Ozempic and Vomiting: What Users Say (Page 2)

• Kas...
• Taken for 1 to 6 months
• September 29, 2021

For Cardiovascular Risk Reduction "I have been on Ozempic for 3 months now, the first day I vomited but haven’t since, nausea for the first month or so, and I got very constipated, but now all is good and I suffer no side effects anymore. So far, I have lost 22 kg, I have no sugar cravings, and my appetite is right down, making sure I eat healthy meals is the only challenge as I do not feel like eating. But I could not recommend this enough to anyone who really struggles with food and weight loss."

• Dck...
• January 13, 2021

For Type 2 Diabetes "I’ve been on Ozempic for 8 weeks, .25 starter dose for the first 4 weeks; it suppressed my appetite, a couple of mild headaches, and intermittent nausea. Moved to .5 at week 5 and have no desire to eat at all. It’s almost a problem as I feel so weak and have all-day nausea. Hard to tell if the nausea is from not eating, Ozempic, or both. At week 6, I also started taking Humira for spondyloarthritis; the combined side effects are brutal. Sick nearly 24 hours a day, constant nausea, vomiting with any exertion. Backed off the Ozempic to .25; the side effects are better, but still troubling. As a positive, I’ve lost 30 lbs in 8 weeks, all from not eating as I feel too sick and weak to walk or work out. The docs prescribed Zofran 8 mg po every 8 hours as needed. It helps, and I do manage to eat a couple of small meals. Weigh the benefits and downsides, but it does work. A1C dropped from 8.7 to 7.4 in the first 8 weeks and should continue downward with prolonged use and accompanied weight loss."

• 9ru...
• Taken for 1 to 6 months
• September 10, 2022

For Cardiovascular Risk Reduction "Absolutely horrific. I get it works for most people, but unfortunately not me (and should not be promoted as a miracle drug that can help all obese people lose weight, as it doesn't work for everyone). I took 0.25 (the smallest dose) for 3 weeks and nothing (I yo-yoed with my weight; lost a bit then gained it again). After 3 weeks (not sure why 3 weeks for me), the main side effects kicked in. Diarrhea/loose stools, constipation, vomiting, nausea. Worst side effect was for 3 nights in a row, at about 3 a.m. I projectile vomited. First night I almost aspirated and choked on my own vomit trying to make it to the toilet without throwing up. Second night, even though I had the bathroom bin next to my bed, I was still projectile vomiting, and I couldn't sleep as I had a panic attack that I'd pass away overnight and my family would find me dead as I couldn't breathe as I had undigested food stuck in my esophagus. Gave up after 5 weeks of the lowest dose."

• Bis...
• April 7, 2023

For Weight Loss (Obesity/Overweight) "I am going on week 11 with Ozempic, and have lost 24 pounds. I have had all 5 of the main side effects, nausea, stomach pain, vomiting, diarrhea, and constipation. I am happy with the weight loss, so am learning to manage these. By trial and error, I've found that I can't eat much at one time (don't really want to), need to avoid fatty foods, drink lots of fluids, and take Senna laxative every night for the constipation, and keep Zofran around to help with nausea. Yes, these first few weeks have been difficult, but the weight loss is worth it to me. Plus, the side effects get less the longer I'm on Ozempic. I am currently on 1.0 mg and think that's quite enough. I am rarely hungry and often have to make myself eat. I hope to lose 65 pounds total."

• Thi...
• June 27, 2018

For Type 2 Diabetes "I've been taking this for 2.5 months. I've lost a solid 10 pounds. I take it right before bed so I can sleep off the initial side effects, if any. There is a little bit of diarrhea, nothing too crazy. I have major loss of appetite, I can eat half meals or half kids' meals and I'm always full after a few bites. Sugars are low. The major side effect is nausea, but it isn't every day. I've thrown up 3 times within the past 3 months, which is something I never did prior. It comes out of nowhere, and honestly, I'm unsure if it is this injectable or just from taking an iron supplement and vitamin. Could be the vitamin. I feel tired also, not sure if it's just work or a side effect. Overall, I'm happy with the injectable, plus it beats taking a pill every day."

