux and nearly being sick that I couldn't breathe properly! (Basically nearly choked in my sleep!) I don't eat rubbish or drink fizzy pop, so I know it's not that. My throat hurts with the reflux. I really hope it doesn't stay for days or be sick often."

• Daw...
• Taken for less than 1 month
• May 24, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "Just started this new medication, and I’m on my second injection of the .25 mg. The side effects I have had are slight abdominal pain, acid reflux, nausea, and tiredness. I am 5’8 and was 244.5 lbs. To date, I am now 239 lbs - I’ve lost 6 lbs since 5-21-23. I weigh in every Sunday to stay on track of my weight and what it is. The side effects are mild, and I am going to stick with it because, like so many others, I’m tired of being TIRED… the weight has to go, and I encourage you to try this."

• Cad...
• Taken for 1 to 6 months
• April 7, 2025

Semaglutide for Weight Loss (Obesity/Overweight) "Mixed review: I took Wegovy for 5 months, hoping to ultimately lose 15-20 pounds. I didn’t start losing weight until I started the 1.7 mg dosage (third month), and at that dosage, I was exceedingly tired and achy. I lost 10 pounds in 4 months but stopped taking it because of these side effects. Four months later, without Wegovy, I’m still down 5 pounds. My insurance partially covered this with a significant copay because I also have cardiovascular risks. I’d recommend only if you don’t experience the same side effects."

• Nap...
• Taken for less than 1 month
• November 30, 2024

For Weight Loss (Obesity/Overweight) "No side effects until the end of week 2, spontaneous vomiting after lunch today. Nausea & immediately vomited until stomach empty. Feeling more tired than usual. Felt really cold last evening—used heating pad for warmth."

• Ted...
• Taken for 1 to 6 months
• February 12, 2025

For Weight Loss (Obesity/Overweight) "This drug has definitely helped with decreasing my appetite and decreasing sugar cravings. I've been on semaglutide for 6 weeks and have lost 13 lbs so far. As far as side effects go, I've experienced some tiredness, nausea, and some stomach discomfort. Nothing debilitating. I'm going through a weight loss center. I go once a week for counseling and injections. I started out at 0.25 injection the first 30 days and am now up to 0.5 injections once a week."

• Win...
• Taken for less than 1 month
• March 19, 2025

Semaglutide for Type 2 Diabetes "Ozempic has made me not want to eat much at all. When I first started, I had stomach cramps, gastro, but that is slowly passing. I often feel tired and have to take an afternoon nap as I can’t keep my eyes open."

• Ano...
• Taken for 1 to 6 months
• May 17, 2023

For Weight Loss (Obesity/Overweight) "It helped reach a reasonable goal of 20-25 pounds in about 5 months. The drawback for me was it made me tired and a little nauseous the few days after the weekly shot. It does suppress your appetite. Alcohol and bad foods will make you feel worse. And you will lose more weight from that. I would do this again. Hopefully won’t need much for maintenance."

• Sha...
• Taken for 1 to 6 months
• October 28, 2024

Semaglutide for Type 2 Diabetes "Type II diabetic with kidney disease. Been on Ozempic 18 weeks, and at 2.0 for 4 weeks. I felt great at 1.0, but not at 2.0. Lethargy and headaches non-stop now. Will see Dr. to go back to 1.0 after blood work. Good news: A1C went from 7.3 to 6.5. Glucose now close to normal range. Previously was between 260-335. Kidney function increased from 30-37. Lost 44 lbs. I am 62 and on disability."

• Liz...
• May 15, 2023

Semaglutide for Type 2 Diabetes "I am on the 3rd week of the 1 mg dose. I started with .25 for 4 weeks, then to .50 mg. My A1C is down from 9.9 to 7.8. I am 70 years old with HBP. My appetite has decreased. I started having constipation with 1 mg. I continue to have queasiness and tiredness since taking it. I lost 10 lbs since starting mid-January to mid-May."

• Dur...
• Taken for 1 to 6 months
• March 24, 2025

For Weight Loss (Obesity/Overweight) "Seven weeks using a weekly shot. That part is so easy. It killed off my appetite, but I'm only losing 1 lb a week; I expected it to work faster. I was on 0.25 for a month, then 0.5 this month. I tend to have heartburn, and it has been much worse, but is starting to calm down. The meds also gave me constipation and a lot of gas. The constipation is getting better. I've been tired. But I'm still taking it. I have lost my craving for sugar and have found that I'm attracted to healthy foods, although I don't eat much. I plan to continue on the semaglutide for some months more. Diets never worked for me. This works, just slowly."

• lol...
• Taken for 1 to 6 months
• September 26, 2024

For Weight Loss (Obesity/Overweight) "So far, I've been on it for one month. I lost 7 lbs, my goal is 10, so I've decided to stay on it one more month. I do get nauseated and exhausted quicker than usual, but if I sit for a minute, it usually passes. It definitely helped my calorie deficit. I had to tell myself to eat because I wasn't hungry most of the day, but very thirsty, so I drank about 1/2 to one gallon of water a day. It has diminished my cravings for sweets as well, I don't even want it. Good luck to everyone, I'm sure, as with anything, results are different for everyone. Be safe and eat fresh."

