Ozempic and Vomiting: What Users Say (Page 2)

• Pho...
• Taken for less than 1 month
• December 21, 2018

For Type 2 Diabetes "Was prescribed and took only one dose. Within 12 hours, I was vomiting and had severe nausea. My reaction landed me in the hospital for 8 days. If you have, or even suspect you have, gastroparesis, DO NOT take this drug. I was nearly put on a feeding tube because of Ozempic. It was not a reaction to but an actual severe side effect of this drug. It also affected my vision. Now who is going to pay the ER and hospital bill I have to deal with?"

• Dro...
• Taken for 6 months to 1 year
• April 2, 2025

For Type 2 Diabetes "I've lost about 40 lbs since starting Ozempic 11 months ago. My A1C is now within normal limits, but I still take Metformin. My non-alcohol fatty liver disease has resolved as well. I experienced nausea and vomiting early on in treatment, but that has mostly resolved. I feel hunger less and feel full longer. Constipation is a big problem, so I use an occasional stool softener or eat some prunes to keep things moving. The medication decreases the pleasure I get from food, which is weird sometimes. When I go out of town, I used to look forward to trying a new restaurant, but now it's just 'meh' no matter what I eat. I found that I have more nausea if I inject in the abdomen, so I do it in my arm or thigh instead."

• Sug...
• Taken for less than 1 month
• September 20, 2019

For Type 2 Diabetes "Took my first dose of .25 on 9/11 with no side effects at all. When I took the second dose was when everything went bad. After about 1 hour after the 2nd dose, I noticed my stomach started tightening up, so I didn't think much of it until I started driving and vomiting all over the place. Was vomiting for about 12 hours, then started getting bad stomach cramps. Today is 9/19, and I decided that I'm not taking this no more and wouldn't recommend this to anyone, not even my worst enemy. THIS STUFF IS NOT GOOD AT ALL!!"

• Dia...
• Taken for 6 months to 1 year
• August 16, 2019

For Type 2 Diabetes "58 yo. Woman. Type 2 for 30 yrs. Morbidly obese most of adult life. At 50 years old, had RNY gastric bypass surgery, went from 315 lbs with A1c of 13.5 with meds to 115 lbs. It worked too well. Even so, diabetes wasn’t even close to being cured. A1c was 8.5 at best with Invokana & Metformin. I used every drug there is with little improvement. So, a year ago, started Ozempic .5. Nausea & vomiting for 2 weeks, but then it subsided. After 2 more weeks, went to 1 mg. I don’t get nauseous anymore, but my appetite is completely gone, which is good if you’re overweight, but I’m a bag of bones, so I have to graze on tiny amounts of food all day & night. Because of the weight loss surgery, I already got dumping & can’t eat fatty food or sugar, so it’s difficult, but it’s better than dying from diabetes. It all depends on the person, so try it & see if the side effects go away like they did with me. I’m going to get labs, and if they’re still good, I’m staying with it."

• Shy...
• Taken for 1 to 6 months
• March 26, 2022

For Cardiovascular Risk Reduction "I always had some side effects of Ozempic. Mainly exhaustion, nauseous, occasional throwing up after eating, constipation. As month 3 came and the dose increased to 1 mg, I ended up in the emergency room. I was vomiting and had liquid diarrhea for 4 days. My heart rate was elevated, and my potassium was dangerously low. At the time, I thought it was a stomach bug-until the next injection caused the same effects. I've been on anti-nausea medication since. I can see why it takes the appetite away-being exhausted and nauseous 24/7 is terrible. Potassium is still not where it should be. Hoping this gets out of my system fast."

• Nev...
• Taken for 1 to 6 months
• July 10, 2019

For Type 2 Diabetes "I've had a similar experience while on Ozempic. I lost 20 lbs in 2 months, but the vomiting and bloating got worse. I went to the ER on the 1st of July and just got home today. I was diagnosed with acute pancreatitis due to Ozempic. I think these companies need to do more studies before prescribing this to us. We aren't lab rats."

• Wen...
• Taken for 1 to 6 months
• November 30, 2018

For Type 2 Diabetes "Hospitalized twice with severe abdominal pain and nausea, diarrhea, and vomiting. Second visit had a gastric emptying study done. Normal gastric emptying is 30 min, mine was 800 min. Basically, this med damaged the vagus nerve and paralyzed my stomach, not allowing food to empty. Severe symptoms. Missed work, hospitalized a total of over 2 weeks. Praying my stomach returns to normal. Diagnosed with gastroparesis caused by Ozempic."