• nau...
• December 30, 2020

For Type 2 Diabetes "I started Ozempic .25 mg subcut 8 days ago. I took my second dose yesterday. My first week, I ended up in the ED. I thought I had a bowel blockage or ileus. The ED visit was preceded by 6 hours of constant, sickening, odiferous belching, constant flatus, eruptive vomiting, cramping, and pain. A CT scan revealed gastric paresis. The event was precipitated by a fatty meal. I have since learned that the decreased gastric motility demands drastic changes in the volume of food intake, fat content, and most importantly, patience with what I consider to be major side effects. Now, I have no appetite. I am nauseated all the time, taking Zofran 4 mg before any meal. The belching is greatly reduced, same with flatus. I feel constipated, but that is easing off. I am avoiding high-fat foods and eating smaller portions. I am profoundly fatigued. Tomorrow, I am getting on the treadmill for 30 minutes each day to stimulate endorphin release to feel better. I have read the symptoms are reduced after 4-6 weeks."

• Anonymous
• Taken for less than 1 month
• March 25, 2022

For Type 2 Diabetes "After 2 injections of .25, I started having watery diarrhea. On day 3, I woke up and the diarrhea had leaked out and was in my underwear. I started violently vomiting that same evening. This was day 4 of diarrhea, now with vomiting. My blood sugar levels kept crashing. I rushed to the ER, I had an X-ray, every lab work/panel you can think of, and a CT scan - nothing. Ozempic is the only culprit. I am texting this review from my hospital bed. I was admitted and put on fluids and a liquid diet. They are trying to keep the nausea under control and stop these symptoms before it affects my kidneys from being dehydrated. The Ozempic has been thrown in the garbage, but I don't know how long the nightmare from that so-called medicine will last."

• jma...
• Taken for 1 to 6 months
• January 27, 2023

For Cardiovascular Risk Reduction "I started on the lowest dose of Ozempic in October 2022. One injection, in my thigh, once a week. I didn't make it past the first 4 weeks or the lowest dose. My physician hoped that since I do not have a gallbladder, many of the reported side effects of nausea and vomiting would not affect me. Wrong. First week and all things went well. I experienced no real side effects and had decreased appetite and energy. I slept well and was active. Second, third and fourth weeks, not so good. Modified my entire diet, but could barely eat or drink anything but a little chicken. Constant and severe nausea, vomiting, sleep deprivation, headaches, body aches, and zero energy for the next three weeks. It was like having a severe case of stomach flu for 4 weeks. Oh, I lost weight, between 18-20 lbs. Unfortunately, this is not a sustainable way of life. I couldn't function; I didn't leave my house for a month. I pulled myself off of it, and it took another 3 months to recover fully."

• Dro...
• Taken for 6 months to 1 year
• April 2, 2025

For Type 2 Diabetes "I've lost about 40 lbs since starting Ozempic 11 months ago. My A1C is now within normal limits, but I still take Metformin. My non-alcohol fatty liver disease has resolved as well. I experienced nausea and vomiting early on in treatment, but that has mostly resolved. I feel hunger less and feel full longer. Constipation is a big problem, so I use an occasional stool softener or eat some prunes to keep things moving. The medication decreases the pleasure I get from food, which is weird sometimes. When I go out of town, I used to look forward to trying a new restaurant, but now it's just 'meh' no matter what I eat. I found that I have more nausea if I inject in the abdomen, so I do it in my arm or thigh instead."

• Dia...
• Taken for 6 months to 1 year
• June 2, 2019

For Type 2 Diabetes "I’ve been on Ozempic about 8 months. I went to the 1 mg dose pretty quickly. My sugars became normal. I was losing about 5 lbs every two weeks. My A1C went from 6.8 to 5.6. No side effects at all. I’ve lost about 30 pounds overall. About 6 weeks ago, I got sulfur burps, then nausea, then vomiting. I vomited 9 times over maybe 6 hrs. Thought it was food poisoning. Yesterday, I again got sulfur burps followed by nausea and then vomiting. This morning again, burps, vomiting, and watery diarrhea. Thought it odd it would again be food poisoning. I never get sick. Then thought maybe it was E. coli or gastroparesis. Then I happened upon this site and started reading the reviews of Ozempic. I don’t know why it would take so many months for any side effects to show, but it sounds like this is most likely the cause of my vomiting and diarrhea. I took my last dose two days ago. I take it every two weeks. I think I’ll cut back to 0.50 next time and see what happens."

• No ...
• March 1, 2020

For Type 2 Diabetes "Victoza was no longer working to lower my A1C, so my doctor prescribed Ozempic. It’s been 4 weeks. Since I’d been on the maximum dosage of Victoza, she assumed it would be a smooth transition to the maximum dose of Ozempic. While it did reduce my blood sugar, I’ve had every side effect: nausea, vomiting, explosive diarrhea, heart palpitations, heartburn, and disgusting burping. Some days, I can’t leave the house. I didn’t immediately realize that these symptoms were related to the medication, so I continued to inject the maximum dosage. I thought I had a horrible bug. After the second week, I made the connection. So I went down to a half dose, but that wasn’t enough. Now I’m down to .25. I’m still having side effects, so for now, I am on 2 Prilosec, 2 Zofran, and 4 Imodium per day. My blood sugars are down, sometimes dangerously low. I lost weight, but of course, I would with the nausea, vomiting, and diarrhea. I’m going to try to stick it out."