• Mav...
• Taken for 1 to 6 months
• April 16, 2023

Semaglutide for Type 2 Diabetes "I started Ozempic 5 weeks ago for type 2 diabetes, high cholesterol and triglycerides, and high blood pressure. I am obese at 5'2" and 222 lbs. I had no bad effects with feeling nauseous, etc., from day one, starting at a dose of 0.25 for the first month. However, I have had seasonal affective disorder for most of my life and feel slight depression during the winter months. I did not feel bad before starting, but from the first week, I was very tired and depressed. I was in slow motion, and for the last 5 weeks, I've felt more and more depressed. My stomach felt so heavy, and I could barely eat 900 calories a day. I realized that was not good for me and tried to eat more, but sometimes the only way to up the calories was to eat junk. I was worried after 5 weeks, so I have just stopped the meds. After 5 weeks, I lost 7 lbs. My cholesterol went from 260 to 237, my A1C went from 6.2 to 6.4 (I'd been working on that before). I will now try more lifestyle changes, and I'm starting to feel my old self again."

• Tom...
• Taken for 1 to 6 months
• May 1, 2023

For Type 2 Diabetes "During the 4th week of taking .25 mg of Ozempic, I developed severe vomiting for three days. I have an ostomy and experienced very high output while vomiting. The vomiting and high-output ostomy have stopped, but I continue to be very tired and sleep a lot. I lost about 15 lbs during this period. I assume most of this was water weight. My last dose was 11 days ago, but my appetite continues to be minimal. I recently had a HA1C, and it was down to 5.9 from 6.4 six months ago. I have also taken Metformin during this time."

• jos...
• Taken for less than 1 month
• September 2, 2024

Semaglutide for Type 2 Diabetes "Scared of taking any medications. Thus far, it has been dropping my numbers, however, I have been waking up and having difficulty falling back asleep. I am a bit tired during the day. Thus far, it looks like it is working."

• cor...
• Taken for 6 months to 1 year
• November 7, 2024

Semaglutide for Type 2 Diabetes "It’s working, my overall caloric intake has substantially decreased. Some weight loss, but disappointed with the amount. I expected 25 lbs of weight, and I only got 15 or so. My A1C is in a good place at 6.3. I feel lethargic and have dry mouth often."

• Aus...
• Taken for less than 1 month
• March 1, 2025

Semaglutide for Type 2 Diabetes "Male, 45, 101 kg (225 lb). Three weeks in. Still on 0.25 mg. Definitely less appetite and fine on a wrap for lunch and a light dinner. Have lost 4 kg (9 lbs). Occasionally feel a bit queasy, but never nauseous. Also feeling quite tired, but that could be the lower calories or lower blood sugar. Positive results from this initial phase. It definitely does what it says on the box."

• BHW...
• Taken for less than 1 month
• September 23, 2024

For Weight Loss (Obesity/Overweight) "I began taking the 0.25 dose 4 weeks ago (I will take my first dose of 0.5 this upcoming week). I was VERY hesitant to begin this journey due to the reviews I have read regarding side effects, but I am fortunate enough to not have experienced many. I can say I was a bit lethargic the first few days, and I do experience mild nausea if I do not eat. Prior to taking this drug, I was constantly hungry, and the food noise I experienced was constant - it regularly affected my daily functioning. However, about 48 hours after taking the first dose, I began to notice a difference. I legitimately have not experienced the sensation of hunger in 4 weeks, which is a GAME changer for me. I have not made any drastic changes to my diet or exercise, as I was already eating quite healthy and working out 3-6 days a week. I have lost 16 lbs - will update on my journey in a month or two."

• Ree...
• Taken for 1 to 6 months
• March 27, 2025

Semaglutide for Type 2 Diabetes "I’m 55. I was on Metformin 500 mg twice a day for 1 year. I was diagnosed with type 2 diabetes. This medication was making me sick, my sugar was not stable even though I was very careful about what I ate. I was feeling tired, body aches. I explained to my endocrinologist, she suggested I should stop right away. I was on Junivia 100 mg once a day, very same family as Ozempic. It cost the same, I lost 10 lbs. Then I switched to Ozempic injection 0.25 for a month, after 0.50. I didn’t feel any side effects, my body aches and tiredness were gone. But when I started 1 mg Ozempic injection once a week, it changed everything. I started to feel very tired, acid reflux, I felt extremely tired, no energy, dizziness. But now I’m thinking of talking to my endocrinologist and stopping after 3 months of use. My diabetic level is always stable at 6.2, 5.4, but I don’t like to feel very tired all the time. I hope my experience will help someone. But Metformin is not suitable for me."

• Sue...
• Taken for less than 1 month
• June 1, 2023

Semaglutide for Weight Loss (Obesity/Overweight) "I need help to decide if Ozempic is good for me. The side effects scare me: nausea, vomiting, constipation, and exhaustion. Yikes! I really need the weight loss, though. I really want to try it. I'm curious if insurance will cover it."

• Jnf...
• Taken for 6 months to 1 year
• October 11, 2020

Semaglutide for Type 2 Diabetes "I’ve been on Ozempic for almost a year and now started having extremely itchy skin, extreme gas, and just a feeling of lethargy. Has anyone else had the rash/itching?"

• Sid...
• Taken for 1 to 6 months
• September 5, 2024

Semaglutide for Cardiovascular Risk Reduction "I've only been taking this for a month. I am extremely tired the day after taking the shot for a full 24 hours. Not taking it anymore, but I did lose 7 pounds."

• Anonymous
• Taken for 1 to 6 months
• March 19, 2022

Semaglutide for Weight Loss (Obesity/Overweight) "Started 5 weeks ago, down 13 pounds. I have had little side effects with the exception of being tired more often. Just started 0.5 today."