• Clo...
• September 2, 2019

For Type 2 Diabetes "Tried Ozempic for the first time on Thursday. Friday night, a bit of diarrhea, Saturday, just felt off, Sunday went out for breakfast, discovered I had little appetite. And then it was non-stop vomiting and diarrhea, to the point I was in the ER. Spent several hours there as they tried to bring the lactic acid back down into a normal range. They told me the higher the lactic acid, the more severe the dehydration. Multiple IVs, anti-nausea shots, and something to stop the diarrhea, plus one CT scan, they said stomach bug. I could go home and recover in bed. Stupid me believed them. Took the injection for the second time on Thursday...same thing, only this time the abdominal cramping was so bad it doubled me over, to the point I was sent by ambulance to the ER. Same round of tests, same results. Only this time, add in pain meds. After comparing the previous Sunday to the current Sunday, they pretty much concluded no stomach bug the first time, but it was due to the injection."

• Ann...
• Taken for 1 to 6 months
• November 11, 2019

For Type 2 Diabetes "Doctor suggested switching to Ozempic after weight loss plateaued with Victoza. Ozempic caused an instant headache lasting several days and nausea. Very noticeable as I never have headaches. The real problem was that two days after taking the shot, I would throw up and be too nauseous to get out of bed for about 12 hours. For the first two weeks, I thought it was food poisoning, but the vomiting was nothing like that. It was a slow, inexorable process, not like my body had to get rid of something bad that I ate. Had also not been sick enough to vomit in years, then it happened three out of four weeks in a row. Switched back to Victoza, no more headache and vomiting. Ozempic was more convenient as it is a weekly shot, but I'd rather not be sick one day a week. The vomiting was awful."

• Suz...
• Taken for 1 to 6 months
• May 3, 2019

For Type 2 Diabetes "I started on Ozempic in January this year. I have been type 2 diabetic for over 15 years. I was on metformin but found my A1C increasing, so it was recommended that I try this. I have had no problems with nausea, vomiting, diarrhea, or stomach pains, etc. that others have had. I have lost 26 lbs and am using 1 ml per week. I started with the .25, after two weeks increased to .5, and then after 4 weeks increased to 1 ml. My daily blood test has decreased down from around 10-11 to 4.5-6, and my A1C reduced down from 11 to 8, that was 2 months ago. I will redo next month. I truly think it will be down under 7 when I do it. For me, it is the miracle drug, I feel so much better, and with the weight loss, I feel less tired. I am sure it does not work for everyone, but for those it does, it is a very good product. I did have to get approval through my endocrinologist for my drug plan to cover this. Those without a drug plan would be well advised to think carefully as it is very expensive."

• DAn...
• May 12, 2021

For Cardiovascular Risk Reduction "Within 12 hours of the first dose, vomiting occurred and continued for 3 days. Unable to keep any food down; small sips of ginger ale the only thing I did not vomit. Lower abdominal tight cramping. Pain in the upper abdomen. Vomiting at all times of day and night, which added to the fatigued feeling. Days 4-7 felt queasy. Second injection: same side effects as first. Emetrol helped me eat dry toast (1/2 slice) and weak tea. Third dose: same effects, but only for 2-1/2 days."

• Sic...
• September 7, 2019

For Type 2 Diabetes "Started Ozempic .25 dose 2 weeks ago. First week, ended up in the ER with dehydration from vomiting so much. Physicians didn't think it was this medication that was causing it. Endocrinologist was not available as it was Labor Day when this occurred. I didn't think anything of it, so I continued with another dose two days ago. This was a very stupid idea. I am severely nauseous with no vomiting this time, but it is miserable. Also a lot of sulfur burps. This lasted half the day today and is subsiding. But this is like a roller coaster and unsure when these symptoms will return. I am also experiencing fatigue nonstop. Hard to even move or concentrate energy. I thought this might be due to having normal blood sugar levels since taking this medication, but I don't think this is the case. Please be careful on this medication."

• Jus...
• Taken for less than 1 month
• May 13, 2023

For Weight Loss (Obesity/Overweight) "I started Ozempic .5 mg once a week. I have taken it for 3 weeks. I have had to stop it because I have been so sick. I have had massively bad headaches, nausea, vomiting, and stomach pain. After the first injection, I ended up in the ER because of my stomach pain, and then again 5 days later. I haven't been able to keep anything down. I can barely keep 2 sips of water down. I can't even take any of my prescription medications because I am constantly throwing them back up. My doctor told me to stop taking it. My husband says I've lost weight, but that's only because I'm constantly throwing everything up."