• she...
• Taken for 1 to 6 months
• May 21, 2019

For Type 2 Diabetes "I started at a dose of 0.25 mg Ozempic, advancing to 1 mg weekly. The first week, I experienced reduced appetite and some nausea. Within 3 months, I have lost 35 pounds, and my HgA1C went from 9 down to 6. I have, on several occasions, experienced nausea and vomiting if I overate or had very greasy food. It does reduce your appetite substantially. I found eating my main meal at lunch and soup for supper has reduced nausea."

• Anonymous
• Taken for less than 1 month
• June 11, 2022

For Cardiovascular Risk Reduction "I started Ozempic for weight loss. I took dose 1 of 0.25 week 1 and had a little nausea. I took dose 2 on Saturday morning when I was supposed to. On Sunday, I felt terrible with nausea. Sunday night, I was vomiting and had diarrhea with major stomach pains. These symptoms have now lasted 6 days. My body is in so much pain and discomfort from vomiting and diarrhea and unable to eat or drink. I would never recommend this drug to anyone. The side effects are so terrible that I would not want to take the chance. I’m hoping these symptoms will go away soon."

• JRo...
• Taken for 1 to 6 months
• October 29, 2019

For Type 2 Diabetes "Within 2 weeks after moving from the starter dose of Ozempic to 0.25 to 0.5, I began having vomiting in the wee hours of the morning, with increasing intensity, nearly every night for the last 2+ weeks. The last 4-5 have been really rough. I also take metformin 500 and glimepiride 2, both AM and PM. This weekend, I went down to the Ozempic 0.25 dose, but Sunday and Monday nights were both awful bouts of vomiting. (No diarrhea at any stage with Ozempic; occasional nausea during the day, very decreased appetite.) Is anyone else having this bad and persistent vomiting? Thanks and good luck."

• Jan...
• Taken for 1 to 6 months
• October 11, 2021

For Cardiovascular Risk Reduction "This was prescribed by a weight loss nurse, second time use. First time on .25 mg was okay, but as soon as I go up to .5 mg I am so sick. Diarrhea, nausea, vomiting, sulfur burps, it's horrendous!! I do not having tried twice now, with the same effects each time I can say 100% do not try this for weight loss. It is not worth it. It takes 5 weeks to clear the body too!"

• Pea...
• October 25, 2018

For Type 2 Diabetes "I started taking Ozempic 3 months ago. I found that after I take my injection on Wednesday night, I get nausea before the day is over and vomit. It feels like my food gets stuck and won’t move. I get sick at least once a week, then I’m better. My appetite has decreased. I also notice I can’t overeat, or I get sick. I have told my doctor, he thinks it will get better. I know one thing for sure: you can’t cheat with fried food, or you will be sick for sure. I’m going to try one more month."

• ERM...
• Taken for less than 1 month
• February 25, 2019

For Type 2 Diabetes "This drug should be taken off the market. Side effects are severe. Belching, uncontrollable diarrhea, dehydration, nausea, vomiting. Be prepared to not leave your bathroom for 3 days every week. Not to mention, the ads are by far the most annoying on TV."

• AK4...
• Taken for 1 to 6 months
• April 11, 2023

For Weight Loss (Obesity/Overweight) "I started Ozempic for weight loss. I paid cash since I wasn't approved by insurance. I was about 15-20 pounds overweight and pre-diabetic with a family history of type 2 diabetes. No matter what I did, nothing made me lose weight. The first month at .25 mg was a dream come true. I had no appetite and felt very few side effects. I lost 10-12 pounds in the first month. The 5th shot was .5 mg. I became so ill. It started with huge belches and nausea. That night I vomited and was so lethargic and nauseous that I didn't get out of bed for 3 days. I had weird sores on my tongue. The next day I vomited again. I had to get Zofran for the nausea, which helped a bit. Almost a week later, I am due for this week's shot, and I have decided not to continue. I still have the belches from hell, weakness, and lethargy, but I am at least able to function and work. Climbing the stairs feels like Mt. Everest. I hope I feel normal again soon."

• PDH...
• Taken for 1 to 6 months
• June 21, 2019

For Type 2 Diabetes "I started Ozempic about 3 months ago at .25 mg. My doctor made me start my 1st dose on a Monday in her office because I would tell her I would try and then never do it. Tuesday morning I was good, then by Tuesday night, stomach cramps, nausea, vomiting, and diarrhea, till the wee hours of the morning. The symptoms slowed down throughout the week. Even though I was losing at least 3-4 pounds a week, a total of 35 pounds within a 2 1/2 month period. My A1C did go down, the side effects are deadly. I like the fact that I am losing weight, but I hope I don't have permanent damage from this medication."

• Bai...
• Taken for less than 1 month
• July 3, 2019

For Type 2 Diabetes "At first, I had a brief overwhelming bout of nausea that passed. Decreased appetite definitely had me losing weight, but after the second injection, the nausea got much worse! Plus, I had diarrhea/vomiting, and it just got worse daily. I had to discontinue. Now it's been a month later, and I'm still having nausea and diarrhea. Horrible experience for me."

• Nes...
• Taken for 1 to 6 months
• May 3, 2019

For Type 2 Diabetes "Was diagnosed with type 2 diabetes in March 2019. Doctor put me on Ozempic rather than insulin, although it's not recommended. He thought it was worth a try along with 500 mg metformin twice daily. The first 3 weeks of 0.25 mg Ozempic were just fine. Very minimal side effects - occasional diarrhea, some gas, and belching. Nothing I couldn't handle. The fourth week of 0.25 mg was worse. Constant diarrhea for four days, nausea, some vomiting. I went to a different doctor thinking I had a stomach virus, he prescribed me an anti-diarrheal, and I felt better. I took the Ozempic at 0.5 mg then, as prescribed. Two days later, nightmare. Diarrhea again, vomiting, nausea, and serious fatigue. I'm in the throes of it right now, and I'm going to be contacting my doctor to see what I can do to counteract this. Besides the side effects, though, it's working beautifully. My blood sugar is down from the high 300s to the low 100s in just a month."

• Ley...
• Taken for 1 to 6 months
• June 3, 2023

For Weight Loss (Obesity/Overweight) "From the initial starting dose until I went up to 1 mg, the whole 6 months was a roller coaster of nausea, headaches, and uncontrollable vomiting. The nausea was always followed by throwing up 5-7 times per day. If I ate or drank anything with too much sugar (including fresh orange juice), then I would throw it up within 30 mins. The sulfate mouth smell, along with the vomiting, was difficult and embarrassing. Exhausted and tired feeling, along with feeling depressed and hating/disgusted by food, is how I felt. I did lose about 8 kgs before moving on to Saxenda. Get ready for Ozempic to destroy your life for a few months if you want to lose weight with it."

• Tes...
• Taken for 1 to 6 months
• May 14, 2023

For Type 2 Diabetes "So I began Ozempic just a few months ago. Just took my first 1 mg dose last week, and I have to say, I am sick all the time. Anything I eat is for sure going to end up in the toilet one way or another. The diarrhea is out of control and constant. When I was only on the 0.25 mg dose, I had a window of the day where I was actually able to eat and not vomit it up later, but since going all the way up to the 1 unit, I cannot keep anything down. I have two small children, and I feel exhausted all the time from the vomiting and the nausea. I have decided today that I will discontinue this medicine as I cannot deal with the severe side effects. Even Zofran isn’t working."

• Ann...
• Taken for 6 months to 1 year
• February 11, 2025

For Type 2 Diabetes "I was on Ozempic for about a year, lost +/- 14 kgs. Diabetes was controlled. After about 9 months of taking it, I started suffering with upper and lower tummy cramps and once had nausea and vomiting. Went in for an ultrasound, it showed I had a fibroid on my left ovary and my GP said I had colitis. Treated me with Nexium and Buscopan and asked me to stop the Ozempic as that was causing the colitis. Tummy cramps have not gone away completely as it's been a month since I stopped Ozempic, but I started feeling hungry all the time and it's so bad that if I don't eat, I start shaking and feel very weak. Oh, and I also started feeling very weak in my legs, not numb but tingly sort of. Sometimes I feel as if I'm going to fall to the floor in a puddle. Not sure if that is also related to the Ozempic."

• Dee...
• Taken for 1 to 6 months
• June 2, 2019

For Type 2 Diabetes "I am so grateful for this site. I thought I was alone in experiencing these awful side effects. Yesterday was the worst. Started with horrible rotten egg burping. Woke up with vomiting. I started on 0.5 and decreased to 0.25 because I was experiencing nausea all the time. I am tired. Two weeks ago, I had severe constipation. It really helps with glucose control. I have been on it for four weeks. I plan to see my MD this week. I don't think I can continue. I've only lost 1 lb so far."