• Cau...
• March 3, 2022

For Type 2 Diabetes "I took .25 for about 6 months and thought this was a miracle drug. Caused slight constipation, but I dealt with it. When they increased me to .5 mg, I started violently vomiting the next day. No one could figure out what was wrong with me. Pancreatic enzymes were high, but not high enough to diagnose pancreatitis. I could barely eat for two months. Gas, bloating, side pain, back pain, stomatitis pain, non-stop burping, constipation, nausea, vomiting off and on. My food perpetually felt like it was backed up into my mouth. They had to take me off of the drug, and now my sugars are higher than ever, and no one can help me. They were okay before, but now doctors consider me as failing two types of drug classes because of this, won't give me my old meds back, and I may have to go on insulin. I am gaining weight like never before and am so tired that I can barely function. They now believe it gave me gastroparesis, and I can't get better. I would recommend this medicine to no one."

• Dis...
• August 30, 2018

For Type 2 Diabetes "I started Ozempic and had no issue with the initial dose of .25. When I had the second dose, I had minor nausea and definitely noticed not feeling as hungry. Five days later, I had severe diarrhea and very foul-tasting burping. The next day, I was okay. Then the following day, I had diarrhea again. I thought maybe stomach virus. Imodium helped me get through the rest of the day. Then it was the day I take my shot (Sunday night). Monday was okay, and then it started again with the terrible-tasting burps, severe diarrhea, nausea, and vomiting. I was unable to eat anything except ice chips. The diarrhea has continued for now the third day. I literally can’t be more than 10 steps from the bathroom. I’ve only had water, chicken broth, 1 banana, 1/2 cup applesauce, 1/2 cup plain rice, and 1 cup apple juice and still can’t stay away from the bathroom. I’ve lost 7 pounds since starting Ozempic, 4 of them have been this week. This is not how I want to lose weight."

• Ter...
• Taken for 1 to 6 months
• April 1, 2021

For Cardiovascular Risk Reduction "After 6 weeks, I cried 'uncle!' (admit defeat). Severe and profuse diarrhea, ++ nausea, and bouts of ++ vomiting, and stomach pain all the time caused me to give up on this drug. Lost only 5 pounds in 5 weeks, and I'm sure it was from the extreme GI issues and inability to eat more than 500-600 calories on bad days - mostly just soup! Felt like I had food poisoning for 6 weeks straight. Was hopeful for this drug, but it totally didn't work for me, and the side effects were unbearable - and I'm a tough cookie."

• Hat...
• Taken for less than 1 month
• July 19, 2022

For Cardiovascular Risk Reduction "This is the worst medication I have ever had. Side effects of egg burps, vomiting, bloating so bad. DO NOT TAKE THIS. 30% of people that try this drug end up having problems with it. DO NOT TAKE. You can't eat, everything that goes into you makes you want to throw up. DON'T TAKE! Never-ending nausea and weakness. DON'T USE, SAVE YOURSELF. Headaches....."

• Kas...
• Taken for 1 to 6 months
• September 29, 2021

For Cardiovascular Risk Reduction "I have been on Ozempic for 3 months now, the first day I vomited but haven’t since, nausea for the first month or so, and I got very constipated, but now all is good and I suffer no side effects anymore. So far, I have lost 22 kg, I have no sugar cravings, and my appetite is right down, making sure I eat healthy meals is the only challenge as I do not feel like eating. But I could not recommend this enough to anyone who really struggles with food and weight loss."

• Dck...
• January 13, 2021

For Type 2 Diabetes "I’ve been on Ozempic for 8 weeks, .25 starter dose for the first 4 weeks; it suppressed my appetite, a couple of mild headaches, and intermittent nausea. Moved to .5 at week 5 and have no desire to eat at all. It’s almost a problem as I feel so weak and have all-day nausea. Hard to tell if the nausea is from not eating, Ozempic, or both. At week 6, I also started taking Humira for spondyloarthritis; the combined side effects are brutal. Sick nearly 24 hours a day, constant nausea, vomiting with any exertion. Backed off the Ozempic to .25; the side effects are better, but still troubling. As a positive, I’ve lost 30 lbs in 8 weeks, all from not eating as I feel too sick and weak to walk or work out. The docs prescribed Zofran 8 mg po every 8 hours as needed. It helps, and I do manage to eat a couple of small meals. Weigh the benefits and downsides, but it does work. A1C dropped from 8.7 to 7.4 in the first 8 weeks and should continue downward with prolonged use and accompanied weight loss."

• Gre...
• Taken for less than 1 month
• September 27, 2019

For Type 2 Diabetes "Took first Ozempic shot in doctor's office. Felt okay through the week. Took second shot and started getting sick that night. Diarrhea and vomiting. My wife had to help me off the floor of the bathroom. Missed 2 days of work. Had to make an emergency visit to the doctor to get pills to stop vomiting. And the sulfur burps were horrible."

• Bis...
• April 7, 2023

For Weight Loss (Obesity/Overweight) "I am going on week 11 with Ozempic, and have lost 24 pounds. I have had all 5 of the main side effects, nausea, stomach pain, vomiting, diarrhea, and constipation. I am happy with the weight loss, so am learning to manage these. By trial and error, I've found that I can't eat much at one time (don't really want to), need to avoid fatty foods, drink lots of fluids, and take Senna laxative every night for the constipation, and keep Zofran around to help with nausea. Yes, these first few weeks have been difficult, but the weight loss is worth it to me. Plus, the side effects get less the longer I'm on Ozempic. I am currently on 1.0 mg and think that's quite enough. I am rarely hungry and often have to make myself eat. I hope to lose 65 pounds total."

• 9ru...
• Taken for 1 to 6 months
• September 10, 2022

For Cardiovascular Risk Reduction "Absolutely horrific. I get it works for most people, but unfortunately not me (and should not be promoted as a miracle drug that can help all obese people lose weight, as it doesn't work for everyone). I took 0.25 (the smallest dose) for 3 weeks and nothing (I yo-yoed with my weight; lost a bit then gained it again). After 3 weeks (not sure why 3 weeks for me), the main side effects kicked in. Diarrhea/loose stools, constipation, vomiting, nausea. Worst side effect was for 3 nights in a row, at about 3 a.m. I projectile vomited. First night I almost aspirated and choked on my own vomit trying to make it to the toilet without throwing up. Second night, even though I had the bathroom bin next to my bed, I was still projectile vomiting, and I couldn't sleep as I had a panic attack that I'd pass away overnight and my family would find me dead as I couldn't breathe as I had undigested food stuck in my esophagus. Gave up after 5 weeks of the lowest dose."

• Lau...
• January 21, 2021

For Type 2 Diabetes "I started Ozempic mid-November, with my first injection at 25 mg. Within two days, I had the worst bloating, my stomach bulged. I felt horrible. I had nasty sulfur burps and gas. This lasted for 24 hours. I noticed a decrease in my sweet tooth, and I cut back on my food intake. I lost 10 lbs within the first 4 weeks of taking Ozempic. After 4 weeks, my doctor told me to increase my dosage to .50 mg. I delayed increasing it by 4 weeks. On Monday, I increased my dosage to .50 mg. Day 3, I got really sick, bloating, sulfur burps, and gas were horrible. I vomited at least 2 times. I was super hungry but couldn’t hold food down. All I wanted to do was sleep. By morning, I felt 80% better. Still burping and gassy, but not nauseous or vomiting anymore. I do not plan to continue to take the .50 mg. I will just stick with 25 mg. The misery I felt was excruciating, and I can’t handle it. My next appointment is next month, and I am curious to know if my A1C had decreased or not."

• nau...
• December 30, 2020

For Type 2 Diabetes "I started Ozempic .25 mg subcut 8 days ago. I took my second dose yesterday. My first week, I ended up in the ED. I thought I had a bowel blockage or ileus. The ED visit was preceded by 6 hours of constant, sickening, odiferous belching, constant flatus, eruptive vomiting, cramping, and pain. A CT scan revealed gastric paresis. The event was precipitated by a fatty meal. I have since learned that the decreased gastric motility demands drastic changes in the volume of food intake, fat content, and most importantly, patience with what I consider to be major side effects. Now, I have no appetite. I am nauseated all the time, taking Zofran 4 mg before any meal. The belching is greatly reduced, same with flatus. I feel constipated, but that is easing off. I am avoiding high-fat foods and eating smaller portions. I am profoundly fatigued. Tomorrow, I am getting on the treadmill for 30 minutes each day to stimulate endorphin release to feel better. I have read the symptoms are reduced after 4-6 weeks."

• Thi...
• June 27, 2018

For Type 2 Diabetes "I've been taking this for 2.5 months. I've lost a solid 10 pounds. I take it right before bed so I can sleep off the initial side effects, if any. There is a little bit of diarrhea, nothing too crazy. I have major loss of appetite, I can eat half meals or half kids' meals and I'm always full after a few bites. Sugars are low. The major side effect is nausea, but it isn't every day. I've thrown up 3 times within the past 3 months, which is something I never did prior. It comes out of nowhere, and honestly, I'm unsure if it is this injectable or just from taking an iron supplement and vitamin. Could be the vitamin. I feel tired also, not sure if it's just work or a side effect. Overall, I'm happy with the injectable, plus it beats taking a pill every day."